Summary
Sixteen years follow-up was performed in a male of long-standing alcohol indulgence who had an alcoholic liver disease at the outset, followed by alcoholic pancreatitis which progressed finally to pancreatic calcification. During this course, the abnormalities of endoscopic pancreatogram were unremittingly progressive, whereas exocrine and endocrine pancreatic dysfunction remained fluctuating, but ultimately deteriorated. In contrast functional and histological abnormalities of the liver were not progressive but returned toward normal.
The follow-up observations in this case suggest that some cases of typical alcoholic pancreatitis may have unremittingly progressive morphologic changes with fairly well reserved capacity of exocrine and endocrine pancreatic functions and their hepatic lesions may not be in paralell with pancreatic lesions.
Similar content being viewed by others
References
Sarles H: Proposal adopted unanimously by the participants of the symposium on pancreatitis at Marseiles, 1963. Bibl Gastroenterol 7:7, 1965
Ammann RW: Die Differentialdiagnose zwischen akut-reversibler und chronisch-progressiver Pankreatitis. Schweiz Med Wochenschr 98: 744, 1968
Nagata A, et al: A study of chronic pancreatitis by serial endoscopie pancreatography. Gastroenterology 81:884, 1981
Owens JL, et al: Pancreatic calcification: A late sequel in the natural history of chronic alcoholism and alcoholic pancreatitis. Ann Surg 147: 326, 1958
Oda M: The onset and natural course of chronic alcoholic pancreatitis. Gastroenterol Jpn 14: 628, 1979
Howard JM, et al: A clinical study of alcoholic pancreatitis. Surg Gynec Obst 113: 167, 1961
Kasugai T: Recent advances in the endoscopic retrograde cholangiopancreatography. Digestion 13: 76, 1975
Howard JM, et al: Correlation of the histologie observations and operative findings in patients with chronic pancreatitis. Surg Gynec Obst 132: 387, 1971
Sarles H: Alcoholism and pancreatitis. Scand J Gastroent 6: 193, 1971
Dutta SK, et al: Associated liver disease in alcoholic pancreatitis. Dig Dis 23: 618, 1978
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Nagata, A., Homma, T., Ueno, K. et al. Sixteen years follow-up of a patient with alcoholic pancreatitis: Serial findings of morphology and function on the pancreas and the liver. Gastroenterol Jpn 17, 368–373 (1982). https://doi.org/10.1007/BF02774584
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02774584