Advertisement

Medical Oncology

, Volume 15, Issue 4, pp 286–288 | Cite as

Non-secretory solitary plasmacytoma of the spleen

  • Milica D Čolović
  • GM Janković
  • RB Čolović
  • Vesna M Martinović-Čemerikić
Case Report

Abstract

A case of primary nonsecretory plasmacytoma of the spleen is reported. On laparotomy and splenectomy a 920 g spleen was removed, measuring 16×14×6 cm. The cut surface of the entire spleen showed that the tumour occupied most of the splenic tissue. A bone marrow aspirate and trephine, skeletal survey showed no signs of myeloma. Biopsy of the liver and regional lymph nodes was normal. Immunocytochemistry of the splenic tumour showed positivity for pan-B and plasma cell markers. After splenectomy the patient was treated with chemotherapy according to protocol VBCMP (M2).

Keywords

spleen plasmacytoma non-secretory splenectomy 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Woodruff RK, Whittle JM, Malaps JS. Solitary plasmacytoma; extramedullary soft tissue plasmacytoma.Cancer 1979;43: 2340–2343.PubMedCrossRefGoogle Scholar
  2. 2.
    Marsch WCH, Gross VM. Frequency and pathomorphology of extramedullary manifestations in plasma cell myeloma of the skeleton.Pathol Res Pract 1978;163: 115–127.PubMedGoogle Scholar
  3. 3.
    Bjørn-Hansen R. Primary plasmacytoma of the spleen.AJR 1973;117: 81–83.Google Scholar
  4. 4.
    Perry-Thornton E, Verly GP, Karkala J, Walker M. An unusual presentation of multiple myeloma: primary plasmacytoma of the spleen.J Natl Med Assoc 1989;81: 1095–1099.PubMedGoogle Scholar
  5. 5.
    Sonobe T, Yoshioko I, Okafuji T. A case of extramedullary plasmacytoma of the spleen.Rinsho Hoshasen 1989;34: 375–377.PubMedGoogle Scholar
  6. 6.
    Stringfellow HF, Solomon LR, Nicholson CM, Howat AJ. Acute renal failure by primary splenic plasmacytoma.Nephrol Dial Transplant 1995;10: 128–129.PubMedGoogle Scholar
  7. 7.
    Wiernik PH. Neoplastic Diseases of the Blood, 3rd edn. Churchill Livingstone, 1996, pp 586–587.Google Scholar

Copyright information

© Stockton Press 1998

Authors and Affiliations

  • Milica D Čolović
    • 1
  • GM Janković
    • 1
  • RB Čolović
    • 2
  • Vesna M Martinović-Čemerikić
    • 2
  1. 1.Institute of HematologyClinical Center of SerbiaBelgradeYugoslavia
  2. 2.Institute of Digestive DiseasesClinical Center of SerbiaBelgradeYugoslavia

Personalised recommendations