Abstract
Recently, recommended dietary allowances (RDA) have been formulated by the Dutch Nutrition Council for minerals and trace elements, including iron (Fe). For some population groups in the Netherlands, it is questionable whether they easily meet the Fe recommendation. An increase in Fe intake is not always possible, but “manipulation” of Fe bioavailability ultimately may result in better Fe utilization. Various factors are known to affect Fe bioavailability. Generally, much attention is paid to diet-related factors, such as inhibitors and enhancers of Fe availability for absorption. Factors such as pH, oxidation potential, structure of food, and time of digestion often are overlooked. Of the diet-related factors, heme Fe and ascorbic acid have a strong positive effect on Fe availability for absorption, whereas oxalate and polyphenols seem to be strong inhibitors of Fe availability. Because of the many interactions that may occur simultaneously, the net effect of the various combined factors in a meal is not equal to the sum of the individual factors.
This is a preview of subscription content, access via your institution.
Similar content being viewed by others
References
Nutrition Council,Voeding 47, 159 (1986).
Ministries of Welfare, Health and Cultural Affairs, and Agriculture and Fisheries, Wat eet Nederland (results nationwide survey 1987/1988), Rijswijk, The Netherlands (1988).
T. Hazell,Wld. Rev. Nutr. Diet. 46, 1 (1985).
Bioavailability '88, August 21–24, 1988, Norwich, UK.
W. van Dokkum, inNutrient Availability, D. Southgate, I. Johnson, and G. R. Fenwick, eds., Royal Society of Chemistry, Cambridge, UK, 1989, pp. 89–96.
J. D. Cook,Food Techn. 37, 124 (1983).
A. P. MacPhail, T. H. Bothwell, J. D. Torrance, D. P. Derman, W. R. Bezwoda, R. W. Charlton and F. Mayet. Br. J. Nutr. 45, 215 (1981)
A. Wise,Nutr. Abstr. Rev. 53, 791 (1983).
K. T. Smith,Food Techn. 37, 115 (1983).
J. D. Cook and E. R. Monsen,Am. J. Clin. Nutr. 29, 859 (1976).
L. Hallberg, L. Solvell, and H. Brice,Acta Med. Scand. 459, Suppl. 11 (1966).
D. R. van Campen,J. Nutr. 103, 139 (1973).
L. A. Berner and D. D. Miller,Food Chem. 18, 47 (1985).
H. M. Crews, J. A. Burrell, and D. J. McWeeny,Z. Lebensm. Unters. Forsch. 180, 221 (1985).
E. R. Monsen, L. Hallberg, M. Layrisse, D. M. Hegsted, J. D. Cook, W. Mertz, and C. A. Finch,Am. J. Clin. Nutr. 31, 134 (1978).
F. M. Clydesdale,Food Techn. 37, 133 (1983).
S. R. Lynch and J. D. Cook,Ann. N.Y. Ac. Sci. 355, 32 (1980).
L. Rossander, L. Hallberg, and E. Björn-Rasmussen,Am. J. Clin. Nutr. 32, 2484 (1979).
E. B. Finley and F. L. Cerklewski,Am. J. Clin. Nutr. 37, 553 (1983).
E. R. Morris and R. Ellis,J. Nutr. 106, 753 (1976).
J. G. Reinhold, F. Ismail-Beigi, and B. Faradji,Nutr. Rep. Int. 12, 75 (1975).
J. G. Reinhold, J. S. Garcia, and P. Garzon,Am. J. Clin. Nutr. 34, 1384 (1981).
W. van Dokkum,Front. Gastrointest. Res. 14, 135 (1985).
R. Ellis, E. R. Morris, and A. D. Hill,Nutr. Res. 2, 319 (1982).
O. L. Oke,Wld. Rev. Nutr. Diet. 10, 262 (1969).
P. B. Disler, S. R. Lynch, R. W. Charlton, J. D. Torrance, T. H. Bothwell, R. B. Walker, and F. Mayet,Gut 16, 193 (1975).
L. Hallberg and L. RossanderHum. Nutr.: Appl. Nutr. 36A, 116 (1982).
C. Stitt, P. J. Charley, E. M. Butt, and P. Saltman,Proc. Soc. Exp. Biol. Med. 110, 70 (1962).
G. W. Bates, J. Boyer, J. C. Hegenauer, and P. Saltman,Am. J. Clin. Nutr. 25, 983 (1972).
T. Hazell and I. T. Johnson,Br. J. Nutr. 57, 223 (1987).
E. K. Amine and D. M. Hegsted,J. Agric. Food Chem. 23, 204 (1975).
B. L. O'Dell, inTrace Elements in Nutrition of Children, R. K. Chandra, ed., Raven, New York, 1985, pp. 41–62.
K. G. Porter, D. McMaster, M. Elmes, and A. H. G. Love,Lancet 2, 774 (1977).
E. A. Yetley and W. H. Glinsmann,Food Techn. 37, 121 (1983).
L. K. Henriksen, J. R. Mahalko, and L. A. K. Johnson,J. Am. Diet. Ass. 85, 563 (1985).
C. Martinez-Torres, I. Leets, P. Taylor, J. Ramirez, M. del Valle Camacho, and M. Layrisse,J. Nutr. 116, 1720 (1986).
T. H. Bothwell, R. W. Charlton, J. D. Cook, and C. A. Finch,Iron Metabolism in Man, Blackwell Scientific Publications, Oxford, UK, 1979.
K. R. Mahaffey,Federation Proc. 42, 1730 (1983).
P. R. Flanagan, J. S. McLellan, J. Haist, M. G. Cherian, M. J. Chamberlain, and L. S. Valberg,Gastroenterology 74, 841 (1978).
L. Hallberg, inVitamin C, J. N. Counsell and D. H. Hornig, eds., Applied Science Publishers, London, 1981, pp. 49–61.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
van Dokkum, W. Significance of iron bioavailability for iron recommendations. Biol Trace Elem Res 35, 1–11 (1992). https://doi.org/10.1007/BF02786233
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02786233