Lipid adsorption/absorption on polycarbonate surfaces — an understanding

Abstract

Thrombus formation on a foreign surface is a complicated process, involving many factors. The adhesion and aggregation of platelets play an important role in the initial events of thrombus formation on such surfaces. In this work, adsorption/absorption studies using saturated fatty acids were carried out on polycarbonate surface to evaluate how such surfaces may affect blood-polymer interaction. The surface change was investigated by measuring the interfacial energies as derived from advancing contact angle technique. The plasma recalicification time and platelet adhesion studies were also carried out to further develop an understanding.