References
Comblath M, Reisner S H: Blood glucose in the neonate and its clinical significance. N. Engl J Med 273:378, 1965
Wybregt S H, Reisner S H, Patel R K, et al: The incidence of neonatal hypoglycemia in a nurseryl for premature infants. J Pediatr 64:796, 1964.
Baens G S, Lundeen, D, Cornblath, M.: Studies of carbohydrate metabolism in the newborn infant. VI. Levels of glucose in blood in premature infant. Pediatrics 31:580, 1963
Lubchenco L O, Bard H: Incidence of hypoglycemia in newborn linfants classified by birth weight and gestational Tage. Pediatrics 47:831, 1971
Koivisto M, Blanco-Sequeiros M, Krause U: Neonatal symptomatic and asymptomatic hypoglycaemia : A follow-up study of 151 children. Develop Med Child Neurol 14:603, 1972
Cornblath M, Schwartz R: Disorders of carbohydrate metabolism in infancy. W.B. Saunders Company, Philadelphia, 1976, Pg-72
Pagliara A S, Karl I E, Haymond M et al: Hypoglycemia in infancy childhood. Part I. J Pediatr 82:365, 1973
Cornblath M, Pildes R A., Schwartz R: Hypoglycemia in infancy and childhood. J Pediatr, 83: 692, 1973
Kalhan S C, D’ Angelo L J, Savin S M, Adam, P.A. J.: Glucose production in pregnant women at term gestation. J Clin Invest 63: 388, 1979
Widdas W F: Instability of diffusion to account for placental glucose transfer in the sheep and consideration of the kinetics of a possible carrier transfer. JJ Physiol 118 : 23, 1952
Young M: Placental transfer Of glucose and amino acids in early diabetes in early life. Edited by Camerini F A, Devalos M, Cole H S Academy Press, Inc., New York 1975
Kauer F, Joyce J: The influence of high maternal plasma glucose levels and maternal blood glow on the placental transfer of glucose in the guinea pig. Diabetologia 9:453, 1973
Whaley W H, Zuspan F P, Nelson A, et al: Correlation between maternal and fetal plasma levels of glucose and free fatty acids. Am J Obstet & Gynecol. 94:419, 1966
Marsac D, Saundubray A M, Moncion A, et al: Development of gluconeogenic enzymes in the liver of human newborns. Biol Neonate 28 : 317, 1976
Raiha NCR, Lindros K O: Development of some enzymes involved in gluconeogenesis in human liver. Ann Med Exp Biol Fenn 47 : 145, 1969
Villee C A: The intermediary metabolism of human fetal tissues, Cold Spring Harbor Symp. Quart Biol 19:186, 1954
Schwartz A I, Rail T W: Hormonal regulation of incorporation of alanine-U-C into glucose in human fetal liver expiants, D iabetes 24 : 650, 1975
Adam P A J, Schwartz A L, Rahiala E L et al: Glucose production in midterm human fetus. I, Autoregulation of glucose uptake. Am J Physiol 234 : 560, 1978
Robinson F H: Development of gluconeogenic enzymes in the newborn guinea pig. Biol Neonate 29 :48, 1976
Arinze IJ: Development of phosphoenoldyruvate carboxykinase and gluconeogenesie in guinea pig liver, Biochem Biophys Res Commun 65: 184, 1975
Jones C T, Ashton I K: The appearance, properties, and functions of gluconeogenic enzymes in the liver and kidney of the guinea pig during fetal and early neonatal development. Arch Biochem Biophys 174 : 506, 1976
Warnes D M, Seamark R F: Metabolism of glucose, fructose, and lactate in vivo in chronically cannulated fetuses and suckling Iambs. Biochem J 162 : 617, 1977
Warnes D M, Seamark R F: The appearance of gluconeogenesis at birth in sheep. Biochem J 162 : 627, 1977
Adam P A J, Felig P : Carbohydrate, fat, and amino acid metabolism in the pregnant woman and fetus, Fdited by Ealkner F., and Tanrer J M Human Growth 1 :461, 1978
Adam P A J, King K C, Schwartz R, Teramo K: Human placental barrier to 1–125 glucapon early in gestation. J Clin Endocrinol & Metab 34 : 772, 1972
King K C, Adam P A J, Schwartz, R., Teramo, K: Human placental transfer of human growth hormone 1–125. Pediatrics 48 : 534, 1971
Kalhan S C, Schwartz R, Adam P A J: Placental bairier to human insulin 1–125 in insulin-dependent diabetic mothers. J Clin Endocrinol & Metab 40 : 139, 1975
Adam P A J, Teramo K Raiha N, et al: Human fetal insulin metabolism early in gestation. Response to acute elevation of the fetal glucose concentration and placental transfer of hyman insulin 1–131. Diabetes 18 : 409, 1969
King K C, Butt J, Ravio T K, et al: Human maternal and fetal insulin response to arginine. N Engl J Med 285: 607, 1971
Obenshain S S, Adam P A J, King K C, et al: Human fetal insulin response to sustained maternal hyperglycemia. N Engl J Med 283: 566, 1970
Grajwer L A, Sperling M A, Sack J, et al: Possible mechanisms and significance of the neonatal surge in glucagon secretion: Studies in newborn lambs. Pediatr Res 11:833, 1977
Lagercrantz H, Bistoletti P: Catecholamine release in the newborn infant at birth. Pediatr Res 11:889, 1973
Kalhan SC, Savin S M, Adam PA J:Measurement of glucose turnover in the human newborn with glucose-1-13C. J. Clin. Endocrinol 6 metab 43:704, 1976
