Skip to main content

Advertisement

SpringerLink
Log in

Complications associated with ulcer recurrence following gastric surgery for ulcer disease

  • Review
  • Published:
Gastroenterologia Japonica Aims and scope Submit manuscript

Summary

The present study is an attempt to assess the risks of the complications associated with recurrent ulcers in patients who have undergone gastric surgery and to determine whether these risks differ from those observed in patients receiving long term maintenance treatment with H2-receptor antagonists for ulcer disease. One hundred and thirty studies reported in the literature during the past three decades have been analysed to determine both the approximate rate of ulcer recurrence and the proportion of patients with recurrent ulcers who have presented with either haemorrhage or perforation following the various types of gastric surgery for ulcer disease. From these data, estimates of the risks of haemorrhage and of perforation during the years following gastric surgery have been calculated. Vagotomy and antrectomy is associated with a low risk of ulcer recurrence (< 1%) and the risk of complications in later years is accordingly very small (< 0.5°/o). Partial gastrectomy, although associated with low recurrence rates, has a higher risk of complications (1.3% for haemorrhage, 0.3% for perforation) because the proportion of recurrent ulcers that present with haemorrhage or perforation is high (33% and 8%, respectively). Truncal vagotomy plus drainage (TV+D) and highly selective vagotomy (HSV) are associated with recurrence rates of 9% and 12%, respectively, but ulcer recurrences following these operations are less frequently accompanied by complications then recurrences after gastric resection and, as a result, the risks of haemorrhage (1.7% for TV+D; 1.3% for HSV) are similar to the risks after gastric resection. During long term (five years or more) maintenance treatment with H2-receptor antagonists, the risks of haemorrhage and perforation are < 2% and < 0.5%, respectively. It appears, therefore, that the likelihood of developing haemorhage or perforation following gastric surgery is of the same order as that during maintenance treatment with H2-receptor antagonists, at least during the first decade of follow-up.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Krause U: Long term results of medical and surgical treatment of peptic ulcer. Acta Chir Scand 1963;125 (Suppl 310):5-lll.

    Google Scholar 

  2. Krag E: Long term prognosis in medically treated peptic ulcer. Acta Med Scand 1966;180:657–668.

    Article  PubMed  CAS  Google Scholar 

  3. Hallenbeck G: The natural history of duodenal ulcer disease. Surg Clin North Am 1976;56:1235–1242.

    PubMed  CAS  Google Scholar 

  4. Pulvertaft CN: Incidence and natural history of gastric and duodenal ulcer. Postgrad Med J 1968;44:597–602.

    PubMed  CAS  Google Scholar 

  5. Fry J: Peptic ulcer: a profile. Br Med J 1964;2:809–812.

    CAS  PubMed  Google Scholar 

  6. Greibe J, Bugge P, Gjorup T, et al: Long term prognosis of duodenal ulcer: follow up study and survey of doctor’s estimates. Br Med J 1977;2:1572–1574.

    PubMed  CAS  Google Scholar 

  7. Penston JG: Natural history of duodenal ulcer disease. Scand J Gastroenterol 1990;25 (Suppl 177): 1–7.

    Article  Google Scholar 

  8. Stolte JB: Gross bleeding from the digestive tract. II. The frequency of manifest bleeding in peptic ulcer, with regard to the duration of the disease and the age of the diseased. Acta Med Scand 1944; 116:584–593.

    Article  Google Scholar 

  9. Viskum A: A comparison of the course of the disease among patients with gastric ulcer, duodenal ulcer, and ulcer dyspepsia without ulcer demonstrable by X-ray. Dan Med Bull 1976;23:129–136.

    PubMed  CAS  Google Scholar 

  10. Elashoff JD, Van Deventer G, Reedy TJ, et al: Long term followup of duodenal ulcer patients. J Clin Gastroenterol 1983;5:509–515.

    PubMed  CAS  Google Scholar 

  11. Gustavsson S, Holmberg L, Nyren O, et al: Risk of serious complications in patients with duodenal or prepyloric ulcers. Gastroenterology 1990;98:A54 (Abstract).

    Google Scholar 

  12. Burland WL, Hawkins BW, Beresford J: Cimetidine treatment for the prevention of recurrence of duodenal ulcer: an international collaborative study. Postgrad Med J 1980;56:173–176.

    PubMed  CAS  Google Scholar 

  13. Berstad A, Aadland E, Carlsen E, et al: Maintenance treatment of duodenal ulcer patients with a single bedtime dose of cimetidine. Scand J Gastroenterol 1979;14:827–831.

