Summary
Plasma secretin levels were measured during a 72-hour starvation period in dogs. Plasma secretin rose significantly and insulin levels fell significantly during starvation. Intravenous glucose loading at the end of the 72-hour starvation period suppressed plasma secretin and free fatty acid levels with a concomitant rise of glucose and insulin levels. These findings suggest that secretin might be regulated by plasma glucose and insulin levels and might play a role in lipolysis during starvation.
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This research was supported in part by grant, Scientic Research B-62480282, from the Ministry of Education, Science and Culture, and grant from the Ministry of Health and Welfare of Japan.
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Manabe, T., Tanaka, Y., Yamaki, K. et al. The role of plasma secretin during starvation in dogs. Gastroenterol Jpn 22, 756–758 (1987). https://doi.org/10.1007/BF02776750
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DOI: https://doi.org/10.1007/BF02776750