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Chemical reactions catalyzed by DNA polymerases

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Abstract

Chemical reactions catalyzed by various DNA polymerases are discussed, including DNA chain extension, the 3′→5′-exonuclease proofreading activity, and some other pathways of replicative repair. The contribution of DNA polymerases to the fidelity of the template-dependent synthesis is analyzed by the examples of some most typical DNA polymerases.

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  1. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, ul. Vavilova 32, 117984, Moscow, GSP-1, Russia

    A. A. Krayevsky

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  1. A. A. Krayevsky
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Deceased.

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Krayevsky, A.A. Chemical reactions catalyzed by DNA polymerases. Russ J Bioorg Chem 26, 2–8 (2000). https://doi.org/10.1007/BF02758854

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