Skip to main content
Log in

Neurological complications of congenital heart disease

  • Symposium: Pediatric Cardiology
  • Published:
The Indian Journal of Pediatrics Aims and scope Submit manuscript

Abstract

Neurological complications contribute significantly to mortality and morbidity from congenital heart disease with serious long-term consequences. Congenital heart disease has also been shown to adversely influence the neuro-developmental outcome of children. In developing countries such as India, majority of congenital heart defects remains uncorrected and major neurological complications are frequently encountered. Stroke and brain abscess are the commonest neurological complications of unoperated congenital heart disease.

In developed countries the focus has now shifted to neurological complications of cardiac surgery in the very young as a result of cardiopulmonary bypass and total hypothermic circulatory arrest. A variety of neurological disturbances are now being increasingly recognized and are currently the subject of intense investigations. In this review the neurological complications of uncorrected congenital heart disease and the common neurological complications that result from operations for congenital heart disease will be discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Fyler D. Report of the New England Regional Cardiac Program.Pediatrics 65: S375–S461.

  2. Hoffman JIE. Reflections on the past, present and future of pediatric cardiology.Cardiol Young 1994; 4: 208–223.

    Google Scholar 

  3. O’Dougherty, Wright FS, Loeweson RB, Torres F. Cerebral dysfunction after chronic hypoxia in children.Neurology 1985; 35(1): 42–46.

    PubMed  CAS  Google Scholar 

  4. Benson D. Changing profile of congenital heart disease.Pediatrics 1989; 83(5): 790–791.

    PubMed  Google Scholar 

  5. Ghosh S, Chandy MJ, Abraham J. Brain abscess and congenital heart disease.J Indian Med Assoc 1990; 88(11): 312–314.

    PubMed  CAS  Google Scholar 

  6. Newburger J, Silbert A, Buckley Let al. Cognitive function and age at repair of transposition of great arteries in children.N Engl J Med 1984; 310: 1495–1499.

    Article  PubMed  CAS  Google Scholar 

  7. Gilles, Levinton A, Jammes B. Age-dependent changes in white matter in congenital heart disease.J Neuropathol Exp Neurol 1973; 32: 179.

    Google Scholar 

  8. Ammash N, Warnes CA. Cerebrovascular events in adult patients with cyanotic congenital heart disease.J Am Coll Cardiol 1996; 28(3): 768–772.

    PubMed  CAS  Google Scholar 

  9. Ratnasiri B. Ten year review of brain abscess in Children’s Hospital Bangkok, Thailand.J Med Assoc Thai 1995; 78(1): 37–41.

    Google Scholar 

  10. Takeshita M, Kagawa M, Yonetani Het al. Risk factors for brain abscess in patients with congenital cyanotic heart disease.Neurol Med Chir (Tokyo) 1992; 32(9): 667–670.

    CAS  Google Scholar 

  11. Newburger J, Jonas R, Wernovsky Get al. A comparison of the perioperative neurologic effects of hypothermic circulatory arrest versus low-flow cardiopulmonary bypass in infant heart surgery.N Engl J Med 1993; 329: 1057–1064.

    Article  PubMed  CAS  Google Scholar 

  12. Clarkson P, Macarthur B, Barrat-Boyes Bet al. Developmental progress after cardiac surgery in infancy using deep hypothermia and circulatory arrest.Circulation 1980; 62: 855–861.

    PubMed  CAS  Google Scholar 

  13. Du Plessis A, Trves S, Hickey Pet al. Regional cerebral perfusion abnormalities after cardiac operations.J Thorac Cardiovasc Surg 1990; 107: 1036–1043.

    Google Scholar 

  14. Gooch J, Suchyta MM, Balbierz Jet al. Prolonged paralysis after treatment with neuromuscular junction blocking agents.Crit Care Med 1991; 19(9): 1125–1131.

    Article  PubMed  CAS  Google Scholar 

  15. Robinoson R, Samuels M, Pohl K. Choreic syndromes after cardiac surgery.Arch Dis Child 1988; 63: 1466–1469.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Krishna Kumar.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kumar, K. Neurological complications of congenital heart disease. Indian J Pediatr 67, 287–291 (2000). https://doi.org/10.1007/BF02758175

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02758175

Key words

Navigation