Abstract
Serum IgG, IgM, IgA, IgG subclasses (IgG1, G2, G3, G4), isohemagglutinins and complement-3 concentrations were measured in 23 beta-thalassemic patients suffering from recurrent infections. No significant abnormalities were found in these humoral immunity investigations, both in splenectomized and non-splenectomized patients. On the other hand, iron overload or repeated blood transfusions were not found to down-regulate the humoral immune system of thalassemic patients.
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Vergin, C., Kutukculer, N., Cetingul, N. et al. Serum immunoglobulins, IgG subclasses, isohemagglutinins and complement-3 levels in patients with thalassemia major. Indian J Pediatr 64, 215–219 (1997). https://doi.org/10.1007/BF02752450
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DOI: https://doi.org/10.1007/BF02752450