Summary
The F-P border and stain phenomenon of the gastric mucosa were investigated by the application of methylene blue dye spraying method in endoscopy to 105 asymptomatic control volunteers and the following results were obtained; 1. The pyloric metaplasia is observed in the fundic gland area from the twenties in age and becomes increasing in its number and more widely spreading from the lesser curvature to the anterior and/or posterior wall of the corpus with advancing age. 2. The intestinal metaplasia arises from the thirties in age. 3. The intestinal metaplasia is observed either in the pyloric gland area or following the pyloric metaplasia in the fundic gland area. 4. Histologically, the stain phenomenon of the gastric mucosa is closely related to the intestinal metaplasia. Then, methylene blue dye spraying method is reevaluated to be useful for a precise endoscopie diagnosis of intestinal metaplasia.
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Kohli, Y., Hattori, S., Kodama, T. et al. Endoscopic diagnosis of intestinal metaplasia in asymptomatic (control) volunteers. Gastroenterol Jpn 14, 14–18 (1979). https://doi.org/10.1007/BF02774599
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DOI: https://doi.org/10.1007/BF02774599