Skip to main content
Log in

Hemostatic profile in septicemic neonates with and without bleeding

  • Original Articles
  • Published:
The Indian Journal of Pediatrics Aims and scope Submit manuscript

Abstract

Hemostatic profile was studied in 25 full term, non-asphyxiated neonates with blood culture-proven septicemia. Nine (36%) of these neonates manifested bleeding. Detailed coagulation tests and platelet studies were deranged in 24 (96%) of neonates with septicemia. Abnormalities in coagulation tests did not differ in those with and without bleeding. Only platelet aggregation with ADP was deranged to a significantly greater extent in those with bleeding as compared with those without bleeding.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Dacie JV, Lewis SM. Hemostatic mechanism. In: Lewis SM, ed.Practical Hematology, 2nd ed. London; Churchill Livingstone, 1963; pp 208–216.

    Google Scholar 

  2. Dacie JV, Lewis SM. Hemostatic mechanism and coagulation factors. In: Lewis SM, ed.Practical Hematology, 6th ed, London; Churchill Livingstone, 1984; pp 208–247.

    Google Scholar 

  3. Cronkite B. Morphology and enumeration of human platelets.J Appl Physiol 1950; 3: 365–368.

    PubMed  Google Scholar 

  4. Borchgrevinck CF. A method for measuring platelet adhesivenessin vivo.Acta Med Scand 1960; 168 (3): 157–164.

    Article  Google Scholar 

  5. Hardisty RM, Ingram GIC. Platelet tests. In: Ingram GIC, ed.Bleeding Disorders—Investigation and Management. 2nd ed. Oxford; Blackwell Scientific Publications, 1965; pp 269–287.

    Google Scholar 

  6. Zucker MB, Borrelli J. Platelet clumping produced by connective tissue suspensions by collagen.Proc Soc Exp Bio and Med 1962; 109: 779–787.

    Google Scholar 

  7. Hardisty RM, Hutton RA. The kaolin clotting time of PRP—A test of Pf 3 a.Br J Hematol 1965; 11: 258–267.

    CAS  Google Scholar 

  8. Corrigan JJ, Ray WL, May N. Changes in the blood coagulation system associated with septicemia.N Engl J Med 1968; 279 (16): 851–856.

    Article  PubMed  Google Scholar 

  9. Dube B, Das BK, Bhargava V. Hemostatic changes in neonates with anoxia and sepsis.Indian Pediatr 1989; 26: 26–31.

    PubMed  CAS  Google Scholar 

  10. Bhargava SK, Kumari S, Bhargava M. Impairment of platelet function in neonatal septicemia.Indian J Med Res 1978; 68: 964–969.

    PubMed  CAS  Google Scholar 

  11. Wintrobe MM, Lee GR, Boggs DR. Diffuse intravascular coagulation. In: Wintrobe MM, Lee RR, Boggs DR, eds.Clinical Hematology. 8th ed. Philadelphia; Lea & Febriger 1981: pp 1213–1227.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Alamelu, V., Dutta, A.K., Narayan, S. et al. Hemostatic profile in septicemic neonates with and without bleeding. Indian J Pediatr 59, 407–410 (1992). https://doi.org/10.1007/BF02751549

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02751549

Key words

Navigation