    PubMed  CAS  Google Scholar 

  14. Sontag S, Graham DY, Belsito A, et al: Cimetidine, cigarette smoking and recurrence of duodenal ulcer. N Engl J Med 1984; 311:689–693.

    Article  PubMed  CAS  Google Scholar 

  15. Gudmand-Hoyer E, Jensen KB, Krag E, et al: Prophylactic effect of cimetidine in duodenal ulcer disease. Br Med J 1978;l:1095–1097.

    Google Scholar 

  16. Dronfield MW, Batchelor AJ, Larkworthy W, et al: Controlled trials of maintenance cimetidine treatment in healed duodenal ulcer: short and long term effects. Gut 1979;20:526–530.

    Article  PubMed  CAS  Google Scholar 

  17. Alstead EM, Ryan FP, Holdsworth CD, et al: Ranitidine in the prevention of gastric and duodenal ulcer relapse. Gut 1983;24:418–420.

    Article  PubMed  CAS  Google Scholar 

  18. Silvis SE: Results of the US ranitidine maintenance trials. Am J Med 1984;77 (Suppl 5B):33–38.

    PubMed  CAS  Google Scholar 

  19. Hovdenak N, Johansen J, Lange O, et al: Ranitidine in the treatment and prophylaxis of duodenal ulcer. Scand J Gastroenterol 1985;20 (Suppl 113):32 (Abstract).

    Google Scholar 

  20. Bianchi Porro G, Petrillo M: Long term prophylactic treatment with cimetidine in duodenal ulceration. Ital J Gastroenterol 1979; 11:181–183.

    Google Scholar 

  21. Hentschel E, Schutze K, Weiss W, et al: Effect of cimetidine treatment in the prevention of gastric ulcer: a one year double blind multicentre study. Gut 1983;24:853–856.

    Article  PubMed  CAS  Google Scholar 

  22. Kinloch JD, Pearson AJG, Woolf IL, et al: The effect of cimetidine on the maintenance of healing of gastric ulceration. Postgrad Med J 1984;60:665–667.

    PubMed  CAS  Google Scholar 

  23. Machell RJ, Cliclitira PJ, Farthing MJG, et al: Cimetidine in the prevention of gastric ulcer relapse. Postgrad Med J 1979;55:393–395.

    PubMed  CAS  Google Scholar 

  24. Barr GD, Kang JY, Canalese J, et al: A two year prospective controlled study of maintenance cimetidine in gastric ulcer. Gastroenterology 1983;85:100–104.

    PubMed  CAS  Google Scholar 

  25. Record CO: Maintenance treatment with ranitidine in peptic ulceration. In: Tytgat GN, ed. Ranitidine, the selective new H2-receptor antagonist. Theracom, Guildford, UK. 1982;20–24.

    Google Scholar 

  26. Walan A, Bianchi Porro G, Hentschel E, et al: Maintenance treatment with cimetidine in peptic ulcer disease for up to 4 years. Scand J Gastroenterol 1987;22:397–405.

    Article  PubMed  CAS  Google Scholar 

  27. Bardhan KD: Six years of continuous cimetidine treatment in peptic ulcer disease: efficacy and safety. Aliment Pharmacol Therap 1988;2:395–405.

    Article  CAS  Google Scholar 

  28. Penston JG, Wormsley KG: Efficacy and safety of long term maintenance therapy of duodenal ulcers. Scand J Gastroenterol 1989; 24:1145–1152.

    Article  PubMed  CAS  Google Scholar 

  29. Penston JG, Wormsley KG: Long term maintenance treatment of gastric ulcers with ranitidine. Aliment Pharmacol Therap 1990;4: 339–355.

    Article  CAS  Google Scholar 

  30. Bodemar G, Walan A: Maintenace treatment of recurrent peptic ulcer by cimetidine. Lancet 1978;l:403–407.

    Article  Google Scholar 

  31. Boyd EJS, Wilson JA, Wormsley KG: Safety of ranitidine maintenance treatment of duodenal ulcer. Scand J Gastroenterol 1984; 19:394–400.

    PubMed  CAS  Google Scholar 

  32. Penston JG: The effect of maintenance treatment with ranitidine on the complications of duodenal ulcer disease. Scand J Gastroenterol 1990;25 (Suppl 177):52–60.

    Article  Google Scholar 

  33. Jensen DM, You S, Jensen ME, et al: Randomized controlled study of ranitidine maintenance for patients with a recent severe duodenal ulcer haemorrhage. Gastroenterology 1990;98:A65 (Abtract).

