Therapeutic effect of chlorophyll-a in the treatment of patients with chronic pancreatitis
- 35 Downloads
34 cases were treated with chlorophyll-a infusion and fairly favorable effect was obtained in 23 cases and some favorable effect, in 9 cases.
The most disgusting symptom of pancreatitis, the abdominal pain disappeared in a week or so with infusion of 5–20 mg of chlorophyll-a per day for 1–2 weeks, in all the effective cases.
Patients have become well controlled by intermittent administration of chlorophyll-a, even when they had recurrences.
5 cases which had difficulty in the treatment by trasylol, were also successfully treated with chlorophyll-a.
In all the cases treated with chlorophyll-a, no unfavorable side-effect, such as of allergic, or photosensitive, or hepatotoxic nature, was hitherto observed.
Key Wordspancreatitis chlorophyll-a protease inhibitor
Unable to display preview. Download preview PDF.
- 1).Creutzfeldt W, Schmidt H: Aetiology and pathogénesis of pancreatitis (Current concepts). Scand J Gastroenterol 5 (Suppl. 6): 47–62, 1970Google Scholar
- 2).Elliott DW: Treatment of acute pancreatitis with albumin and whole blood. Arch Surg 75: 573, 1957Google Scholar
- 3).Tsukiyama Y: Present state of medical treatment of pancreatitis in clinical cases. Igakushoin Publ., Tokyo, 1970(in Jpn)Google Scholar
- 5).Oda T, Yokono O, Yoshida A, et al: The effect of chlorophyll-a in the treatment of pancreatitis. Nihon Iji Shimpo 2438, 1969 (in Jpn)Google Scholar
- 6).Oda T, Yokono O, Yoshida A, Miyake K, Iino S: On the successful treatment of pancreatitis with chlorophyll-a and inhibitory effects of its derivatives on trypsin and other protease activities in vitro. Gastroenterol Jpn 6:49, 1971Google Scholar
- 8).Sarles H: Proposal adopted unanimously by the participants of the symposium on pancreatitis at Marseilles, 1963. Bibl Gastroenterol 7: VII-VIII, 1965Google Scholar
- 9).Elliott W: The mechanism of benefit derived from concentrated human serum albumin in experimental acute pancreatitis. Surg Forum 5: 384, 1954Google Scholar
- 12).Muramatsu M, Fujii S: Inhibitory effects of Ωguanidino acid esters on trypsin, plasmin, thrombin and plasma kallikrein. J Biochem 64: 807, 1968Google Scholar
- 13).Fujii S: FOY and pancreatitis. Gendai Iryo 6: 955, 1974 (in Jpn)Google Scholar
- 14).Mann NS: Experimental acute hemorrhagic pancreatitis: Effect of chlorophyll-a. Gastroenterology 74: 1061, 1978Google Scholar
- 17).Mandai H, Tsurumi T, Harada H, et al: Remarkable effect of chlorophyll-a on a case with chronic relapsing pancreatitis. Gendai Iryo 6: 1017, 1974 (in Jpn)Google Scholar
- 18).Okano T, Narasaki M, Ueda H: Some experiences of chlorophyll-a in the treatment of pancreatitis. Gendai Iryo 6: 1025, 1974 (in Jpn)Google Scholar
- 19).Kawauchi H, Kamijima A, Namiki M: Therapeutic effects of chlorophyll-a against pancreatitis. Diagnosis and Treatment 59: 156, 1971 (in Jpn)Google Scholar
- 20).Kubo K, Harada Y, Abiko H, Iwatake T, Tamechika N: Experience of chlorophyll-a in the treatment of pancreatitis. Diagnosis and Treatment 66: 1100, 1978 (in Jpn)Google Scholar
- 21).Miyatake R, Yoshida S, Masujima T, Fujita S, Nakamura M, Shimizu T: Clinical experience of chlorophyll-a in the treatment of chronic pancreatitis. Diagnosis and Treatment 66: 1250, 1978 (in Jpn)Google Scholar
- 22).Yasuoka H, Takada M, Matsuoka Y, Ozaki N: Case report of severe acute pancreatitis treated with chlorophyll-a. Gendai Iryo 10: 1387, 1978 (in Jpn)Google Scholar
- 23).Yamamoto T, Koseki Y, Miyagawa F: Inhibitory effect of chlorophyll-a on the pancrease alpha-amylase activity. Medicine and Biology 91: 271, 1975 (in Jpn)Google Scholar
- 24).Yamamoto T, Miyagawa F: Inhibitory effect of chlorophyll-a on a pancreatic lipase. Medicine and Biology 92: 11, 1976 (in Jpn)Google Scholar
- 25).Miyagawa F, Noguchi T: Effect of pantethine and chlorophyll-a to the fatty liver induced with the carbon tetrachloride. The St Marianna Med J 6: 379, 1978Google Scholar
- 26).Yoshida A, Yokono O, Oda T: The effects of intravenously administered chlorophyll-a on naturally occurring serum protease inhibitors in rabbits, submitted for publication to Gastroenterol Jpn 61Google Scholar