Skip to main content
SpringerLink
Log in

Allergic emergencies in the Physician’s office

  • Allergic Emergencies
  • Published:
Clinical Reviews in Allergy & Immunology Aims and scope Submit manuscript

Conclusion

Allergen immunotherapy may result in anaphylaxis without previous warning signs, such as a previous systemic reaction. Large local reactions are not predictive of future systemic reactions based on several published studies. Emergency medications and equipment should be kept current, and emergency preparedness by staff must be a priority. The overall rarity of severe anaphylaxis in a physician’s office may create a sense of false security. Staff should know when to call for emergency help, and it is advised that they inform the physician immediately of all immunotherapy systemic reactions. Early administration of sc epinephrine will help control and stop most but not all systemic reactions to injection therapy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Masood, D. M., Brown, J. E., Patterson, R., Greenberger, P. A., and Berkowitz, L. (1995),Ann. Allergy Asthma Immunol. 74, 311–313.

    PubMed  CAS  Google Scholar 

  2. Slater, J. E. (1994),J. Allergy Clin. Immunol. 94, 139–149.

    Article  PubMed  CAS  Google Scholar 

  3. Choy, A. C., Patterson, R., Patterson, D. R., Grammer, L. C., Greenberger, P. A., McGrath, K. G., et al. (1995),J. Allergy Clin. Immunol. 96, 893–900.

    Article  PubMed  CAS  Google Scholar 

  4. Greenberger, P. A. (1997), inIdiopathic Anaphylaxis, vol. 1, Patterson, R., ed., Oceanside Publications, Providence, RI, pp. 7–17.

    Google Scholar 

  5. Patterson, R., Schatz, M., and Horton, M. (1974),Clin. Allergy 4, 309–312.

    Google Scholar 

  6. Ruhr, A. S. and Pappano, J. E. (1992),J. Allergy Clin. Immunol. 90, 407, 408.

    Article  Google Scholar 

  7. Sussman, G. L., Tarlo, S., and Dolovich, J. (1991),JAMA 265, 2844–2877.

    Article  PubMed  CAS  Google Scholar 

  8. Muroi, N., Nishibori, M., Fujii, T., Yamagata, M., Hosoi, S., Nakaya, N., et al. (1997),N. Engl. J. Med. 337, 1275–1277.

    Article  PubMed  CAS  Google Scholar 

  9. AAAAI Board of Directors Position Statement (1994),J. Allergy Clin. Immunol. 93, 811, 812.

    Article  Google Scholar 

  10. World Health Organization Position Paper, Bousquet, J., Lockey, R. F., and Malling, H.-J., eds. (1998),Eur. J. Allergy Clin. Immunol. 44, 1–42.

    Google Scholar 

  11. Joint Task Force on Practice Parameters, Nicklas, R. A., Bernstein, I. L., Li, J. T., Lee, R. E., Spector, S. L., Dykewicz, M. S., et al., eds. (1998),J. Allergy Clin. Immunol. 101, S465–S528.

    Google Scholar 

  12. Schaefer, R. M., Schaefer, L., and Horl, W. H. (1996),Clin. Nephrol. 42, S44-S47.

    Google Scholar 

  13. American College of Allergy, Asthma, and Immunology Position Statement (1998).

  14. Lockey, R. F., Benedict, L. M., Turkeltaub, P. C., and Bukantz, S. C. (1987),J. Allergy Clin. Immunol. 79, 660–677.

    Article  PubMed  CAS  Google Scholar 

  15. Lockey, R. F. (1995),Allergy Proc. 16, 293–296.

    Article  PubMed  CAS  Google Scholar 

  16. Abramson, M. J., Puy, R. M., and Weiner, J. M. (1995),Am. J. Respir. Crit. Care Med. 151, 969–974.

    PubMed  CAS  Google Scholar 

  17. Greenberger, P. A. (1992),Immunol. Allergy Clin. North Am. 12, 1–12.

    Google Scholar 

  18. Wells, J. H. (1996),J. Allergy Clin. Immunol. 97, 1029–1032.

    Article  Google Scholar 

  19. Creticos, P. S., Reed, C. E., Norman, P. S., Khoury, J., Adkinson, N. F., Jr., Buncher, C. R., et al. (1996),N. Engl. J. Med. 334, 501–506.

    Article  PubMed  CAS  Google Scholar 

  20. Adkinson, N. F., Jr., Eggleston, P. A., Eney, D., Goldstein, E. O., Schuberth, K. C., Bacon, J. R., et al. (1997),N. Engl. J. Med. 336, 324–331.

    Article  PubMed  CAS  Google Scholar 

  21. Greenberger, P. A. (1994),Ann. Allergy 73, 378–380.

    PubMed  CAS  Google Scholar 

  22. Greenberg, M. A., Kaufman, C. R., Gonzalez, G. E., Rosenblatt, C. D., Smith, L. J., and Summers, R. J. (1986),J. Allergy Clin. Immunol. 77, 865–870.

    Article  PubMed  CAS  Google Scholar 

  23. Valysaevi, M. A., Yocum, M. W., Gosselin, V. A., and Hunt, L. W. (1997),J. Allergy Clin. Immunol. 99, S66.

    Google Scholar 

  24. Tinkleman, D. G., Cole, W. Q., and Tunno, J. (1995),J. Allergy Clin. Immunol. 95, 8–14.

    Article  Google Scholar 

  25. Portnoy, J., Bagstad, K., Kanarek, H., Pacheco, F., Hall, B., and Barnes, C. (1994),Ann. Allergy 73, 409–418.

    PubMed  CAS  Google Scholar 

  26. Hejjaoui, A., Dhivert, H., Michel, F. B., and Bousquet, J. (1990),J. Allergy Clin. Immunol. 85, 473–479.

    Article  PubMed  CAS  Google Scholar 

  27. Sharkey, P. and Portnoy, J. (1996),Ann. Allergy 76, 175–180.

    Article  CAS  Google Scholar 

  28. Tipton, W. R. and Nelson, H. S. (1982),J. Allergy Clin. Immunol. 69, 194–199.

    Article  PubMed  CAS  Google Scholar 

  29. Nielson, L., Johnsen C. R., Mosbech, H., Poulsen, L. K., and Malling, H.-J. (1996)J. Allergy Clin. Immunol. 97, 1207–1213.

    Article  Google Scholar 

  30. Grammer, L. C., Shaughnessy, M. A., Shaughnessy, J. J., and Patterson, R. (1989),J. Allergy Clin. Immunol. 83, 750–756.

    Article  PubMed  CAS  Google Scholar 

  31. Patterson, R., DeSwarte, R. D., Greenberger, P. A., Grammer, L. C., Brown, J. E., and Choy, A. C. (1994),Allergy Proc. 15, 239–264.

    Article  PubMed  CAS  Google Scholar 

  32. Doan, T. and Greenberger, P. A. (1993),Ann. Allergy 70, 439–444.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Allergy-Immunology, Department of Medicine, Northwestern University Medical School, Chicago, IL

    Paul A. Greenberger

  2. Ernest S. Bazley Asthma and Allergic Diseases Center, Northwestern University Medical School, Chicago, IL

    Paul A. Greenberger

Authors
  1. Paul A. Greenberger
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Greenberger, P.A. Allergic emergencies in the Physician’s office. Clinic Rev Allerg Immunol 17, 401–412 (1999). https://doi.org/10.1007/BF02737645

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02737645

Keywords

Search

Navigation