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Surgical experience with 5 n3(+) early gastric carcinoma cases

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Summary

Of 370 patients who underwent a resection for early gastric carcinoma, 317 (85.6%) were N(-), 28 n1(+), 20 n2(+) and five (1.4%) n3 respectively. In this study, n3(+) early gastric cancers were clinicopathologically evaluated and sites of the metastatic nodes were also difined. In addition, a comparative study in DNA ploidy patterns between primary and metastatic node cells was performed according to Hedley’s method using a FACS-IV scan of paraffin-embedded tissues. All n3(+) early gastric cancers showed an aneuploidy pattern. R2 or R3 operations are recommended for early gastric carcinomas with aneuploidy pattern and most of the metastatic nodes arise from the identical stem cell line of cancer cells.

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Authors and Affiliations

  1. First Department of Surgery, Nagasaki University School of Medicine, 852, Nagasaki, Japan

    Masao Tomita M.D., Hiroyuki Kusano, Tohru Nakagoe, Teruhisa Shimizu, Katsunobu Kawahara, Hiroyoshi Ayabe, Takatoshi Shimoyama & Toshio Miura

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  1. Masao Tomita M.D.
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  2. Hiroyuki Kusano
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  3. Tohru Nakagoe
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  4. Teruhisa Shimizu
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  5. Katsunobu Kawahara
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  6. Hiroyoshi Ayabe
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  7. Takatoshi Shimoyama
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  8. Toshio Miura
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Tomita, M., Kusano, H., Nakagoe, T. et al. Surgical experience with 5 n3(+) early gastric carcinoma cases. Gastroenterol Jpn 28, 374–378 (1993). https://doi.org/10.1007/BF02776981

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  • DOI: https://doi.org/10.1007/BF02776981

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