Summary
A Brunner’s cyst, removed from a 54-year-old woman, was studied by light and electron microscopy. The cyst was spherical, measured 1.5 cm in diameter and was located in the duodenal bulb. Histologically, the cyst, confined in the submucosa, consisted of a single layer of epithelial cells and connective tissue. The epithelial cells were composed of an orderly array of tall columnar cells containing basal round nuclei and fine granular cytoplasm. Ultrastructurally, the epithelial cells contained many secretory granules in the cytoplasm. Each secretory granule was membrane-bound and appeared electron-lucid with a dense core. They were small and sparse around the Golgi apparatus but large and numerous in the apical region. Multinucleated cells were intermingled with cells of the epithelial lining.
Similar content being viewed by others
References
Leeson TS, Leeson CR: The fine structure of Brunner’s gland in man. J Anat 103: 263–276, 1968
Moe H: The ultrastructure of Brunner’s gafl the cat. J Ultrastruct Res 4: 58–72
Nakamura T, Yamashiro M, Suzuki Y: Benign tumor of the duodenum. Stomach and Intestine 4: 375–384, 1969
Osborne R, Toffler R, Lowman RM: Brunner’s gland adenoma of the duodenum. Am J Dig Dis 18: 689–693, 1973
Robertson HE: The pathology of Brunner’s glands. Arch Path 32: 112–130, 1941
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Taura, M., Taura, S., Kummerow, F.A. et al. An ultrastructural study of the Brunner’s cyst. Gastroenterol Jpn 12, 241–244 (1977). https://doi.org/10.1007/BF02781769
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02781769