International Urology and Nephrology

, Volume 26, Issue 5, pp 507–511 | Cite as

Urolithiasis and phytotherapy

  • F. Grases
  • G. Melero
  • A. Costa-Bauzá
  • R. Prieto
  • J. G. March


The effects of seven plants with suspected application to prevent and treat stone kidney formation (Verbena officinalis, Lithospermum officinale, Taraxacum officinale, Equisetum arvense. Arctostaphylos uva-ursi, Arctium lappa andSilene saxifraga) have been studied using female Wistar rats. Variations of the main urolithiasis risk factors (citraturia, calciuria, phosphaturia, pH and diuresis) have been evaluated. It can be concluded that beneficial effects caused by these herb infusions on urolithiasis can be attributed to some disinfectant action, and tentatively to the presence of saponins. Specifically, some solvent action can be postulated with respect to uric stones or heterogeneous uric nucleus, due to the basifying capacity of some herb infusions. Nevertheless, for all the mentioned beneficial effects, more effective and equally innocuous substances are well known.


Uric Acid International Urology Calcium Oxalate Herb Infusion Calcium Citrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Grases, F., Conte, A.: Urolithiasis, inhibitors and promoters.Urol. Res., 20, 86 (1992).PubMedCrossRefGoogle Scholar
  2. 2.
    Grases, F., Costa-Bauzá, A., March, J. G., Masárová, L.: Glycosaminoglycans, uric acid and calcium oxalate urolithiasis.Urol. Res., 19, 375 (1991).PubMedCrossRefGoogle Scholar
  3. 3.
    Garcia-Raja, A., Conte, A., Grases, F.: The origin and causes of struvite stones.Int. Urol. Nephrol., 23, 537 (1991).CrossRefGoogle Scholar
  4. 4.
    Lerner, S. P., Gleeson, M. J., Griffith, D. P.: Infection stones.J. Urol., 141, 753 (1989).PubMedGoogle Scholar
  5. 5.
    Sadi, M. V., Saltzman, N., Feria, G., Gittes, R. F.: Experimental observations on dissolution of uric acid calculi.J. Urol., 134, 575 (1985).PubMedGoogle Scholar
  6. 6.
    Brown, W. E., Gregory, T. M., Furedi-Milhofer, H. J.: Computed phase diagrams for the system: sodium hydroxide-uric acid-hydrochloric acid-water.J. Crystal Growth, 83, 588 (1987).CrossRefGoogle Scholar
  7. 7.
    Font, P.: Plantas Medicinales, el Dioscórides renovado, Labor, Barcelona, Spain 1983.Google Scholar
  8. 8.
    Volák, J., Stodola, J., Servera, F.: Plantas Medicinales. Artia, Prague 1983.Google Scholar
  9. 9.
    Marozenco, Z.: Spectrophotometric Determinations of Elements. John Wiley & Sons, New York 1976.Google Scholar
  10. 10.
    Pesce, A. J., Kaplan, L. A.: Methods in Clinical Chemistry, C. V. Mosby, St. Louis 1987.Google Scholar
  11. 11.
    Grases, F., March, J. G., Ramis, M., Costa-Bauzá, A.: The influence of Zea mays on urinary risk factors for kidney stones in rats.Phytotherapy Res., 7, 146 (1993).CrossRefGoogle Scholar
  12. 12.
    Grases, F., Masárová, L., Costa-Bauzá, A., March, J. G., Prieto, R., Tur, A.: Effect of Rosa canina infusion and magnesium on the urinary risk factors of calcium oxalate urolithiasis.Planta Medica, 58, 509 (1992).PubMedCrossRefGoogle Scholar

Copyright information

© Akadémiai Kiadó 1994

Authors and Affiliations

  • F. Grases
    • 1
  • G. Melero
    • 1
  • A. Costa-Bauzá
    • 1
  • R. Prieto
    • 1
  • J. G. March
    • 1
  1. 1.Department of ChemistryUniversity of Balaeric IslandsPalma de MallorcaSpain

Personalised recommendations