Summary
Circulating alpha-1 acid glycoprotein level in cirrhotic patients was determined by radioimmunoassay, and was compared to the ones in normal subjects and chronic active hepatitis with sublobular necrosis.
Serum alpha-1 acid glycoprotein levels in liver cirrhosis (p< 0.001) and chronic active hepatitis with sublobular necrosis (p< 0.02) were significantly reduced comparing to the normal subjects, although any statistically significant difference was not observed between the formers.
In liver cirrhosis, the serum alpha-1 acid glycoprotein level correlated negatively with serum albumin concentration but neither with serum alpha-1 globulin fraction nor with Indocyanine green clearance rate.
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Arima, T., Motoyama, Y., Yamamoto, T. et al. Serum glycoproteins in the liver diseases IV. Alpha-1 acid glycoprotein level in liver cirrhosis. Gastroenterol Jpn 12, 43–46 (1977). https://doi.org/10.1007/BF02773624
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DOI: https://doi.org/10.1007/BF02773624