Abstract
Meals of 12 diets were prepared from conventional foods with precautions against contamination by metallic elements because of epidemiologic associations between ischemic heart disease and the metabolism of magnesium, calcium, copper, and zinc. Magnesium, calcium, copper, and zinc were measured by atomic absorption spectrometry with satisfactory accuracy and precision.
The mean daily amount of copper in the diets was less than the apparent adult requirement. Mean amounts of magnesium and zinc were close to apparent requirements; however, adults consuming amounts less than one standard deviation below these means may be depleting body stores and be at risk of pathology.
Magnesium and copper were highly correlated (r=0.849,P=0.0001) in meals. This and other significant correlations probably will prevent the relationships of these elements to ischemic heart disease from being elucidated by epidemiology. Metabolic experiments will be necessary to differentiate among several hypotheses.
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Klevay, L.M. Magnesium, calcium, copper, and zinc in meals. Biol Trace Elem Res 4, 95–104 (1982). https://doi.org/10.1007/BF02783250
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DOI: https://doi.org/10.1007/BF02783250
Index Entries
- Calcium, and heart disease epidemiology
- copper, and heart disease epidemiology
- epidemiology, of Mg, Ca, Cu, and Zn in heart disease
- ischemic heart disease, and Mg, Ca, Cu, and Zn
- magnesium, and heart disease epidemiology
- trace elements, in heart disease epidemiology
- zinc, in heart disease epidemiology
- heart disease epidemiology, of Mg, Ca, Cu, and Zn