    Google Scholar 

  34. Mignon M, Ruszniewski Ph, Pappo M, et al: Traitement des poussees ou traitement preventif des recidives dans maladie ulcereuse duodenale? Gastroenterol Clin Biol 1990; 14:732–738.

    PubMed  CAS  Google Scholar 

  35. Lewisohn R: The frequency of gastrojejunal ulcers. Surg Gynec Obstet 1925;40:70–76.

    Google Scholar 

  36. Stabile BE, Passaro E: Recurrent peptic ulcer. Gastroenterology 1976;70:124–135.

    PubMed  CAS  Google Scholar 

  37. Small WP: The recurrence of ulceration after surgery for duodenal ulcer. J Roy Coll Surg Edin 1964;9:255–278.

    Google Scholar 

  38. Walters W, Lynn TE: Billroth I and Billroth II operations. Arch Surg 1957;74:680–685.

    CAS  Google Scholar 

  39. Goligher JC, Pulvertaft CN, de Tombal FT, et al: Five-to eight-year results of Leeds/York controlled trial of elective surgery for duodenal ulcer. Br Med J 1968;ii:781–787.

    Google Scholar 

  40. McKeown KC: A prospective study of the immediate and longterm results of Polya gastrectomy for duodenal ulcer. Br J Surg 1972;59:849–868.

    Article  PubMed  CAS  Google Scholar 

  41. Howard RJ, Murphy WR, Humphrey EW: A prospective randomized study of the elective surgical treatment for duodenal ulcer: two-to ten-year follow up study. Surgery 1973;73:256–260.

    PubMed  CAS  Google Scholar 

  42. Postlethwaite RW: Five year follow-up results of operations for duodenal ulcer. Surg Gynae Obstet 1973;137:387–392.

    Google Scholar 

  43. Anyadiegwu II, Mawesa D: Stomal ulcer after Polya gastrectomy in Zairian patients. East Afr Med J1976;53:549–553.

    PubMed  CAS  Google Scholar 

  44. Postlethwaite RW: Retrospective study of operations for peptic ulcer. Surg Gynec Obstet 1979;149:703–708.

    Google Scholar 

  45. Dinbar A, Avigad I, Shafir R, et al: Long term results of subtotal gastrectomy for duodenal ulcer. World J Surg 1980;4:625–633.

    Article  PubMed  CAS  Google Scholar 

  46. Thompson JC, Wiener I: Evaluation of surgical treatment of duodenal ulcer: short and long term effects. Clin Gastroenterol 1984;13:569–600.

    PubMed  CAS  Google Scholar 

  47. Fischer AB: Twenty-five years after Billroth II gastrectomy for duodenal ulcer. World J Surg 1984;8:293–302.

    Article  PubMed  CAS  Google Scholar 

  48. Cox AG: Vagotomy and drainage procedures. The present position. Progress in Surgery 1970;8:45–68.

    PubMed  CAS  Google Scholar 

  49. Jordan PH, Condon RE: A prospective evaluation of vagotomypyloroplasty and vagotomy-antrectomy for treatment of duodenal ulcer. Ann Surg 1970;172:547–563.

    Article  PubMed  Google Scholar 

  50. Hoerr Ward SO, Ward JT: Late results of three operations for chronic duodenal ulcer: vagotomy-gastroenterostomy, vagotomyhemigastrectomy, vagotomy-pyloroplasty. Ann Surg 1972; 176: 403–411.

    Article  PubMed  CAS  Google Scholar 

  51. Berger T, Kock NG, Norberg PB: Truncal vagotomy with ‘antrectomy’ or pyloroplasty for duodenal ulcer. A five year follow up study. Acta Chir Scand 1972;138:499–504.

    PubMed  CAS  Google Scholar 

  52. Dwight RW, Schimmel EM, O’Hara ET, et al: Controlled study of the surgical treatment of duodenal ulcer. Am J Surg 1975;129: 374–379.

    Article  PubMed  CAS  Google Scholar 

  53. Johnston D, Goligher JC: Selective, highly selective, or truncal vagotomy? Surg Clin N Am 1976;56:1313–1334.

    PubMed  CAS  Google Scholar 

  54. Herrington JL: Truncal vagotomy with antrectomy. Surg Clin N Am 1976;56:1335–1347.

    PubMed  Google Scholar 

  55. Sawyers JL, Herrington JL: Perforated duodenal ulcer managed by proximal gastric vagotomy and suture plication. Ann Surg 1977;185:656–659.

    Article  PubMed  CAS  Google Scholar 

  56. Dorricott NJ, McNeish AR, Alexander-Williams J, et al: Prospective randomized multicentre trial of proximal gastric vagotomy or truncal vagotomy and antrectomy for chronic duodenal ulcer: interim results. Br J Surg 1978;65:152–154.

