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Two cases of gastric antral vascular ectasia-Response to medical treatment

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Summary

Two patients with severe iron deficiency anemia and gastric antral vascular ectasia (GAVE) are reported. The anemia caused by the chronic blood loss from the abnormally dilated mucosal and submucosal capillary veins in the gastric antrum was unresponsive to oral iron supplementation. However, one of the patients was successfully treated with intramuscular injection of (Asu17) eel calcitonin. The other one was treated by oral prednisolone with resulting improvement iron deficiency anemia. The possible mechanisms of successful calcitonin and prednisolone treatments on chronic blood loss from GAVE is discussed.

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Authors and Affiliations

  1. Department of Internal Medicine, Miki City Hospital, 58-1 Kasa, Miki-shi, 673-04, Hyogo, Japan

    Kiyohiko Kishi, Yoshikazu Kinoshita M.D., Naoto Kitajima, Toshio Itoh, Chiharu Kawanami, Tetsuya Inadome, Tsutomu Inoh & Hisashi Fukuzaki

  2. Kobe University School of Allied Medical Sciences, Kobe, Japan

    Makoto Watanabe

  3. Third Department of Medicine, Kobe University School of Medicine, Kobe, Japan

    Masaaki Fukase & Takuo Fujita

  4. Department of Geriatrics, Kobe University School of Medicine, Kobe, Japan

    Tsutomu Chiba

Authors
  1. Kiyohiko Kishi
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  2. Yoshikazu Kinoshita M.D.
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  3. Naoto Kitajima
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  4. Toshio Itoh
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  5. Makoto Watanabe
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  6. Chiharu Kawanami
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  7. Tetsuya Inadome
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  8. Tsutomu Inoh
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  9. Hisashi Fukuzaki
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  10. Masaaki Fukase
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  11. Takuo Fujita
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  12. Tsutomu Chiba
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Kishi, K., Kinoshita, Y., Kitajima, N. et al. Two cases of gastric antral vascular ectasia-Response to medical treatment. Gastroenterol Jpn 26, 757–762 (1991). https://doi.org/10.1007/BF02782864

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  • DOI: https://doi.org/10.1007/BF02782864

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