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Aeroallergen contact dermatitis

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Conclusion

The recent advances in the field of aeroallergen contact dermatitis have provided new concepts that may help in managing patients with AD. First, progress should be made in improving our tools for patch testing with aeroallergens, and a consensus would be welcome for the standardization of allergens and testing methods. More epidemiological and follow-up studies are needed to assess the relevance of aeroallergen PT data. It seems reasonable to admit from the literature reviewed that a subset of patients with AD can improve with a manipulation of their environment, like a subset seen mostly in infants and young children improves after selective avoidance diets. However, in other patients, delayed responses to aeroallergens may have no relevance and could indicate merely the existence of other IgE-dependent mechanisms contributing to late-phase reactions in atopy. This phenomenon might be considered as a further marker of the atopic status, left sometimes undetected when only intradermal tests are used. The awareness of the development of IgE-dependent mechanisms via the epidermis may encourage the prevention of AD in predisposed individuals by reinforcing the epidermal barrier (63), especially in infancy, for example, by using large amounts of emollients, among other usual measures to decrease exposure to common aeroallergens. (64)

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Taïeb, A., Ducombs, G. Aeroallergen contact dermatitis. Clinic Rev Allerg and Immunol 14, 209–223 (1996). https://doi.org/10.1007/BF02780200

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