    Article  PubMed  CAS  Google Scholar 

  57. Hubert JP, Kiernan PD, Beahrs OH, et al: Truncal vagotomy and resection in the treatment of duodenal ulcer. Mayo Clin Proc 1980;55:19–24.

    PubMed  Google Scholar 

  58. Mulholland M, Morrow C, Dunn DH, et al. Surgical treatment of duodenal ulcer. A prospective randomized study. Arch Surg 1982; 117:393–397.

    PubMed  CAS  Google Scholar 

  59. Fiser WP, Wellborn JC, Thompson BW, et al: Age and morbidity of vagotomy with antrectomy or pyloroplasty. Am J Surg 1982; 144:694–699.

    Article  PubMed  CAS  Google Scholar 

  60. Koo J, Lam SK, Chan P, et al: Proximal gastric vagotomy, truncal vagotomy with drainage, and truncal vagotomy with antrectomy for chronic duodenal ulcer. Ann Surg 1983;197:265–271.

    Article  PubMed  CAS  Google Scholar 

  61. Nobles ER: Vagotomy and gastroenterostomy, 15-year follow up of 175 patients. The American Surgeon 1966;32:177–182.

    PubMed  Google Scholar 

  62. Eisenberg MM, Woodward ER, Carson TJ, et al: Vagotomy and drainage procedure for duodenal ulcer: The results of ten years’ experience. Ann Surg 1969;170:317–328.

    Article  PubMed  CAS  Google Scholar 

  63. Stempien SJ, Dagradi AE, Lee EH, et al: Status of duodenal ulcer patients ten years or more after vagotomy-pyloroplasty (V-P). Am J Gastroenterol 1971;56:99–108.

    PubMed  CAS  Google Scholar 

  64. Goligher JC, Pulvertaf CN, Irvin TT, et al: Five-to eight-year results of truncal vagotomy and pyloroplasty for duodenal ulcer. Br Med J 1972;1:7–13.

    PubMed  CAS  Google Scholar 

  65. Kennedy T, Connell AM, Love AHG, et al: Selective or truncal vagotomy: five year results of a double blind prospective randomized controlled trial. Br J Surg 1973;60:944–948.

    Article  PubMed  CAS  Google Scholar 

  66. Kronberg O, Madsen P: A controlled randomized trial of highly selective vagotomy versus selective vagotomy and pyloroplasty in the treatment of duodenal ulcer. Gut 1975;16:268–271.

    Article  Google Scholar 

  67. Brooke-Cowden GL: The first 15 years’ experience with vagotomy and drainage for duodenal ulcer at the Royal Prince Alfred Hospital, Sydney. Aust NZ J Surg 1976;46:112–115.

    CAS  Google Scholar 

  68. O’Leary JP, Woodward ER, Hollenbeck JI, et al: Vagotomy and drainage procedure for duodenal ulcer. The results of seventeen years’ experiennce. Ann Surg 1976;183:613–616.

    PubMed  CAS  Google Scholar 

  69. Goligher JC, Feather DB, Hall R, et al: Several standard elective operations for duodenal ulcer: Ten to 16 year clinical results. Ann Surg 1979;189:18–24.

    Article  PubMed  CAS  Google Scholar 

  70. Pemberton JH, Van Heerden JA: Vagotomy and pyloroplasty in the treatment of duodenal ulcertain. Mayo Clin Proc 1980;55:14–18.

    PubMed  CAS  Google Scholar 

  71. Smith G, Irving AD: Age at operation and results of truncal vagotomy and gastroenterostomy in the treatment of duodenal ulcer. Am J Surg 1981;101:325–335.

    Google Scholar 

  72. Geel C, Ruedi T, Kobler E: 17-Jahres-Resultate nach Vagotomie und Pyloroplastik. Schweiz Med Wochenschr 1983;113:570–571.

    PubMed  CAS  Google Scholar 

  73. Koffman CG, Nay DJ, Ganguli PC, et al: A prospective randomized trial of vagotomy in chronic duodenal ulceration: 4-year follow-up. Br J Surg 1983;70:342–345.

    Article  PubMed  CAS  Google Scholar 

  74. Cetti R, Danielsen BB, Nielsen CB, Reuther K: Ulcus duodeni behandlet med trunkal vagotomi og draenage. Ugeskr Laeger 1982;144:707–710.

    PubMed  CAS  Google Scholar 

  75. Hoffman J, Jensen H-E, Schultze S, et al: Prospective controlled vagotomy trial for duodenal ulcer: results after five years. Br J Surg 1984;71:582–585.

