Summary
Effect of 2-deoxy-glucose (2-DG) on gastric blood flow was studied using square wave electromagnetic flow meter in dogs. Gastric blood flow started to increase after 2 min. of latent period and reached a peak 6 min. after 2-DG infusion, them decreased gradually.
Serum and tissue isotope activity were then studied using 2-DG-l-C14. Serum C14 activity rapidly decreased during the first 5 min. following the infusion, and the decrease then gradually continued. Tissue C14 activities including those in the hypothalamus and mycoardium revealed even distribution of C14 uptake. No tissue preference was proved.
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Fukushima, T., Ishiguro, N. & Tsuchiya, S. Effect of 2-deoxy-glucose on gastric blood flow. Gastroenterol Jpn 8, 331–337 (1973). https://doi.org/10.1007/BF02779110
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DOI: https://doi.org/10.1007/BF02779110