Urolithiasis and phytotherapy


The effects of seven plants with suspected application to prevent and treat stone kidney formation (Verbena officinalis, Lithospermum officinale, Taraxacum officinale, Equisetum arvense. Arctostaphylos uva-ursi, Arctium lappa andSilene saxifraga) have been studied using female Wistar rats. Variations of the main urolithiasis risk factors (citraturia, calciuria, phosphaturia, pH and diuresis) have been evaluated. It can be concluded that beneficial effects caused by these herb infusions on urolithiasis can be attributed to some disinfectant action, and tentatively to the presence of saponins. Specifically, some solvent action can be postulated with respect to uric stones or heterogeneous uric nucleus, due to the basifying capacity of some herb infusions. Nevertheless, for all the mentioned beneficial effects, more effective and equally innocuous substances are well known.

This is a preview of subscription content, log in to check access.


  1. 1.

    Grases, F., Conte, A.: Urolithiasis, inhibitors and promoters.Urol. Res., 20, 86 (1992).

    PubMed  Article  CAS  Google Scholar 

  2. 2.

    Grases, F., Costa-Bauzá, A., March, J. G., Masárová, L.: Glycosaminoglycans, uric acid and calcium oxalate urolithiasis.Urol. Res., 19, 375 (1991).

    PubMed  Article  CAS  Google Scholar 

  3. 3.

    Garcia-Raja, A., Conte, A., Grases, F.: The origin and causes of struvite stones.Int. Urol. Nephrol., 23, 537 (1991).

    Article  Google Scholar 

  4. 4.

    Lerner, S. P., Gleeson, M. J., Griffith, D. P.: Infection stones.J. Urol., 141, 753 (1989).

    PubMed  CAS  Google Scholar 

  5. 5.

    Sadi, M. V., Saltzman, N., Feria, G., Gittes, R. F.: Experimental observations on dissolution of uric acid calculi.J. Urol., 134, 575 (1985).

    PubMed  CAS  Google Scholar 

  6. 6.

    Brown, W. E., Gregory, T. M., Furedi-Milhofer, H. J.: Computed phase diagrams for the system: sodium hydroxide-uric acid-hydrochloric acid-water.J. Crystal Growth, 83, 588 (1987).

    Article  CAS  Google Scholar 

  7. 7.

    Font, P.: Plantas Medicinales, el Dioscórides renovado, Labor, Barcelona, Spain 1983.

    Google Scholar 

  8. 8.

    Volák, J., Stodola, J., Servera, F.: Plantas Medicinales. Artia, Prague 1983.

    Google Scholar 

  9. 9.

    Marozenco, Z.: Spectrophotometric Determinations of Elements. John Wiley & Sons, New York 1976.

    Google Scholar 

  10. 10.

    Pesce, A. J., Kaplan, L. A.: Methods in Clinical Chemistry, C. V. Mosby, St. Louis 1987.

    Google Scholar 

  11. 11.

    Grases, F., March, J. G., Ramis, M., Costa-Bauzá, A.: The influence of Zea mays on urinary risk factors for kidney stones in rats.Phytotherapy Res., 7, 146 (1993).

    Article  Google Scholar 

  12. 12.

    Grases, F., Masárová, L., Costa-Bauzá, A., March, J. G., Prieto, R., Tur, A.: Effect of Rosa canina infusion and magnesium on the urinary risk factors of calcium oxalate urolithiasis.Planta Medica, 58, 509 (1992).

    PubMed  Article  CAS  Google Scholar 

Download references

Author information



Corresponding author

Correspondence to F. Grases.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Grases, F., Melero, G., Costa-Bauzá, A. et al. Urolithiasis and phytotherapy. International Urology and Nephrology 26, 507–511 (1994). https://doi.org/10.1007/BF02767650

Download citation


  • Uric Acid
  • International Urology
  • Calcium Oxalate
  • Herb Infusion
  • Calcium Citrate