    Article  Google Scholar 

  76. Clark CG, Fresini A, Araujo JGC, Boulos PB: Proximal gastric vagotomy or truncal vagotomy and drainage for chronic duodenal ulcer? Br J Surg 1986;73:298–300.

    Article  PubMed  CAS  Google Scholar 

  77. Selking O, Krause U, Nilsson F, et al: Parietal cell vagotomy and truncal vagotomy as treatment of duodenal ulcer. A prospective randomized trial. Acta Chir Scand 1981;147:561–567.

    PubMed  CAS  Google Scholar 

  78. Hoffmann J, Jensen H-E, Christiansen J, et al: Prospective controlled vagotomy trial for duodenal ulcer. Ann Surg 1989;209: 40–45.

    Article  PubMed  CAS  Google Scholar 

  79. Kraft RO, Kirsch MM, Kittleson AC, et al: Metabolic studies in patients subsequent to selective gastric vagotomy. Surg Gynec Obstet 1965;120:472–474.

    PubMed  CAS  Google Scholar 

  80. Amdrup E, Jensen H-E: One hundred patients five years after selective gastric vagotomy and drainage for duodenal ulcer. Surgery 1973;74:321–325.

    PubMed  CAS  Google Scholar 

  81. Faxen A, Kewenter J, Stockbrugger R: Clinical results of parietal cell vagotomy and selective vagotomy with pyloroplasty in the treatment of duodenal ulcer. Two-year follow-up of a prospective randomized study. Scand J Gastroenterol 1978;13:741–745.

    PubMed  CAS  Google Scholar 

  82. Madsen P, Kronborg O: Recurrent ulcer 5–8 years after highly selective vagotomy without drainage and selective vagotomy with pyloroplasty. Scand J Gastroenterol 1980;15:193–199.

    PubMed  CAS  Google Scholar 

  83. Hojlund B, Madsen P: The clinical results of selective vagotomy and pyloroplasty six to nine years later. Dan Med Bull 1980;27: 164–167.

    PubMed  CAS  Google Scholar 

  84. Griffith CA: Long term results of selective vagotomy plus pyloroplasty. 12 to 17 year follow-up. Am J Surg 1980;139:608–615.

    Article  PubMed  CAS  Google Scholar 

  85. Lehmann L, Kerscher P, Franke S, et al: Die selektiv-proximale Vagotomie mit Pyloroplastik beim Gastroduodenalulcus-Ergebnisse nach 5–9 Jahren. Lagenbecks Arch Chir 1983;359: 53–63.

    Article  Google Scholar 

  86. Wastell C, Colin J, Wilson T, et al: Prospective randomized trial of proximal gastric vagotomy either with or without pyloroplasty in treatment of uncomplicated duodenal ulcer. Br Med J 1977;ii: 851–857.

    Google Scholar 

  87. Goligher JC, Hill GL, Kenny TE, et al: Proximal gastric vagotomy without drainage for duodenal ulcer: results after 5–8 years. Br J Surg 1978;65:145–151.

    Article  PubMed  CAS  Google Scholar 

  88. Jensen H-E, Amdrup E: Follow-up of 100 patients five to eight years after parietal cell vagotomy. World J Surg 1978;2:525–532.

    Article  PubMed  CAS  Google Scholar 

  89. Jordan PH: Our first 35 patients studied five years after parietal cell vagotomy. Arch Surg 1979;114;528–535.

    PubMed  Google Scholar 

  90. Liavag I, Roland M: A seven year follow up of proximal gastric vagotomy. Clinical results. Scand J Gastroenterol 1979; 14:49–56.

    Article  PubMed  CAS  Google Scholar 

  91. Nilseil K: Five to nine year results of selective proximal vagotomy with and without pyloroplasty for duodenal ulcer. Acta Chir Scand 1979;145:251–255.

    Google Scholar 

  92. Van Heerden JA, Kelly KA, Dozois RR, et al. Proximal gastric vagotomy. Initial experience. Mayo Clin Proc 1980;55:10–13.

    PubMed  Google Scholar 

  93. Dejgaard A, Madsen P, Thisted B: Proksimal gastrisk vagotomi versus selektiv vagotomi og pyloroplastik for ulcus duodeni. Resultaterne af an kontrolleret, randomiseret undersogelse 6 til 9 ar efter operation. Ugeskr Laeger 1980;142:1400–1402.

