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Trace element correlations in the blood of indian women with breast cancer

Biological Trace Element Research volume 64, pages 237–245 (1998)Cite this article

Abstract

Fourteen minor (Na, K, P, Fe) and trace (Br, Co, Cr, Cs, Hg, Rb, Sb, Se, Sr, Zn) elements have been determined in pre and postoperative blood samples of 10 breast-cancer-affected. Indian women and compared with controls. The study showed elevation of Cr, Hg, Fe, Rb, Sb, and Zn and lowering of Se, K, P, and Sr contents in the blood of cancer patients. Most elemental contents in pre and postoperative stages remain unaltered except Br, Co, and Sb. Statistical significance of Fe, Se, Zn, and Hg levels has been tested by box plots. Lowering of Se in blood (-54.4%) is correlated with its enhancement in cancerous breast tissue (94.7%) of various clinical stages. Se/Zn and Se/Fe ratios are lowered in the blood of cancer patients, whereas Na/K ratio is only marginally enhanced. An attempt has been made to correlate Se levels with the dietary intake and breast cancer risk vis-a-vis American and Japanese women.

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  1. Department of Chemistry, Nagpur University, 440010, Nagpur, India

    Vivek Singh & A. N. Garg

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  1. Vivek Singh
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  2. A. N. Garg
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Singh, V., Garg, A.N. Trace element correlations in the blood of indian women with breast cancer. Biol Trace Elem Res 64, 237–245 (1998). https://doi.org/10.1007/BF02783340

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  • DOI: https://doi.org/10.1007/BF02783340

Index entries

  • Breast cancer
  • trace elements
  • blood
  • neutron activation analysis
  • selenium
  • zinc
  • dietary intake