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Influence of microbial phytase and dietary calcium on the accumulation of lead in different organs of pigs

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Abstract

The objective of this study was to investigate the influence of microbial phytase and calcium supplementation to diets for growing pigs on the retention of lead in the kidney, liver, muscle, brain, and bone (phalanx 1). The experiments were carried out with barrows over the body weight range from 17 to 50 kg. The average lead concentration of the diets was 1.45 mg/kg dry matter. Diets were prepared with or without a supplement of 800 units of microbial phytase. The calcium concentration in the diets was 6.53 or 13.4 g/kg dry matter. The addition of microbial phytase showed an increase of lead concentration in bone. By increasing the calcium concentration to 13.4 g/kg dry matter, it was possible to avoid the phytase-induced increase of lead retention in bone.

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References

  1. J. Pallauf, G. Rimbach, et al., Dietary effect of phytogenic phytase and an addition of microbial phytase to a diet based on field beans, wheat, peas and barley on the uti- lization of phosphorus, calcium, magnesium, zinc and protein in piglets, Z.ErnÄhrungsw. 33, 128–135 (1994).

    Article  CAS  Google Scholar 

  2. J. Pallauf, G. Rimbach, et al., Effect of phytase supplementation to a phytate-rich diet based on wheat, barley and soya on the bioavailability of dietary phosphorus, cal- cium, magnesium, zinc and protein in piglets,Agribiol. Res. 47, 39–48 (1994).

    CAS  Google Scholar 

  3. A. Pointillart, Enhancement of phosphorus utilization in growing pigs fed phytate- rich diets by using rye bran,J. Anim. Sci. 69, 1109–1115 (1991).

    PubMed  CAS  Google Scholar 

  4. L. Young, M. Leunissen, and J. Atkinson, Addition of microbial phytase to diets of young pigs,J. Anim. Sci. 71, 2147–2150 (1993).

    PubMed  CAS  Google Scholar 

  5. X. G. Lei, P. K. Ku, et al., Supplemental microbial phytase improves bioavailability of dietary zinc to weanling pigs,J. Nutr. 123, 1117–1123 (1993).

    PubMed  CAS  Google Scholar 

  6. D. Farrell, E. Martin, et al., The beneficial effects of a microbial feed phytase in diets of broiler chickens and ducklings,J. Anim. Physiol. Anim. Nutr. 69, 278–283 (1993).

    CAS  Google Scholar 

  7. H. Edwards, Dietary 1,25 Dihydroxycholecalciferol supplementation increases nat- ural phytate phosphorus utilization in chickens,J. Nutr. 123, 567–577 (1993).

    PubMed  CAS  Google Scholar 

  8. P. C. Simons, H. A. J. Versteegh, et al., Improvement of phosphorus availability by microbial phytase in broilers and pigs,Br. J. Nutr. 64, 525–540 (1990).

    Article  PubMed  CAS  Google Scholar 

  9. S. Sebastian, S. P. Touchburn, et al., The effects of supplemental microbial phytase on the performance and utilization of dietary calcium, phosphorus, copper, and zinc in broiler-chickens fed corn-soybean diets,Poult. Sci. 75, 729–736 (1996).

    PubMed  CAS  Google Scholar 

  10. H. J. Lantzsch, Studies on nutritional effects of phytate in monogastric animals (rat, pig),übers. TierernÄhrung 18, 197–211 (1990).

    CAS  Google Scholar 

  11. G. Rimbach and J. Pallauf, Effect of an addition of microbial phytase on zinc- availability, Z.ErnÄhrungsw. 31, 269–277 (1992).

    Article  CAS  Google Scholar 

  12. M. Düngelhoef and M. Rodehutscord, Wirkung von Phytasen auf die Verdaulichkeit des Phosphors beim Schwein,übers. TierernÄhrung 23, 133–157 (1995).

    Google Scholar 

  13. A. Wise and D. J. Gilburt, Binding of cadmium and lead to the calcium-phytate com- plex in vitro,Toxicol. Lett. 9, 45–50 (1981).

    Article  PubMed  CAS  Google Scholar 

  14. E. Schulz and H. J. Oslage, Untersuchungen zur intestinalen Hydrolyse von Inosit- phosphorsÄureester und zur Absorption von Phytinphosphor beim Schwein. 2. Mit- teilung: Untersuchungen zur Hydrolyse der InositphosphorsÄureester im Verdauungstrakt des Schweines,J. Anim. Physiol. Anim. Nutr. 30, 76–91 (1972).