    PubMed  CAS  Google Scholar 

  94. Storey DW, Boulos PB, Ward MW, et al: Proximal gastric vagotomy after 5 years. Gut 1981;22:702–704.

    Article  PubMed  CAS  Google Scholar 

  95. Schultze S, Poulsen PE, Christiansen J: Parietalcellevagotomi for ulcus duodeni. En resultatsopgorelse hos 119 patienter 1–9 ar efter operation. Ugeskr Laeger 1982;144:710–713.

    Google Scholar 

  96. Muhe E, Muller C, Martinoli S, et al: Five year results of a prospective multicentre trial of proximal gastric vagotomy. In: Baron JH et al., eds. Vagotomy in Modern Surgical Practice. London: Butterworths, 1982;176–186.

    Google Scholar 

  97. de Miguel J: Late results of proximal gastric vagotomy without drainage for duodenal ulcer: 5–9 year follow-up. Br J Surg 1982; 69:7–10.

    Article  PubMed  Google Scholar 

  98. Elder JB, Ganguli PC, Koffman CC, et al: Randomized trial of elective highly selective or truncal vagotomy in chronic duodenal ulceration. Can J Surg 1983;26:119–122.

    PubMed  CAS  Google Scholar 

  99. Gorey TF, Lennon F, Herfernan SJ:Highly selective vagotomy in duodenal ulceration and its complications. A 12-year review. Ann Surg 1984;200:181–184.

    Article  PubMed  CAS  Google Scholar 

  100. Stoddard CJ, Johnson AG, Duthie HL: The four to eight year results of the Sheffield trial of elective duodenal ulcer surgeryhighly selective or truncal vagotomy? Br J Surg 1984;71:779–782.

    Article  PubMed  CAS  Google Scholar 

  101. Adami H-O, Enander L-K, Enskog L, et al: Recurrences 1 to 10 years after highly selective vagotomy in prepyloric and duodenal ulcer disease. Ann Surg 1984;199:393–399.

    Article  PubMed  CAS  Google Scholar 

  102. Muller C, Martinoli: Klinische Ergebnisse. In: Muller C, Martinoli S, eds. Die Proximal-selektive Vagotomie. Springer-Verlag, Berlin, Heidelberg, New York, Tokyo. 1985;61–100.

    Google Scholar 

  103. Graffner HO, Liedberg GF, Oscarson JEA: Parietal cell vagotomy in the surgical treatment of chronic duodenal, pyloric and prepyloric ulcer disease. Int Surg 1985;70:139–144.

    PubMed  CAS  Google Scholar 

  104. Rongere C, Mestier P, Martin P, et al: Les recidives ulcereuses apres vagotomie fundique pour ulcere duodenal. Ann Chir 1985; 39:233–242.

    PubMed  CAS  Google Scholar 

  105. Marceau P, Bourque RA, Piche P, et al: Long term results of hyperselective vagotomy for duodenal ulcer. Can J Surg 1986; 29:421–423.

    PubMed  CAS  Google Scholar 

  106. Easkog L, Rydberg B, Adami HO, et al: Clinical results 1–10 years after highly selective vagotomy in 306 patients with prepyloric and duodenal disease. Br J Surg 1986;73:357–360.

    Article  Google Scholar 

  107. Romeo G, Catania G, Basile F, et al: Long term results of highly selective vagotomy: a 12 year experience. Ital J Surg Sei 1986;16: 93–96.

    CAS  Google Scholar 

  108. Busman DC, Volovics A, Munting JDK: Recurrence rate after highly selective vagotomy. World J Surg 1988;12:217–223.

    Article  PubMed  CAS  Google Scholar 

  109. Macintyre IMC, Millar A, Smith AN, et al: Highly selective vagotomy 5–15 years on. Br J Surg 1990;77:65–69.

    Article  PubMed  CAS  Google Scholar 

  110. Blackett RL, Johnston D: Recurrent ulceration after highly selective vagotomy for duodenal ulcer. Br J Surg 1981;68:705–710.

    Article  PubMed  CAS  Google Scholar 

  111. Hollender LF, Meyer C, Rivaz Diez B, et al: Analytical study and long term results of 230 highly selective vagotomies for chronic duodenal ulcer. Int Surg 1983;68:317–321.

    PubMed  CAS  Google Scholar 

  112. Lunde O-C, Liavag I, Roland M: Recurrent ulceration after proximal gastric vagotomy for duodenal ulcer. World J Surg 1983;7: 751–756.

    Article  PubMed  CAS  Google Scholar 

  113. Paimela H, Ahonen J, Hockerstedt K, et al: Five year results of proximal gastric vagotomy. Ann Chir Gynaecol 1983;72:3–8.

