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The bag cell neurons ofAplysia

A model for the study of the molecular mechanisms involved in the control of prolonged animal behaviors

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Abstract

Egg laying inAplysia involves a well-characterized series of behaviors that can last for several hours. The behaviors are controlled by two bilateral clusters of peptidergic neurons in the abdominal ganglion. Following brief stimulation, these neurons, which have been termed the bag cell neurons, undergo a sequence of changes in their excitability lasting many hours. The bag cell neurons have served as a model system for studying the molecular mechanisms involved in the synthesis, processing, and release of neuroactive peptides and in the regulation of prolonged changes in neuronal excitability.

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  1. Department of Pharmacology, Emory University School of Medicine, 30322, Atlanta, GA

    P. Jeffrey Conn

  2. Departments of Pharmacology and Cellular and Molecular Physiology, Yale University School of Medicine, 333 Cedar Street, 06510, New Haven, CT

    Leonard K. Kaczmarek

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Conn, P.J., Kaczmarek, L.K. The bag cell neurons ofAplysia . Mol Neurobiol 3, 237–273 (1989). https://doi.org/10.1007/BF02740607

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