Summary
This study was conducted on 139 patients with liver cirrhosis with diffuse formation of the nodules on the liver surface demonstrated by peritoneoscopic examination. In all of these patients, the diagnosis had been established more than 5 years ago, and the cumulative survival rates were calculated by the life table method. The relationship between the survival rate and macroscopic findings on the surface of the liver was studied and the following conclusions were drawn.
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1)
The 5 and 10 year survival rates in patients with cirrhosis with swelling of the right lobe were as high as 71.2 and 53.4% respectively and were significantly higher than the corresponding figures of 30.0 and 12.7% in patients with cirrhosis with right lobe atrophy (p< 0.001).
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2)
The 5 year survival rate in patients with cirrhosis of the small nodular type with a predominance of nodules with diameters less than 3mm was as high as 70.6%. This was significantly higher than that in patients with cirrhosis of the medium and large nodular type with nodules measuring more than 3 mm in diameter where the 5 year survival rate was 36.0% (p< 0.001).
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3)
The 5 year survival rate in patients with cirrhosis of the narrow stromal type was as high as 61.4%, being significantly higher than that in patients with cirrhosis of the broad and mixed stromal type where the 5 year survival rate was 43.2% (p< 0.05).
The observation of the surface pattern of the liver by peritoneoscopy appears to be of great predictive value for the prognosis of liver cirrhosis.
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References
Cutler SJ, et al: Maximum utilization of the life table method in analyzing survival. J Chron Dis 8: 699–712, 1958
Ratnoff OD, et al: The natural history of Laennec’s cirrhosis of the liver. An analysis of 386 cases. Medicine 21: 207–268, 1942
Douglass BE, et al: Portal cirrhosis: An analysis of 444 ases with notes on modern methods of treatment. Gastroenterology 15: 407–425, 1950
Stone WD, et al: The natural history of cirrhosis. Experience with an unselected group of patients. Quart J Med 37: 119–132, 1968
Powell WJ, et al: Duration of survival in patients with Laennec’s cirrhosis. Influence of alcohol withdrawal, and positive effects of recent changes in general management of the disease. Am J Med 44: 406–420, 1968
Selmair H, et al: Die Lebenserwartung der dekompensierten Leberzirrhose. Münch Med Wschr 112: 1241–1244, 1970
Okazaki I, et al: Follow-up studies on 146 cases of liver cirrhosis. J Keio Med Soc 50: 445–458, 1973
Soloway RD, et al: Observer error and sampling variability in evaluation of hepatitis and cirrhosis by liver biopsy. Am J Dig Dis 16: 1082–1086, 1971
Bruguera M, et al: Comparison of the accuracy of peritoneoscopy and liver biopsy in the diagnosis of cirrhosis. Gut 15: 799–800, 1974
Fifth Pan-American Congress of Gastroenterology: Report of the board of classification of cirrhosis of the liver. Gastroenterology 31: 213–216, 1956
Popper H, et al: Histogenesis of hepatic cirrhosis studied by the three dimensional approach. Am J Path 31: 405–441, 1955
Gall EA: Posthepatitic, postnecrotic and nutritinal cirrhosis. Am J Path 36: 241–271, 1960
Galambos JT: Classification of cirrhosis. Am J Gastroenterol 64: 437–451, 1975
Anthony PP, et al: The morphology of cirrhosis: definition, nomenclature, and classification. Bull WHO 55: 521–540, 1977
Miyake J, et al: In Japanese, Acta Hepatologica Jpn 6: 177–182, 1965
Higuchi Y: Studies on pathophisiology of viral hepatitis and cirrhosis by means of peritoneoscopy. 1. Correlation between structures of liver surface and histological architectures in cirrhosis. Jpn J Gastroent 59: 855–866, 1962
Garceau AJ, et al: The natural history of cirrhosis. II. The influence of alcohol and prior hepatitis on pathology and prognosis. New Engl J Med 271: 1173–1179, 1964
Oda M, et al: Studies on the prognostic indices of hepatitis and cirrhosis of the liver. Saishin-Igaku 27: 64–71, 1972
Shimada Y: Part X, Survival rates. Evolution of cirrhosis from viral hepatitis; Peritoneoscopic observations. Ishiyaku Publishers, Inc., Tokyo, 1979, p 247–256
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Harihara, S., Monna, T. & Yamamoto, S. The prognostic value of peritoneoscopic findings in patients with liver cirrhosis. Gastroenterol Jpn 15, 379–384 (1980). https://doi.org/10.1007/BF02774311
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DOI: https://doi.org/10.1007/BF02774311