    PubMed  CAS  Google Scholar 

  114. Kennedy T: Long term results of proximal gastric vagotomy. Can J Surg 1984;27:304–341.

    Google Scholar 

  115. Teichman RK, Coppeller WA, Kramling HJ, et al: Ten year results following proximal selective vagotomy in duodenal disease. Chirurg 1985;56:515–521.

    Google Scholar 

  116. Herrington JL, Davidson J, Sumway SJ: Proximal gastric vagotomy. Follow-up of 109 patients for 6–13 years. Ann Surg 1986; 204:108–113.

    Article  PubMed  Google Scholar 

  117. von Holstein CS, Graffner H, Oscarson J: One hundred patients ten years after parietal cell vagotomy. Br J Surg 1987;74:101–103.

    Article  Google Scholar 

  118. Vinz H, Reisig J, Klose P, et al: Das Rezidivulkus nach selektiv proximaler Vagotomie. Zschr Klin Med 1988;43:1525–1530.

    Google Scholar 

  119. Meisner S, Jorgensen LN, Jensen H-E: The Kaplan and Meier and the Nelson estimate for the probability of ulcer recurrence 10 and 15 years after parietal cell vagotomy. Ann Surg 1988;207: 1–3.

    Article  PubMed  CAS  Google Scholar 

  120. Raab M, Said S, Hilgers RD, et al: Long term results of highly selective vagotomy for the treatment of duodenal ulcer. Hepato-Gastroenterol 1989;36:357–362.

    CAS  Google Scholar 

  121. Everson TC, Allen MJ: Gastrojejunal ulceration. Arch Surg 1954;69:140–147.

    CAS  Google Scholar 

  122. Bondar GF, Yakimets WW, Williams TG, et al: Diagnosis and management of stomal ulcer. Can J Surg 1964;7:383–388.

    PubMed  CAS  Google Scholar 

  123. Wychulis AR, Priestley JT, Foulk WT: A study of 360 patients with gastrojejunal ulceration. Surg Gynec Obstet 1966;122:89–99.

    PubMed  CAS  Google Scholar 

  124. Thompson JE, Dailey TH: Recurrent ulceration after operation for peptic ulcer: results after gastroenterostomy, gastrectomy and vagotomy in 64 cases. Ann Surg 1966;163:704–712.

    Article  PubMed  CAS  Google Scholar 

  125. Condon JR, Tanner NC: Retrospective review of 208 proved cases of anastomotic ulcer. Gut 1968;9:438–441.

    Article  PubMed  CAS  Google Scholar 

  126. Cleator IGM, Holubitsky IB, Harrison RC: Anastomotic ulceration. Ann Surg 1974;179:339–351.

    Article  PubMed  CAS  Google Scholar 

  127. Lindenauer SM, Dent TL: Management of the recurrent ulcer. Arch Surg 1975;110:531–535.

    PubMed  CAS  Google Scholar 

  128. Neustein CL, Bushkin FL, Weinshelbaum El, et al: Reoperation for postsurgical peptic ulcer recurrence: appraisal of ten years’ experience. Ann Surg 1977;185:169–174.

    Article  PubMed  CAS  Google Scholar 

  129. Thompson BW, Read RC: Secondary operations for duodenal ulcer. Am J Surg 1977;134:758–762.

    Article  PubMed  CAS  Google Scholar 

  130. Elhadad A, Debesse B, Latarjet I, et al: Les echecs du traitement chirurgical de l’ulcere de Cruveilhier. A propos de 62 reinterventions. Ann Chir 1978;32:153–161.

    PubMed  CAS  Google Scholar 

  131. Bambach CP, Coupland GAE, Cumberland VH, et al: Surgery for recurrent peptic ulceration. Aust NZ J Surg 1978;48:141–147.

    CAS  Google Scholar 

  132. Tasse D, Choiniere L, Morgan S, et al: Recurrent duodenal ulcer. Can J Surg 1978;21:306–308.

    PubMed  CAS  Google Scholar 

  133. Koo J, Lam SK, Ong GB: Cimetidine versus surgery for recurrent ulcer after gastric surgery. Ann Surg 1982;195:406–412.

    Article  PubMed  CAS  Google Scholar 

  134. Schirmer BD, Meyers WC, Hanks JB, et al: Marginal ulcer: A difficult surgical problem. Ann Surg 1982;195:653–660.

    Article  PubMed  CAS  Google Scholar 

  135. Heppell J, Bess MA, Mcllrath DC, et al: Surgical treatment of recurrent peptic ulcer disease. Ann Surg 1983;198:1–4.

