Skip to main content
SpringerLink
Log in

A new sclerosant therapy for testicular hydrocele with aspiration and injection of OK-432

  • Published:
International Urology and Nephrology Aims and scope Submit manuscript

Abstract

Twenty patients with testicular hydrocele were treated with a new sclerosing therapy consisting of intrascrotal injection of OK-432 (group AStreptococcus pyogenes of human origin). The median observation period after treatment was 6 months (range 2–13 months). Eighteen patients required only one treatment. Two patients had recurrences and received repeat injection. There have been no serious side effects except for fever of 2–3 days' duration and local inflammatory reaction. Sclerotherapy with OK-432 is an efficient and easy method which can be recommended as a primary treatment for hydrocele.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Nash, J. R.: Sclerotherapy for hydrocele and epididymal cysts.Br. J. Surg., 68, 289 (1979).

    Article  Google Scholar 

  2. Nash, J. R.: Sclerotherapy for hydrocele and epididymal cysts: A five year study.Br. Med. J., 288, 1652 (1984).

    Article  CAS  Google Scholar 

  3. Macfarlane, J. R.: Sclerosant therapy for hydroceles and epididymal cysts.Br. J. Urol., 55, 81 (1983).

    Article  CAS  PubMed  Google Scholar 

  4. Hu, K., Khan, A. S., Gonder, M.: Sclerotherapy with tetracycline solution for hydrocele.Urology, 24, 572 (1984).

    Article  CAS  PubMed  Google Scholar 

  5. Badenoch, D. F., Fowler, C. G., Jenkins, B. H.: Aspiration and instillation of tetracycline in the treatment of testicular hydrocele.Br. J. Urol., 5, 172 (1987).

    Article  Google Scholar 

  6. Bullock, N., Thurston, A. V.: Tetracycline sclerotherapy for hydroceles and epididymal cysts.Br. J. Urol., 59, 340 (1987).

    Article  CAS  PubMed  Google Scholar 

  7. Hellstrom, P., Malinen, L., Kontturi, M.: Sclerotherapy for hydroceles and epididymal cysts with ethanolamine oleate.Ann. Chir. Gynaecol., 75, 51 (1986).

    CAS  PubMed  Google Scholar 

  8. Ishida, N., Hoshino, T.: A Streptococcal Preparation as a, Potent Biological Response Modifier OK-432. 2nd ed. Excerpta Medica, Amsterdam 1985, pp. 1–5.

    Google Scholar 

  9. Ishida, N., Hoshino, T.: A Streptococcal Preparation as a Potent Biological Response Modifier OK-432. 2nd ed. Excerpta Medica, Amsterdam 1985, pp. 26–47.

    Google Scholar 

  10. Oshimi, K., Wakasugi, H., Seki, H.: Streptococcal preparation OK-432 augments cytotoxic activity against an erythroleukemic cell line in humans.Cancer Immunol. Immunother. 9, 187 (1980).

    Article  Google Scholar 

  11. Talmadge, J. E., Herberman, R. B.: The preclinical screening laboratory: Evaluation of immunomodulatory and therapeutic properties of biological response modifiers.Cancer Treat. Rep., 70, 171 (1986).

    CAS  PubMed  Google Scholar 

  12. Torisu, M., Fujimura, T., Kato, M.: Successful immunotherapy of carcinomatous pleuritis and peritonitis by intracavitary injection of OK-432. In: Hoshino, T., Uchida, A. (eds.): Clinical and Experimental Studies in Immunotherapy. Excerpta Medica, Amsterdam 1983, pp. 99–112.

    Google Scholar 

  13. Nagao, K.: Studies on treatment of pleural carcinomatosis, with special reference to effect of OK-432.Chiba Med. J., 58, 345 (1982).

    Google Scholar 

  14. Lund, L., Bartolin, J.: Treatment of hydrocele testis with aspiration and injection of polidocanol.J. Urol., 147, 1065 (1992).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Urology, Nagoya University School of Medicine, Nagoya, Japan

    M. Yamamoto, H. Hibi & K. Miyake

Authors
  1. M. Yamamoto
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. Hibi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. K. Miyake
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yamamoto, M., Hibi, H. & Miyake, K. A new sclerosant therapy for testicular hydrocele with aspiration and injection of OK-432. Int Urol Nephrol 26, 205–208 (1994). https://doi.org/10.1007/BF02768288

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02768288

Keywords

Search

Navigation