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Endocrine Pathology

, Volume 8, Issue 1, pp 75–80 | Cite as

Epithelial cyst of thyroid

  • Catherine J. StreutkerEmail author
  • David Murray
  • Kalman Kovacs
  • Hubert P. Higgins
Case Report

Abstract

A benign thyroid cyst lined by thyroid follicular epithelial cells lacking immunoreactivity to thyroglobulin is reported. The patient had a 3 yr history of a large cyst in the lateral anterior neck, with no symptoms of hyperthyroidism or hyperparathyroidism. Water-clear fluid was repeatedly aspirated; analysis indicated the absence of parathyroid hormone (PTH), T3, and T4. Hemithyroidectomy revealed a simple epithelial cyst. Such cysts are rare, comprising approx 1% of thyroid nodules. A differential diagnosis of cystic neck lesions is presented and the possible pathogenesis of this cyst is discussed.

Key Words

Epithelial cyst thyroid pathology 

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References

  1. 1.
    Cusick EL, McIntosh CA, Krukowski ZH, Matheson NA. Cystic change and neoplasia in isolated thyroid swellings. Br J Surg 75:982,983, 1988.PubMedCrossRefGoogle Scholar
  2. 2.
    Hammer M, Wortsman J, Folse R. Cancer in cystic lesions of the thyroid. Arch Surg 117:1020–1023, 1982.PubMedGoogle Scholar
  3. 3.
    Crile G Jr, Hawk WA Jr. Aspiration biopsy of thyroid nodules. Surg Gynecol Obstet 136:241–245, 1973.PubMedGoogle Scholar
  4. 4.
    Crile G Jr. Treament of thyroid cysts by aspiration. Surgery 59:210–212, 1966.PubMedGoogle Scholar
  5. 5.
    Rosen IB, Provias JP, Walfish PG. Pathologic nature of cystic thyroid nodules selected for surgery by needle aspiration biopsy. Surgery 100:606–612, 1986.PubMedGoogle Scholar
  6. 6.
    Miskin M, Rosen IB, Walfish PG. B-Mode ultrasonography in assessment of thyroid gland lesions. Ann Int Med 79:505–510, 1973.PubMedGoogle Scholar
  7. 7.
    de los Santos ET, Keyhani-Rofagha S, Cunningham JJ, Mazzaferri EL. Cystic thyroid nodules; the dilemma of malignant lesions. Arch Intern Med 150:1422–1427, 1990.PubMedCrossRefGoogle Scholar
  8. 8.
    Simeone JF, Daniels GH, Mueller PR, Maloof F, van Sonnenberg E, Hall DA, O'Connell RS, Ferrucci RS Jr, Wittenberg J. High resolution real-time sonography of the thyroid. Radiology 145:431–435, 1982.PubMedGoogle Scholar
  9. 9.
    McHenry CR, Walfish PG, Rosen IB Non-diagnostic fine needle aspiration biopsy: a dilemma in management of nondular thyroid disease. Am Surgeon 59:415–419, 1993.PubMedGoogle Scholar
  10. 10.
    Jennings AS. Nonisotopic techniques of thyroid imaging. In: Braverman LE, Utiger RD, eds. Werner and Ingbar's The thyroid, a fundamental and clinical text. 6th ed. New York, NY, J. B. Lippincott, 1996; 525–543.Google Scholar
  11. 11.
    Blum M. Ultrasonography and computed tomography of the thyroid gland. In: Ingbar SH, Braverman LE, eds. Werner's The thyroid, a fundamental and clinical text. 5th ed. New York, NY, J. B. Lippincott, 1986; 576–591.Google Scholar
  12. 12.
    Kovacs K, Stefaneanu L, Horvath E, Lloyd RV, Lancranjan I, Buchfelder M, Fahlbusch R. Effect of dopamine agonist medication on prolactin producing pituitary adenomas. Virchows Arch A Pathol Anat 418:39–46, 1991.CrossRefGoogle Scholar
  13. 13.
    Clark OH, Okerlund MD, Cavalieri RR, Greenspan FS. Diagnosis and treatment of thyroid, parathyroid and thyroglossal duct cysts. J Clin Endo Metab 48:983–988, 1979.CrossRefGoogle Scholar
  14. 14.
    Rehak NN, Oertel YC, Herp A, Chiang BT, Csako G. Biochemical analysis of thyroid cyst fluid obtained by fine-needle aspiration. Arch Pathol Lab Med 117:625–630, 1993.PubMedGoogle Scholar
  15. 15.
    Miller JM, uz Zafar S, Karo JJ. The cystic thyroid nodule: recognition and management. Radiology 110:257–261, 1974.PubMedGoogle Scholar