    Article  PubMed  CAS  Google Scholar 

  136. Sharaiha ZK, Smith JL, Cain GC, et al: Recurrent ulcers after gastric surgery: endoscopic localization to the gastric mucosa. Am J Gastroenterol 1983;78:269–271.

    PubMed  CAS  Google Scholar 

  137. Thirlby RC, Feldman M: Transthoracic vagotomy for postoperative peptic ulcer. Ann Surg 1985;201:648–653.

    Article  PubMed  CAS  Google Scholar 

  138. Balint JA, Cooper GW, Price ECV, et al: The management of anastomotic ulcer. Lancet 1957;2:551–555.

    Article  Google Scholar 

  139. Davey WW: The surgery of anastomotic ulceration. Ann Roy Coll Surg Edin 1959;24:277–302.

    CAS  Google Scholar 

  140. Nuboer JF: Recurrent ulceration after surgical treatment of gastroduodenal peptic ulcers. Ann Roy Coll Surg Eng 1961;28:303–320.

    PubMed  CAS  Google Scholar 

  141. Small WP, Smith AN, Ruckley CV, et al: The continuing problem of jejunal ulcer. Amer J Surg 1971;121:541–547.

    Article  PubMed  CAS  Google Scholar 

  142. Boles RS, Cassidy WJ, Jordan SM: Medical versus surgical management of the complication of hemorrhage of duodenal ulcers. Gastroenterology 1957;32:52–57.

    PubMed  Google Scholar 

  143. Proot L, Derom F, Van Bastelaere W: Transthoracic vagotomy for recurrent peptic ulcer after gastrectomy. Acta Chir Belg 1978; 77:351–354.

    PubMed  CAS  Google Scholar 

  144. Speranza V, Basso N, Lezoche E, et al: Management and long-term results in patients with two-thirds gastrectomy and stomal ulcer. Am J Surg 1981;141:105–109.

    Article  PubMed  CAS  Google Scholar 

  145. Holtermuller KH, Gronniger J, Herzog P, et al: Behandlung von Ulcera peptica jejuni mit Cimetidin oder einem Antacidum? Deutsch Med Wschr 1982;107:1800–1804.

    Article  PubMed  CAS  Google Scholar 

  146. Feifel G, Koller H: Das Ulcusrezidiv nach chirurgischer Therapie des Ulcus duodeni. Chirurg 1982;53:23–28.

    PubMed  CAS  Google Scholar 

  147. Lee C-H, P’eng F-K, Lui W-Y: The clinical aspect of retained gastric antrum. Arch Surg 1986;121:1181–1186.

    PubMed  CAS  Google Scholar 

  148. Rahn A, Borsch G: Residivulzera nach Magenresektion bei Billroth-II und Billroth-I-Magen. Unterschiedliche Verteilungsmuster. Med Klin 1988;83:503–506.

    CAS  Google Scholar 

  149. Steinberg DM, Green G, Toye DKM, et al: The accuracy of methods of diagnosis in patients with suspected recurrent ulcer after vagotomy. Aust NZ J Surg 1975;45:252–256.

    CAS  Google Scholar 

  150. Juler GL, Dagradi AE, Stempien SJ, et al: Evaluation of recurrent duodenal ulcer after vagotomy-pyloroplasty. Am J Surg 1976;132:243–246.

    Article  PubMed  CAS  Google Scholar 

  151. Johnson JA, Giercksy K-E: Operative treatment of recurrence after vagotomy and drainage for duodenal ulcer, gastric ulcer, and acid dyspepsia without ulcer. World J Surg 1977;l:493–496.

    Article  Google Scholar 

  152. de Miguel J: Gastric ulceration after vagotomy for duodenal ulcer. Br J Surg 1977;64:39–41.

    Article  PubMed  Google Scholar 

  153. Rossi RL, Dial PF, Georgi B, et al: A five to ten year follow up study of parietal cell vagotomy. Surg Gynec Obstet 1986;162: 301–306.

    PubMed  CAS  Google Scholar 

  154. Johnston D, Blackett RL: Recurrent peptic ulcers. World J Surg 1987;ll:274–282.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Ninewells Hospital & Medical School, DD1 9SY, Dundee, Scotland, UK

    J. G. Penston, E. J. S. Boyd & K. G. Wormsley M.D.

Authors
  1. J. G. Penston
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. J. S. Boyd
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. K. G. Wormsley M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Penston, J.G., Boyd, E.J.S. & Wormsley, K.G. Complications associated with ulcer recurrence following gastric surgery for ulcer disease. Gastroenterol Jpn 27, 129–141 (1992). https://doi.org/10.1007/BF02775076

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02775076

Key words

Search

Navigation