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Clinical study on gastric secretion with special reference to pepsin secretion

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Summary

The stimulating effect of AOC-tetragastrin, caerulein, Histalog and secretin on human gastric acid and pepsin secretion was studied in gastric ulcer patients. The pattern of gastric acid and pepsin secretion after the administration of caerulein was closely resembled to that of gastrin. Slight increase of pepsin secretion after gastrin or caerulein could be based on “wash-out” action caused by the increase of acid secretion after the stimulants. Stimulating effect on gastric pepsin secretion of histalog and secretin would be independent of gastric acid secretion.

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Authors and Affiliations

  1. 5th Department of Internal Medicine, Fukuoka University School of Medicine, Nanakuma, Nishi-ku, 814, Fukuoka, Japan

    Ken Ito M.D., Mikio Inoue M.D., Toshiyuki Noda M.D., Kazuo Kuwano M.D. & Hiroko Takeda M.D.

  2. 1st Department of Internal Medicine, Aichi Cancer Center Hospital, Nagoya, Japan

    Tatsuzo Kasugai M.D. & Hiroshi Sugiura

Authors
  1. Ken Ito M.D.
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  2. Mikio Inoue M.D.
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  3. Toshiyuki Noda M.D.
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  4. Kazuo Kuwano M.D.
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  5. Hiroko Takeda M.D.
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  6. Tatsuzo Kasugai M.D.
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  7. Hiroshi Sugiura
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Ito, K., Inoue, M., Noda, T. et al. Clinical study on gastric secretion with special reference to pepsin secretion. Gastroenterol Jpn 13, 13–20 (1978). https://doi.org/10.1007/BF02774149

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  • DOI: https://doi.org/10.1007/BF02774149

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