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Effects of TC7 associated to 32% dextran 70, heparin and carboxymethylcellulose in adhesion prevention in the rat

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Summary

Experimental studies on adhesion formation 90 days after laparotomy in the rat were done. Uterine horn adhesions after standardised procedures and trauma in a control group of 10 rats were compared with those obtained in six other 10-rat groups in whom heparin, carboxymethylcellulose (CMC), 32% dextran 70 and the fabric TC7 either alone or in various combinations were used at the time of laparotomy. Dextran 70 and CMC used on their own appeared to reduce adhesion formation but the improvement did not achieve statistical significance when compared with the control group. TC7 used alone had no, anti-adhesion effect; when used with CMC or dextran 70, TC7 did not enhance the anti-adhesion benefit conferred by either substance used on its own.

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Authors and Affiliations

  1. Department of Animal Pathology, University of Zaragoza, Zaragoza, Spain

    J. Ortega-Moreno

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  1. J. Ortega-Moreno
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Ortega-Moreno, J. Effects of TC7 associated to 32% dextran 70, heparin and carboxymethylcellulose in adhesion prevention in the rat. Arch Gynecol Obstet 253, 27–32 (1993). https://doi.org/10.1007/BF02770630

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  • DOI: https://doi.org/10.1007/BF02770630

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