King K C, Tserng, K Y, Kalhan SC : Regulation of glucose production in newborn infants of diabetic mothers. Pediatr Res 1982 (in press)
Adam P A J, Raiha N, Rahiala E-L, et al: Oxidation of glucose and D-B-OH-Butyrate by the early human fetal brain. Acta Paediatr Scand 64:17, 1975
Metzger B E and Freinkel N: Effects of diabetes mellitus on endocrinologic and metabolic adaptations of gestation. Edited by Merkatz I R, and Adam p A J The Diabetic Pregnancy. Grune & Stratton, New York, pg. 23, 1979
Adam P A J, Kalhan SC, Savin S : Fuel metabolism in the infant of the diabetic mother: Attenuated mobilization of alternate fuels. Edited by New, M I, and Fiser, R H Diabetes & Other Endocrine Disorders During Pregnancy & in the Newborn. Alan R Liss, Inc., New York, rg. 51, 1976
Persson B, Gentz J, KelJum M: Metabolic observations in infants of strictly controlled diabetic mothers. Plasma levels of glucose, FPA, glycerol, and D-B-hydroxybutyrate during the first two hours after birth. Acta Paediatr Scand 62:465, 1973
Adam P A J: Infant of a diabetic mother : Energy imbalance between adipose tissue and liver. Edited by Merkatz, L R and Adam, P A J The Diabetic Pregnancy. Grune & Stration, New York, pg. 175, 1979
Kalban S C, Savin S M, Adam P A J: Attenuated glucose production rate in newborn infants of insulin-dependent diabetic mothers. N Engl J Med 296:375, 1977
Bloom S R, Johnston D I: Failure of glucagon release in infants of diabetic mothers. Br Med J 4:453, 1972
Stern L, Ramos A, Leduc J: Urinary catecbolamine excretion in infants of diabetic mothers. Pediatrics 43:598, 1968
Senterre J, KarJberg P: Respiratory quotient and metabolic rate in normal full-term and small-for-date newborn infants. Acta Paediatr Scand 59:653, 1970
Schwartz R, Adam P A J, King K, et al: Glucose control in the newborn infant. Nutricia Symposium: Aspects of Prematurity and (Dysmaturity. Edited by Jonxis J H P, Visser H K A, and Travelstra J A, pg. 211, 1968
Gentz J C M, Warmer R, Persson B F M, et al: Intravenous glucose tolerance, plasma insulin, free fatty acids, and B-hydroxybutyrate in underweight newborn infants. Acta Pediatr Scand 58:481, 1969
Haymond M W, Karl I E, Pagliara A S, Increased gluconeogenic substrates in the small-for-gestational-agej infant. N Engl J Med 291:322, 1974
Aynsley-Green A: Clinical metabolic, and endocrine aspects of neonatal hyperinsulinism due to nesidioblastosis of the pancreas. Edited by Adreani, D, Lefebvre, P J, and Marks, V Current Views on Hypoglycemia and Glucagon. Academic Press, London, pg. 379, 1980
Heitz P U, Kloppel G, Polak, J M: Morphology of the endocrine pancrease in persistent hypoglycemia in infants. Edited by Andreani D, Lefebvre P G, and Marks V : Current Views on Hypoglycemia and. Glucagon. Academic Press, London, pg 335, 1980
Johnson J D, Hansen R C, Albrittor W L, et al: Hypoplasia of the anterior pituitary and neonatal hypoglycemia. J Pediatr 82: 634, 1973
Lovinger R D, Kaplan S L, Grumbach M M: Congenital hypopitutarism associated with neonatal hypoglycemia and microcephalus; Four cases secondary to hypothalamic hormone deficiencies. J Pediatr 87:1171, 1975
LaFranchi S, Buist II R M, Thaveri B, et al: Amino acids as substrates in children with growth hormone deficiency and hypoglycemia Pediatrics 68:260, 1981
Polak J M, Bloom S R: Somatostin deficiency in presistent neonatal hyperinsulcen ia. Edited by Mark V, and Andreani D Current Views on Hypoglycemia and Glucagon. Academic Press, London, pg. 367, 1980
Stanley C A, Baker L: Hyperinsulinism in infancy: Diagnosis by demonstration of abnormal response to fasting hypoglycemia. Pediatrics 57 : 702, 1976
Lilien L D, Pildes R S, Srinivasan, G., et al: Treatment of neonatal hypoglycemia with minibolus and intravenous glucose infusion J Pediatr 97: 295, 1980.
Anderson J M., Milner RDG, Strich SJ: Pathological changes in the nervous system in severe neonatal hypoglycemia. Lancet 11: 372, 1966
Blattner RJ. Central nervous system damage and hypoglycemia. J Pediatr 72:904, 1968
Chase HP, Marlow RA, Dabiere BS, et al: Hypoglycemia and brain development. Pediatncs 52 :513, 1973
Pildes RS, Cornblath M., Wurren I, et al: A prospective controlled study of neonatal hypoglvcemia. Pediatrics 54 : 5, 1974
Agardh C D, Balimo H., Oisson Y, et al: Hypoglycemic brain injury : Metabolic and structural findings in rat cerebellar cortex during profound insulin-induced hypoglybemic and in the recovery perioe following glucose administration. J Cerebral Blood Flow & Tetabo 1 : 71, 1981
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King, K.C. Hypoglycemia in newborn infants. Indian J Pediatr 49, 715–726 (1982). https://doi.org/10.1007/BF02752660
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DOI: https://doi.org/10.1007/BF02752660