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Acute dapsone poisoning in a child

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Summary

A child with acute DDS poisoning has been presented. The main features were severe cyanosis, and acute neurotoxicity with diffuse central nervous system involvement. Therapy directed towards accelerated urinary excretion of the drug by promoting diuresis and conversion of reduced to oxidised hemoglobin was successful in saving the life of the child. The child was quite normal on follow-up examination three months later.

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Author information

Author notes

  1. K. M. Saxena (Associate Director of Medical Education in Pediatrics)

    Present address: Children’s Hospital, St. Paul, Minnesota, USA

Authors and Affiliations

  1. New Delhi

    K. M. Saxena (Associate Director of Medical Education in Pediatrics) & A. K. Pathak

Authors
  1. K. M. Saxena
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  2. A. K. Pathak
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Additional information

From the department of Pediatrics, Maulana Azad Medical College and Irwin Hospital, New Delhi-1.

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Saxena, K.M., Pathak, A.K. Acute dapsone poisoning in a child. Indian J Pediatr 34, 367–371 (1967). https://doi.org/10.1007/BF02756913

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  • DOI: https://doi.org/10.1007/BF02756913

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