Summary
The distribution of G-cells in the gastric glands was studied quantitatively using the indirect immunoperoxidase method in 37 resected stomachs: 11 for esophageal cancer, 14 for gastric cancer, 4 for gastric ulcer, 7 for duodenal ulcer, and 1 for atypical epithelium.
G-cells were seen in the pyloric glands and in the pseudopyloric glands in the atrophic fundic gland area. No G-cells were found in the fundic glands or in the cardiac glands.
There was a significant correlation between the number of G-cells and the pyloric and/or pseudopyloric glandular tubes (p<0.01).
The number of G-cells per glandular tube was 1.9 ±0.5 in the pyloric glands and 1.2 ±0.4 in the pseudopyloric glands on the pyloric part of the atrophic fundic gland area. G-cells were rarely seen in the pseudopyloric glands on the cardiac part of the atrophic fundic gland area.
It is suggested that the pseudopyloric glands without G-cells in the cardiac region are akin to cardiac glands.
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Ohchi, T., Misumi, A. & Akagi, M. A study on the distribution of G-cells in human gastric mucosa. Gastroenterol Jpn 19, 41–52 (1984). https://doi.org/10.1007/BF02774645
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DOI: https://doi.org/10.1007/BF02774645