Abstract
The permeability of the blood-brain barrier in the brain-blood direction is examined in newborn rats with hyperthermic convulsions induced by exposure to infrared radiation. Impaired permeability of this barrier due to convulsions is characterized by increased serum concentration of glial fibrillary acidic protein. Dexason lowers the protein level, which confirms its stabilizing effect on the blood-brain barrier structure. The advantage of early dexason administration is shown.
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Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 123, No. 2, pp. 146–149, February, 1997
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Gurina, O.I., Ryabukhin, I.A., Anin, A.N. et al. Permeability of the blood-brain barrier in newborn rats with induced hyperthermic convulsions. Bull Exp Biol Med 123, 123–125 (1997). https://doi.org/10.1007/BF02766430
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DOI: https://doi.org/10.1007/BF02766430