Skip to main content
SpringerLink
Log in

Wilson's disease presenting as respiratory failure

  • Clincial Brief
  • Published:
The Indian Journal of Pediatrics Aims and scope Submit manuscript

Abstract

Wilson's disease in an 11-year-old girl with generalized weakness and respiratory failure is reported. The child succumbed to severe hypokalemia refractory to therapy progressing to acute renal failure and death. This atypical presentation and course prompted this clinical brief.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Chu CC, Huang CC, Chu NS. Recurrent hypokalemic muscle weakness as an initial manifestation of Wilson's disease.Nephron 1996; 73(3): 477–479.

    PubMed  CAS  Google Scholar 

  2. MCH Division, Department of Family Welfare, Ministry of Health and Family Welfare, New Delhi, India.Surveillance of Acute Flaccid Paralysis. 2nd edn. 2000: 22–23, 35

  3. Bearn AG, Yu TF, Gutman Ab. Renal function in Wilson's disease.J Clin Invest 1957; 36: 1107–1114.

    Article  PubMed  CAS  Google Scholar 

  4. Reynolds ES, Tannen RI, Tyler HR: The renal lesion in Wilson's disease.Am J Med 1966; 40: 518–527.

    Article  Google Scholar 

  5. Leu ML, Strickland Gt, Gutman RA. Renal function in Wilson's disease: Response to Penicillamine therapy.Am J Med Sci 1970; 260: 381–398.

    Article  PubMed  CAS  Google Scholar 

  6. Fulop M, Sternlieb I, Scheinberg IH. Defective urinary acidification in Wilson's disease.Ann Intern Med 1968; 68: 770–777.

    PubMed  CAS  Google Scholar 

  7. Sternlieb I, Bennett B, Scheinberg IH. D-Penicillamine induced Goodpasture's syndrome in Wilson's disease:Ann Intern Med 1975; 82: 673–676.

    PubMed  CAS  Google Scholar 

  8. Pandit A, Bavdekar A, Bhave S. Wilson's disease.Indian J Pediatr 2002; 69: 785–791.

    Article  PubMed  Google Scholar 

  9. Kalra V, Khurana D, Mittal R. Wilson's disease—Early onset and lessons from a pediatric cohort in India.Indian Pediatr 2000; 37: 595–601.

    PubMed  CAS  Google Scholar 

  10. Sinha S, Jha DK, Sinha KK. Wilson's Disease in Eastern India.J Assoc Physicians India 2001; 49: 881–884.

    PubMed  CAS  Google Scholar 

  11. Tannen RL. Potassium disorders. In Kokko JP, Tannen RL, eds.Fluids and electrolytes. 3rd edn. Philadelphia; W.B. Saunders Company, 1996; 127–129.

    Google Scholar 

  12. Nadel SM, Jackson JW, Ploth DW. Hypokalemic Rhabdomyolysis and Acute renal failure. Occurrence following total parenteral nutrition.JAMA 1979; 241: 2294–2296.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Deaprtment of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), 605 006, Pondicherry

    P. Narayanan, G. Chetan & S. Mahadevan (Professor)

Authors
  1. P. Narayanan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. Chetan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. S. Mahadevan
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to S. Mahadevan.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Narayanan, P., Chetan, G. & Mahadevan, S. Wilson's disease presenting as respiratory failure. Indian J Pediatr 73, 99–100 (2006). https://doi.org/10.1007/BF02758271

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02758271

Key words

Search

Navigation