  16. 16.
    Ginsberg J, Young JEM, Walfish PG. Parathyroid cysts; medical diagnosis and management. JAMA 240:1506,1507, 1978.PubMedCrossRefGoogle Scholar
  17. 17.
    Crile GJ Jr, Perryman RG. Parathyroid cysts; a report of five cases. Surgery 34:151–154, 1953.PubMedGoogle Scholar
  18. 18.
    Katz AD, Dunkleman D. Needle aspiration of nonfunctioning parathyroid cysts. Arch Surg 119:307,308, 1984.PubMedGoogle Scholar
  19. 19.
    Alvi A, Myssiorek D, Wasserman P. Parathyroid cyst: current diagnostic and management principles. Head Neck 18:370–373, 1996.PubMedCrossRefGoogle Scholar
  20. 20.
    Som PM, Sacher M, Lanzieri CF, Solodnik P, Cohen BA, Reede DL, Bergeron ST, Biller HF. Parenchymal cysts of the lower neck. Radiology 157:399–406, 1985.PubMedGoogle Scholar
  21. 21.
    Shareef DS, Salm R. Ectopic vestigial lesions of the neck and shoulders. J Clin Pathol 34:1155–1162, 1981.PubMedCrossRefGoogle Scholar
  22. 22.
    Harnsberger HR, Mancuso M, Muraki AS, Byrd SE, Dillon WP, Johnson LP, Hanafee WN. Branchial cleft anomalies and their mimics: computed tomographic evaluation. Radiology 152:739–748, 1984.PubMedGoogle Scholar
  23. 23.
    Simons JN, Robinson DW, Masters FW. Cervical thymic cyst. Am J Surg 108:578–582, 1964.PubMedCrossRefGoogle Scholar
  24. 24.
    Mikal S. Cervical thymic cyst; case report and review of the literature: Arch Surg 109:558–562, 1974.PubMedGoogle Scholar
  25. 25.
    Silverman PM, Korobkin M, Moore AV. Case report; CT diagnosis of cystic hygroma of the neck. J Comput Assist Tomogr 7:519–520, 1983.PubMedGoogle Scholar
  26. 26.
    Som PM, Zimmerman RA, Biller HF. Cystic hygroma and facial nerve paralysis: a rare association. J Comput Assist Tomogr 8:110–113, 1984.PubMedGoogle Scholar
  27. 27.
    Tovi F, Zirkin H. Solitary lateral cervical cyst: presenting symptom of papillary thyroid adenocarcinoma. Ann Otol Rhinol Laryngol 92:521–524, 1983.PubMedGoogle Scholar
  28. 28.
    Cinberg JZ, Silver CE, Molnar JJ, Vogl SE. Cervical cysts: cancer unitil proven otherwise? Laryngoscope 92:27–30, 1982.PubMedCrossRefGoogle Scholar
  29. 29.
    Katz, AD. Midline dermoid tumors of the neck. Arch Surg 109:822,823, 1974.PubMedGoogle Scholar
  30. 30.
    Holt GR, Holt JE, Weaver RG. Dermoids and teratomas of the head and neck. Ear, Nose, Throat J 58:520–531, 1979.Google Scholar
  31. 31.
    Kumar AJ, Kuhajda FP, Martinez CR, Fishman EK, Jezic DV, Siegelman SS. Computed tomography of extracranial nerve sheath tumors with pathological correlation. J Comput Assist, Tomogr 7:857–865, 1983.Google Scholar
  32. 32.
    Apel RL, Asa SL, Chalvardjian A, LiVolsi VA. Intrathyroidal lymphoepithelial cysts of probable branchial origin. Hum Pathol 25:1238–1242, 1994.PubMedCrossRefGoogle Scholar
  33. 33.
    Louis DN, Vickery AL, Rosai J, Wang CA. Multiple branchial cleft-like cysts in Hashimoto's thyroiditis. Am J Surg Pathol 13:45–49, 1989.PubMedGoogle Scholar
  34. 34.
    Delabie J, De Wolf-Peeters C, Cappell L, Van Damme V. Branchial cleftlike, cysts of the thyroid. Am J Surg Pathol 14:1165–1166, 1990.PubMedCrossRefGoogle Scholar
  35. 35.
    Roediger WE, Kalk F, Spitz L, Schmaman A. Congenital thyroid cyst of ultimobranchial gland origin. J Ped Surg 12:575,576, 1977.CrossRefGoogle Scholar

Copyright information

© Humana Press Inc 1997

Authors and Affiliations

  • Catherine J. Streutker
    • 2
    Email author
  • David Murray
    • 2
  • Kalman Kovacs
    • 2
  • Hubert P. Higgins
    • 1
  1. 1.Department of MedicineMichael’s HospitalTorontoCanada
  2. 2.Department of PathologySt. Michael’s HospitalTorontoCanada

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