Abstract
Objective
To study the neurotic manifestations in thalassemic adolescents as a consequence of long-term illness.
Methods
From July 2003, thirty six thalassemic adolescents and forty normal adolescents were selected with age ranging from 13 to 18, and with same socio economic status and family, background. Middlesex Hospital Questionnaire by Crown and Crisp [1996] was administered and Mann Whiteny ‘U’ test was employed to measure free-floating anxiety, phobia, somatic anxiety, obsession, depression, hysteria and total neuroticism score. An interview was conducted along with the questionnaire to detect the problems in depth. Parents of thalassemic adolescents were interviewed subsequently to realize the behavioral problems existing along with neuroticism.
Results
Thirty-six of thalassemic and all forty normal adolescents returned the questionnaires. The responses suggest a marked difference in total neuroticism score and all other variables except that of hysteria. The interview on parents of thalassemic adolescents exposed various behavioral problems in these adolescents.
Conclusions
Thalassemic adolescents were having higher scores in neuroticism. Some behavioral problems are also found to exist along with neurotic manifestations. There remains a need, to improve the management of thalassemia in terms of psychological aspects in order to improve the mental health of this group.
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References
Guasco G, La Mantia A, Cuniolo A. Psychological problems of thalassemic subjects.Pediatr Med Chir 1987 May–Jun; 9(3): 269–279.
Olsson CA, Bond L, Johnson MW, Forer DL, Boyce MF, Sawyer SM. Adolescent chronic illness: a qualitative study of psychosocial adjustment.Ann Acad Med Singapore 2003 Jan;32(1): 43–50.
Huurre TM, Aro HM. Long-term psychosocial effects of persistent chronic illness. A follow-up study of Finnish adolescents aged 16 to 32 years.Eur Child Adolesc Psychiatry 2002 Apr; 11(2): 85–91.
Meijer SA, Sinnema G, Bijstra JO, Mellenbergh GJ, Wolters WH. Coping styles and locus of control as predictors for psychological adjustment of adolescents with a chronic illness.Soc Sci Med 2002 May; 54(9): 1453–1461.
Crown, S, Crisp AH. A short clinical diagnostic self rating scale for psychoneurotic patients-the M.H.. Q. Brit. jnl of Psc, 1961; 112: 917.
Kokkonen J, Kokkonen ER. Prevalence of mental disorders in young adults with chronic physical diseases since childhood as identified by the Present State Examination and the CATEGO program.Acta Psychiatr Scand 1993; Apr 87(4): 239–243.
Phillips NK, Hammen CL, Brennan PA, Najman JM, Bor W. Early adversity and the prospective prediction of depressive and anxiety disorders in adolescents.J Abnorm Child Psychol 2005 Feb; 33(1): 13–24.
Matta AP, Moreira Filho PF. Depressive symptoms and anxiety in patients with chronic and episodic tension-type headache.Arq Neuropsiquiatr 2003 Dec; 64(4): 991–994. Epub 2004 Jan 6.
Manevich TM, Sokolova ED, Iakhno NN, Rogovina EG. Specifics of personality and mental status in children and adolescence with chronic tension-type headache.Zh Nevrol Psikhiatr Im S S Korsakova 2004; 104(2): 11–15.
McWilliams LA, Cox BJ, Enns MW. Mood and anxiety disorders associated with chronic pain: an examination in a nationally representative sample.Pain 2003 Nov 106(1–2): 127–133.
Christian B. Growing up with chronic illness: psychosocial adjustment of children and adolescents with cystic fibrosis.Annu Rev Nurs Res 2003; 21: 151–172.
Thomas J, Jones G, Scarinci I, Brantley P. A descriptive and comparative study of the prevalence of depressive and anxiety disorders in low-income adults with type 2 diabetes and other chronic illnesses.Diabetes Care 2003 Aug; 26(8): 2311–2317.
Moussa MA, Alsaeid M, Abdella N, Refai TM, Al-Sheikh N, Gomez JE. Social and psychological characteristics of Kuwaiti children and adolescents with type 1 diabetes.Soc Sci Med 2005 Apr;60(8): 1835–1844.
Thomas J, Jones G, Scarinci I, Brantley P. A descriptive and comparative study of the prevalence of depressive and anxiety disorders in low-income adults with type 2 diabetes and other chronic illnesses.Diabetes Care 2003 Aug;26(8): 2311–2317.
