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Geographic heterogeneity of hepatocellular carcinoma

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References

  1. Sung J-L: Hepatitis B virus infection and its sequelae in Taiwan. Proc Natl Sci Counc B ROC 1981;5:385/399

    Google Scholar 

  2. Liver Cancer Study Group of Japan: Survey and follow-up study of primary liver cancer in Japan - Reprot 8. Acta Hepat Jap 1988;29:1619–1626

    Google Scholar 

  3. Berman C: Primary carcinoma of the liver. Lewis, London. 1951;19–98

    Google Scholar 

  4. Steiner PE: Cancer of the liver and cirrhosis in trans-Saharan Africa and the United States of America. Cancer 1960;13:1085–1166

    Article  Google Scholar 

  5. Kew MC: Clinical, pathologic, and etiologic heterogeneity in hepatoccllular carcinoma: evidence from South Africa. Hepatology 1981;1:366–369

    Article  PubMed  CAS  Google Scholar 

  6. Okuda K, Peters RL, Simson IW: Gross anatomical features of hepatocellular carcinoma from three disparate geographic areas. Proposal of new classification. Cancer 1984;54:2165–2173

    Article  PubMed  CAS  Google Scholar 

  7. Saracci R, Repetto F: Time trends of primary liver cancer; Indication of increased incidence in selected cancer registry populations, J Natl Cancer Inst 1980;65:241–247

    PubMed  CAS  Google Scholar 

  8. Okuda K, Fujimoto I, Hanai A, et al: Changing incidence of hepatocellular carcinoma in Japan. Cancer Res 1987;47:4967–4972

    PubMed  CAS  Google Scholar 

  9. Bartoloni S, Orner F, Giannini A, et al: Hepatocellular carcinoma and cirrhosis: a review of their relative incidence in a 25-year period in the Florence area. Hepato-Gastroenterology 1984;31:215–217

    Google Scholar 

  10. Iwama, Ohnishi K, Nakayama Y, et al: A clinical study of hepatocellular carcinoma (HCC) in relation to hepatitis B seromarkers. Implications of non-A, non-B hepatitis (NANB). Hepatology 1982;2:117 (Abst)

    Google Scholar 

  11. Munoz N, Bosch S: Epidemiology of hepatocellular carcinoma. In: Okuda K, Ishak KG, eds. Neoplasms of the liver. Springer-Verlag, Tokyo. 1987;3–19

    Google Scholar 

  12. Ihde DC, Sherlock P, Winawer SJ, et al: Clinical manifestations of hepatoma. Am J Med 1974;56:83–91

    Article  PubMed  CAS  Google Scholar 

  13. Dunham LJ, Bailar JC: World maps of cancer mortality rates and frequency rates. J Natl Cancer Inst 1968;41:155–203

    PubMed  CAS  Google Scholar 

  14. Waterhouse J, Muir C, Powell J: Cancer incidence in five continents. World Health Organization, Lyon 1977

    Google Scholar 

  15. Hidgginson JS: The epidemiology of primary carcinoma of the liver. In: Pack GT, Ishlami AH, eds. Tumors of the liver. Springer, Berlin. 1970;39–50

    Google Scholar 

  16. Kew MC, Marcus R, Gedes EW: Some characteristics of Mocambican Shangaans with primary hepatocellular cancer. S Afr Med J 1977;51:306–309

    PubMed  CAS  Google Scholar 

  17. Robertson MA, Harington JS, Bradshaw E: The cancer pattern in Africans at Barawanath Hospital, Johannesburg. Br J Cancer 1971;25:377–384

    PubMed  CAS  Google Scholar 

  18. Tiribelli C, Melato M, Croce LS, et al: Prevalence of hepatocellular carcinoma and relation to cirrhosis; comparison of two different cities of the world - Trieste, Italy and Chiba, Japan. Hepatology 1989;10:998–1002

    Article  PubMed  CAS  Google Scholar 

  19. Harington JS, McGlashan ND, Bradshaw E, et al: A spatial and temporal analysis of four cancers in African gold miners from southern Africa. Br J Cancer 1975;31:665–678

    PubMed  CAS  Google Scholar 

  20. Van Rensburg SJ, Cook-Mozaffari P, Van Schalkwyk DJ, et al: Hepatocellular carcinoma and dietary aflatoxin in Mozambique and Transkai. Br J Cancer 1985;51:3–26

