Abstract
A study was conducted to determine the drug resistance pattern of enterococci isolated from cases of neonatal bacteremia. A total of 41 strains of enterococci were isolated of which 35 (85.4%) wereEnterococcus faecalis and 6 (14.6%) wereEnterococcus faecium. A total of 3 (8.6%) strains ofE. faecalis and 2 (33.3%)E. faecium strains showed high level aminoglycoside resistance (HLAR). None of the enterococci tested were vancomycin resistant. Drug resistance was more common amongE. faecium strains. All clinically significant isolates of enterococci should be tested for their antibiotic sensitivity pattern including HLAR, and for treatment, antibiotics are selected based onin vitro antibiotic sensitivity test results.
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References
Eliopoulos GM. Increasing problems in the therapy of enterococcal infections.Eur J Clin Microbiol Infect Dis 1993; 12: 409–412.
Arduino RE, Murray BE. Vancomycin resistant enterococci.J Infect Dis Antimicrob Agents 1995; 12 (1): 33–40.
Patterson JE., Zervos MJ. High level gentamicin resistance in enterococcus: Microbiology, genetic basis and epidemiology.Rev Infect Dis 1990; 12 : 644–652.
Murray BE. The life and times of enterococcus.Clin Microbiol Rev 1990; 3: 46–65.
CDC. Nosocomial enterococci resistant to vancomycin. United States 1989-1993.MMWR 1993; 42: 597–599.
Campos JM, McNamara AM, Howard BJ. Specimen collection and processing. In: Howard BJ, chief ed.Clinical and Pathogenic Microbiology, second edition, St. Louis : CV. Mosby, 1995; 213–242.
Facklam RR, Sahm DF. Enterococcus. In: Murray PR, Baram EJ, Pfaller MA, Tenover FC, (eds.)The manual of Clinical Microbiology 6th ed, Washington DC, American Society for Microbiology 1995; 308–313.
National committee for Clinical Laboratory Standards: Performance standards for antimicrobial disk susceptibility tests, 4th ed, villanova, Pa, 1990, NCCLS.
Sahm DF, Torres C. High content aminoglycoside disks for determining aminogly-coside-penicillin synergy againstEnterococcus faecalis.J Clin Microbiol 1988; 26: 257–260.
Sahm DF, Torres C. Effects of medium and inoculum variation on screening of high level aminoglycoside resistance inEnterococcus faecalis.J Clin Microbiol 1988; 26: 250–256.
Swenson JA, Clark NC, Ferraro MJet al. Development of Standardized screening method for detection of vancomycin resistant enterococci.J Clin Microbiol 1994; 32: 1700–1704.
Sahm DF, Oslen L.In vitro detection enterococcal vancomycin resistance.Antimicrob Agents Chemother 1990; 34:1846–1848.
Karamfil LV, Murphy M, Josephson Aet al. A cluster of vancomycin resistant Enterococcus faecium in intensive care unit.Infect Contml Hosp Epidemiol 1992; 13:195–200.
Hall LMC. Recent advances in understanding of the epidemiology of enterococci.Rev Med Microbiol 1993; 4:192–197.
Vercanteren E, Lammens C, Pensart Net al. Survey of enterococcal susceptibility pattern in Belgium.J Clin Microbiol 1996; 34: 2572–2576.
Johnson AP, Uttley AH, Woodford N, Georage RC. Resistance to vancomycin and teicomplanins: an emerging clinical problem.Clin Microbiol Rev 1990; 3 : 280–291.
Guiot HFL, Peetermans WE, Sebens FW. Isolation of vancomycin resistant enterococci in haematologic patients.Eur J Clin Microbiol Infect Dis 1991; 10: 32–34.
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Bhat, K.G., Paul, C. & Bhat, M.G. Neonatal bacteremia due to high level aminoglycoside resistant (HLAR) enterococci. Indian J Pediatr 64, 537–539 (1997). https://doi.org/10.1007/BF02737764
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DOI: https://doi.org/10.1007/BF02737764