Moussa MA, Alsaeid M, Abdella N, Refai TM, Al-Sheikh N, Gomez JE. Social and psychological characteristics of Kuwaiti children and adolescents with type 1 diabetes.Soc Sci Med 2005 Apr; 60(8): 1835–1844.
Akechi T, Nakano T, Uchitomi Y. Scientific background of psycho-oncology.Seishin Shinkeigaku Zasshi 2004; 106(6): 764–771.
Hayward C, Wilson KA, Lagle K, Killen JD, Taylor CB: Parent-reported predictors of adolescent panic attacks.J Am Acad Child Adolesc Psychiatry 2004 May; 43(5): 613–620.
Asmundson GJ, Norton GR, Jacobson SJ. Social, blood/injury, and agoraphobic fears in patients with physically unexplained chronic pain: are they clinically significant?Anxiety 1996; 2(1) 28–33.
Manevich TM, Sokolova ED, Iakhno NN, Rogovina EG. Specifics of personality and mental status in children and adolescence with chronic tension-type headache.Zh Nevrol Psikhiatr Im S S Korsakova 2004; 104(2): 11–15.
DeWit DJ, Ogborne A, Offord DR, MacDonald K. Antecedents of the risk of recovery from DSM-III-R social phobia.Psychol Med 1999 May; 29(3): 569–582.
Schonweiler R, Neuschulte C, Paar GH. Illness behavior and depression in tinnitus patients.Laryngorhinootologie 1989 May; 68(5): 267–270.
Monsen K, Havik OE. Psychological functioning and bodily conditions in patients with pain disorder associated with psychological factors.Br J Med Psychol 2001 Jun; 74(Pt 2): 183–195.
Goldbeck L, Baving A, Kohne E. Psychosocial aspects of beta-thalassemia: distress, coping and adherence.Klin Padiatr 2000 Sep–Oct; 212(5): 254–259.
Aydin B, Yaprak I, Akarsu D, Okten N, Ulgen M. Psychosocial aspects and psychiatric disorders in children with thalassemia major.Acta Paediatr Jpn 1997 Jun; 39(3): 354–357.
Bush S, Mandel PS, Gairdina PJ. Future orientation and life expectations of adolescents and young adults with thalassemia major.Ann N Y Acad Sci 1998 Jun 30; 850: 361–369.
Rachman, S.J.. Obsesional-Compulsive checking. Behavioural Research and Therapy, 1976; 14:269–277.
Wells A. Meta-cognition and worry. Behavioural and Cognitive Psychotherapy. 1995 23: 301–20.
Crews WD Jr, Jefferson AL, Broshek DK, Rhodes RD, Williamson J, Brazil AM, Barth JT, Robbins MK. Neuropsychological dysfunction in patients with end-stage pulmonary disease: lung transplant evaluation.Arch Clin Neuropsychol 2003 May; 18(4): 353–362.
Modrego PJ, Pina MA, Galindo M, Minguez J. Study of psychopathology in patients with chronic non-lesional epilepsy: a Minnesota multiphasic personality inventory profile controlled study.Eur Neurol 2002; 48(2): 80–86.
Michelotti A, Martina R, Russo M, Romeo R. Personality characteristics of temporomandibular disorder patients using M.M.P.I..Cranio 1998 Apr; 16(2): 119–125.
Blakely AA, Howard RC, Sosich RM, Murdoch JC, Menkes DB, Spears GF. Psychiatric symptoms, personality and ways of coping in chronic fatigue syndrome.Psychol Med 1991 May; 21(2): 347–362.
Berghuis JP, Heiman JR, Rothman I, Berger RE. Psychological and physical factors involved in chronic idiopathic prostatitis.J Psychosom Res 1996 Oct; 41(4): 313–325.
Invernizzi G, Gala C, Buono M, Cittone L, Tavola T, Conte G. Neurotic traits and disease duration in headache patients.Cephalalgia 1989 Sep; 9(3): 173–178.
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Moorjani, J.D., Issac, C. Neurotic manifestations in adolescents with thalassemia major. Indian J Pediatr 73, 603–607 (2006). https://doi.org/10.1007/BF02759926
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DOI: https://doi.org/10.1007/BF02759926