    Google Scholar 

  21. Cova L, Wild CP, Mehrotra R, et al: Contribution of aflatoxin B1 and hepatitis B virus infection in the induction of liver tumors in ducks. Cancer Res 1990;50:2156–2163

    PubMed  CAS  Google Scholar 

  22. Beasley RP, Hwang LY, Lin CC, et al: Hepatocellular carcinoma and hepatitis B virus. A prospective study of 11,707 men in Taiwan. Lancet 1981;2:1129–1133

    Article  PubMed  CAS  Google Scholar 

  23. Sakuma K, Takahara T, Okuda K, et al: Prognosis of hepatitis B virus surface antigen carriers in relation to routine liver function tests: a prospective study. Gastroenterology 1982;83:114–117

    PubMed  CAS  Google Scholar 

  24. Colombo M, Kuo G, Choo QL, et al: Prevalence of antibodies to hepatitis C virus in Italian patients with hepatocellular carcinoma. Lancet 1989;2:1006–1008

    Article  PubMed  CAS  Google Scholar 

  25. Kiyosawa, K, Sodeyama T, Tanaka E, et al: Interrelationship between blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus. Hepatology (in press)

  26. Simson IW: Membranous obstruction of the inferior vena cava and hepatocellular carcinoma in South Africa. Gastroenterology 1982;82:171–178

    PubMed  CAS  Google Scholar 

  27. Nakamura T, Nakamura S, Aikawa T, et al: Obstruction of the inferior vena cava in the hepatic portion and the hepatic veins. Angiology 1968;19:479–498

    Article  PubMed  CAS  Google Scholar 

  28. Datta DV, Saha S, Singh SAK, et al: Chronic Budd-Chiari syndrome due to obstruction of the intrahepatic portion of the inferior vena cava. Gut 1972;13:372–378

    Article  PubMed  CAS  Google Scholar 

  29. Edmondson HA, Steiner PE: Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsies. Cancer 1954;7: 462–503

    Article  PubMed  CAS  Google Scholar 

  30. Okuda K, Musha H, Nakajima Y, et al: Clinicopathological features of encapsulated hepatocellular carcinoma. A study of 26 cases. Cancer 1977;40:1240–1245

    Article  PubMed  CAS  Google Scholar 

  31. Okuda K, Nakashima T, Kojiro M, et al: Hepatocellular carcinoma without cirrhosis in Japanese patients. Gastroenterology 1989;97:140–146

    PubMed  CAS  Google Scholar 

  32. Popper H: Viral versus chemical hepatocarcinogenesis. J Hepatol 1988;6:229–238

    Article  PubMed  CAS  Google Scholar 

  33. Skinhøj P, Hart Hansen JP, Nielsen NH, Mikkelsen F: Occurrence of cirrhosis and primary liver cancer in an Eskimo population hyperendemically infected with hepatitis B virus. Am J Epidemiol 1978;108:121–125

    PubMed  Google Scholar 

  34. Popper H. Thung SN, McMahon BJ, et al: Evolution of hepato-cellular carcinoma associated with chronic hepatitis B virus infection in Alaskan Eskimos. Arch Path Lab Med 1988;112:498–504

    PubMed  CAS  Google Scholar 

  35. Kew MC, Desmyter J, Bradburnc AF, et al: Hepatitis-B virus infection in Southern African blacks with hepatocellular cancer. J Natl Cancer Inst 1979;62:517–520

    PubMed  CAS  Google Scholar 

  36. Szmuness W: Hepatocellular carcinoma and the hepatitis B virus: evidence for a causal association. Prog Med Virol 1978;24: 40–69

    PubMed  CAS  Google Scholar 

  37. Okuda K: Early recognition of hepatocellular carcinoma. Hepatology 1986;6:729–738

    Article  PubMed  CAS  Google Scholar 

  38. Arakawa M, Kage M, Sugihara S, et al: Emergence of malignant lesions within an adenomatous hyperplastic nodule in a cirrhotic liver. Observations in five cases. Gastroenterology 1986;91:198–208

    PubMed  CAS  Google Scholar 

  39. Okuda K: What is the preneoplastic lesion for hepatocellular carcinoma? J Gastroenterol Hepatol 1986; 1:79–83

    Google Scholar 

  40. Kondo F, Wada K, Nagato Y, et al: Biopsy diagnosis of well-differentiated hepatocellular carcinoma based on new morphologic criteria. Hepatology 1989;9:751–755