    CAS  Google Scholar 

  15. A. Sandberg, T. Larsen, and B. Sandstrom, High dietary calcium level decreases colonic phytate degradation in pigs fed a rapeseed diet,J. Nutr. 123, 559–566 (1993).

    PubMed  CAS  Google Scholar 

  16. H. J. Lantzsch, S. Wjst, and W. Drochner, The effect of dietary calcium on the efficacy of microbial phytase in rations for growing pigs,J. Anim. Physiol. Anim. Nutr. 73, 19–26 (1995).

    Article  CAS  Google Scholar 

  17. National Research Council,Nutrient Requirements of Domestic Animals, National Acad- emy Press, Washington, DC, pp. 1–93 (1988).

    Google Scholar 

  18. W. OelschlÄger, W. Huss, and L. Bestenlehner, Untersuchungen über Bleigehalte in Futtermitteln,Landw. Forschung 27, 272–280 (1974).

    Google Scholar 

  19. G. Crössmann, Schwermetalle in handeis- und wirtschaftseigenen Futtermitteln,Berich. Landwirtsch. 55, 785–795 (1977).

    Google Scholar 

  20. Bundesministerium für ErnÄhrung, Landwirtschaft und Forsten,Futtermittelverord- nung, (1992), Bundesgesetzblatt No.53, November21, 1992, p. 1898.

  21. F. Hsu, L. Krook, et al., Interactions of dietary calcium with toxic levels of lead and zinc in pigs,J. Nutr. 105, 112–118 (1975).

    CAS  Google Scholar 

  22. K. B. Nolan, P. A. Duffin, and D. J. McWeeny, Effects of phytate on mineral bioavail- ability. In vitro studies of Mg2+, Ca2+, Fe3+, Cu2+ and Zn2+ (also Cd2+) solubilities in the presence of phytate,J. Sci. Food Agric. 40, 79–85 (1987).

    Article  CAS  Google Scholar 

  23. W. J. Evans and C. J. Martin, Interactions of inositol hexaphosphate with Pb(II) and Be(II)—a calorimetric study. XVIII,J. Inorg. Biochem. 45, 105–113 (1992).

    Article  CAS  Google Scholar 

  24. J. I. Bullock, P. A. Duffin, et al., Effect of phytate on the in-vitro solubility of Al3+, Ca2+, Hg2+ and Pb2+ as a function of pH at 37 degrees C,J. Sci. Food Agric. 67, 507–509 (1995).

    Article  CAS  Google Scholar 

  25. C. Valiente, E. Molla, et al., Cadmium binding capacity of cocoa and isolated total dietary fibre under physiological pH conditions,J. Sci. Food Agric. 72, 476–482 (1996).

    Article  CAS  Google Scholar 

  26. A. Wise, Protective action of calcium phytate against acute lead toxicity in mice,Bull. Environ. Contamin. Toxicol. 27, 630–633 (1981).

    Article  CAS  Google Scholar 

  27. A. Wise, Blood lead levels after chronic feeding to mice of lead acetate with calcium phytate in the diet,Bull. Environ. Contamin. Toxicol. 29, 550–553 (1982).

    Article  CAS  Google Scholar 

  28. H. E. Rose and J. Quarterman, Effects of dietary phytic acid on lead and cadmium uptake and depletion in rats,Environ. Res. 35, 482–489 (1984).

    Article  PubMed  CAS  Google Scholar 

  29. H. E. Rose and J. Quarterman.Influence of Dietary Phytic Acid and Calcium on Lead Retention in the Rat, Proc. 5th Int. Symposium on Trace Elem. in Man and Anim., ed. Mills, C. F., Bremner I. and J. K. Chesters, p.170, (1984).

  30. H. Schenkel,Zur Rolle des Calciums als Inhibitor bei höheren Schadstoffbelastungen, Forschungsbericht No. 538031, Deutsche Landwirtschaftsgesellschaft Frankfurt, pp. 1–46 (1988).

  31. D. Oberleas, M. E. Muhrer, and B. L. O’Dell, Dietary metal-complexing agents and zinc availability in the rat,J. Nutr. 90, 56–62 (1966).

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Institute of Animal Nutrition (450), Hohenheim University, D-70593, Stuttgart, Germany

    B. Zacharias, H. J. Lantzsch & W. Drochner

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  1. B. Zacharias
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  2. H. J. Lantzsch
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  3. W. Drochner
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Zacharias, B., Lantzsch, H.J. & Drochner, W. Influence of microbial phytase and dietary calcium on the accumulation of lead in different organs of pigs. Biol Trace Elem Res 70, 243–249 (1999). https://doi.org/10.1007/BF02783833

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  • DOI: https://doi.org/10.1007/BF02783833

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