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Bone changes in acute leukaemia

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Summary

Two cases of leukaemia, one acute myeloid and the other acute lymphatic, with bone changes are described. The bone changes included a band of metaphyseal rarefaction, destructive areas, generalised osteoporosis and subperiosteal ossification. The skull was involved in one case. No ossification changes were found. The literature is reviewed.

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References

  • Aisner, M. and Hoixe, T. B. (1948). Bone and joint pain in leukaemia simulating acute rheumatic fever and subacute bacterial endocarditis.New Engl. J. Med. 238, 733.

    Article  PubMed  CAS  Google Scholar 

  • Baty, J. M. and Vogt, E. C. (1935). Bone changes in leukaemia in children.Amer. J. Roentgenol. 34, 310.

    Google Scholar 

  • Bedwell, C. A. and Dawson, A. M. (1954). Chronic myeloid leukaemia in a child presenting as acute polyarthritis.Arch. Dis. Childh. 29, 78.

    PubMed  CAS  Google Scholar 

  • Caffey, J. (1961). Pediatric X-ray Diagnosis, Page 1092.Year Book Publishers, Chicago.

    Google Scholar 

  • Craver, L. F. and Copeland, M. M. (1935). Changes of bone in leukaemia.Arch. Surg. 30, 369.

    Google Scholar 

  • Dale, J. H. Jr. (1949). Leukaemia in childhood: A clinical and roentgenographic study of 72 cases.J. Pediat. 34, 421.

    Article  PubMed  Google Scholar 

  • Ghei, O. P., Khetrapal, S. K. and Walia, B. N. S. (1962). Leukaemia in childhood.Indian J. Pediat. 29, 405.

    Article  Google Scholar 

  • Griffiths, D. Ll. (1955). Bone changes and blood diseases, in Modern Trends in Blood Disease, Editor J. F. Wilkinson, page 1,Butterworth, London.

    Google Scholar 

  • Hansman, C. F. and Girdany, B. R. (1957). The roentgenographic findings associated with neuroblastoma.J. Pediat. 51, 621.

    Article  PubMed  CAS  Google Scholar 

  • Heschl, R. (1855) Cited by Griffiths (1955).

    Google Scholar 

  • Heuck, J. (1879). Cited by Griffiths (1955).

    Google Scholar 

  • Hildebrand, H. (1950). Leukaemia of spine in children.Fortschr. Geb. Rontgenstrahlen,72, 709.

    Article  CAS  Google Scholar 

  • Kalayjian, B. S., Herbut, P. A. and Erf, L. A. (1946). Bone changes of leukaemia in children.Radiology,47, 223.

    Google Scholar 

  • Lightwood, R., Barrie, H. and Butler, N. (1960). Observations on 100 cases of leukaemia in childhood.Brit. med. J. 1, 747.

    PubMed  CAS  Google Scholar 

  • Metcalfe, R. H. (1951). Cited by Griffiths (1955).

    Google Scholar 

  • Neumann, E. (1878). Cited by Griffiths (1955).

    Google Scholar 

  • Pugh, D. G. (1956). In Diagnostic Roentgenology, Editor R. Golden.William and Wilkins, Baltimore.

    Google Scholar 

  • Schlesinger, B. (1949). Cited by Griffiths (1955).

    Google Scholar 

  • Silverman, F. N. (1948). Skeletal lesions in leukaemia: clinical and roentgen observations in infants and children with review of the literature.Amer. J. Roentgenol. 59, 819.

    CAS  Google Scholar 

  • Smith, C. H. (1933). Leukopenic myeloid leukaemia associated with arthritis.Amer. J. Dis. Child. 46, 123.

    Google Scholar 

  • Smith, C. H. (1935). Leukaemia in childhood with onset simulating rheumatic disease.J. Pediat. 7, 390.

    Article  Google Scholar 

  • Snelling, C. E. and Brown, A. (1934). Bone changes in leukaemia: Clinical and roentgenological study.Arch. Dis. Childh. 9, 315.

    Article  Google Scholar 

  • Svab, V. and Horak, B. (1951). Cited by Willson (1959).

    Google Scholar 

  • Udani, P. M. (1961). Clinical manifestations of leukaemia in children.Indian. J. Chld. Hlth. 10, 169.

    Google Scholar 

  • Willson, J. K. V. (1959). Bone changes in childhood leukaemia, survey of 140 cases.Radiology,72, 672.

    PubMed  CAS  Google Scholar 

  • Windholz, F. and Foster, J. E. (1949). Cited by Griffiths (1955).

    Google Scholar 

  • Wollstein, M. (1932). Cited by Griffiths (1955).

    Google Scholar 

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From the Department of Pediatrics, G.S.V.M. Medical College, Kanpur.

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Garg, B.K. Bone changes in acute leukaemia. Indian J Pediatr 34, 245–249 (1967). https://doi.org/10.1007/BF02756293

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  • DOI: https://doi.org/10.1007/BF02756293

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