    Article  PubMed  CAS  Google Scholar 

  41. Livraghi T, Sangalli G, Vettori C: Adenomatous hyperplastic nodules in the cirrhotic liver: a therapeutic approach. Work in progress. Radiology 1989;170:155–157

    PubMed  CAS  Google Scholar 

  42. Peter RL: Pathology of hepatocellular carcinoma. In: Okuda K, Peters RL, eds. Hepatocellular carcinoma. Wiley, New York. 1976;107–168

    Google Scholar 

  43. Roles DB: Fibrolamellar carcinoma of the liver. In: Okuda K, Ishak KG, eds. Neoplasms of the liver. Springer-Verlag, Tokyo. 1987;137–142

    Google Scholar 

  44. Paradinas FJ, Melia WM, Wilkinson ML, et al: High serum vitamin B12 binding capacity as a marker of the fibrolamellar variant of hepatocellular carcinoma. Br Med J 1982;285:840–842

    Article  CAS  Google Scholar 

  45. Nakashima T. Okuda K, Kojiro M, et al: Pathology of hepatocellular carcinoma in Japan: Two hundred thirty-two consecutive cases autopsied in 10 years. Cancer 1983;51:863–877

    Article  PubMed  CAS  Google Scholar 

  46. Buchanan TF, Huvos AG: Clear cell carcinoma of the liver. A clinicapathologic study of 13 patients. Am J Clin Pathol 1984;61:529–539

    Google Scholar 

  47. Lai CL, Wu PC, Lam KC, et al: Histologic prognostic indicators in hepatocellular carcinoma. Cancer 1979;44:1677–1683

    Article  PubMed  CAS  Google Scholar 

  48. Okuda K. Nakashima T: Primary carcinoma of the liver. In: Bockus: Gastroenterology 4th Ed. Saunders, Philadelphia. 1985:3315–3376

    Google Scholar 

  49. Okuda K, Suzuki N, Kubo Y, et al: Clinical aspects of hepatocellular carcinoma. In: Thatcher N, ed. Medical oncology, research and education. Vol. 9, Digestive cancer. Pergamon, Oxford. 1979;133–140

    Google Scholar 

  50. Kew MC: Alpha-fetoprotein in primary liver cancer and other diseases. Gut 1974;15:814–821

    Article  PubMed  CAS  Google Scholar 

  51. Okuda K, Kubo Y, Obata H: Serum a-fetoprotein in the relatively early stages of hepatocellular caricnoma and its relationship to gross anatomical types. Ann New York Acad Sci 1975;259:248–252

    Article  CAS  Google Scholar 

  52. Alpert E, Hutt MS, Davidson CS: Primary hepatoma in Uganda. A prospective clinical and epidemiologic study of forty-six patients. Am J Med 1969;46:794–802

    Article  PubMed  CAS  Google Scholar 

  53. Okuda K: Clinical aspects of hepatocellular carcinoma - analysis of 134 cases. In: Okuda K, Peters RL, eds. Hepatocellular carcinoma. Wiley, New York. 1976;387–436

    Google Scholar 

  54. Primack A, Vogel CL, Kyalwazi SK, et al: A staging system for hepatocellular caricnoma: Prognostic factors in Ugandan patients. Cancer 1975;35:1357–1364

    Article  PubMed  CAS  Google Scholar 

  55. Okuda K, Ohtsuki T, Obata H, et al: Natural history of hepato-cellular carcinoma and prognosis in relation to treatment. Study of 850 patients. Cancer 1985;56:918–928

    Article  PubMed  CAS  Google Scholar 

  56. Okuda K, Liver Cancer Study Group of Japan: Primary liver cancers in Japan. Cancer 1980;45:2663–2669

    Article  Google Scholar 

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  1. Chiba University School of Medicine, 1-8-1 Inohana, 280, Chiba, Japan

    Kunio Okuda M.D., Ph. D.

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  1. Kunio Okuda M.D., Ph. D.
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Okuda, K. Geographic heterogeneity of hepatocellular carcinoma. Gastroenterol Jpn 25, 787–792 (1990). https://doi.org/10.1007/BF02779198

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  • DOI: https://doi.org/10.1007/BF02779198

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