Skip to main content
SpringerLink
Log in

Food allergy

  • Symposium on Pediatric Allergy-II
  • Published:
The Indian Journal of Pediatrics Aims and scope Submit manuscript

Abstract

Allergic disease is a major contributor to illnesses and mortality worldwide. Food hypersensitivity is often the first phenomenon in the allergic march that includes gastroenteropathy, eczema, asthma and hay fever. Recent evidence indicates that prevention of food hypersensitivity in early life is associated with reduction in the incidence of eczema and asthma in later childhood. Strategies for prevention include exclusive breast feeding, restriction of mother’s diet during lactation, hydrolyzed formula, delayed introduction of allergenic solid foods and reduced exposure to house dust mites and tobacco smoke. This is a highly cost-beneficial and cost-effective approach.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Taylor B, Wadsworth J. Wadsworth M, Peckham C. Changes in the prevalence of eczema since the 1939-45 war.Lancet 1984; 2: 1255–1277.

    Article  PubMed  CAS  Google Scholar 

  2. Burney PGJ, Chinn S, Rona R. Has the prevalence of asthma increased in children?Br Med J 1990; 300: 1306–1310.

    CAS  Google Scholar 

  3. Dean T. Prevalenceof allergic disorders in early infancy.Pediatr Allergy Immunol 1997; 10: 27.

    Google Scholar 

  4. Epidemiology. Prevalence of allergic diseases. In De Weck A, Proost H, eds.European Allerg White Paper. Allergic Diseases as a Public Health Problem. Brussels: UCB Institute of Health, 1997. P. 14–35.

  5. Strachan D, Sibbald B, Weiland S, Ait-Khaned N, Anabwani G, Anderson HR. Worldwide variations in prevalence of symptoms of allergic rhinoconjuctivitis in children: the International Study of Asthma and Allergies in Childhood (ISAAC).Pediatr Allerg Immunol 1997; 8: 161–167.

    Article  CAS  Google Scholar 

  6. Tariq SM, Matthews, SM, Hakim EA, Steens M, Arshad SH, Hide DW. The prevalence of risk factors for atopy in early childhood: a whole population birth cohort study.J Allerg Clin Immunol 1998; 101: 587–593.

    Article  CAS  Google Scholar 

  7. Aberg N, Hesselmar B, Aberg B, Eriksson B. Increase in asthma, allergic rhinitis and eczema in Swedish school children between 1979-1991.Clin Exp Allerg 1995; 25: 815–819.

    Article  CAS  Google Scholar 

  8. Bousquet J, Burney P. Evidence of an increase in atopic disease and possible causes.Clin Exp Allerg 1993; 23: 484–492.

    Article  CAS  Google Scholar 

  9. Burkholter D, Schiffer P. The epidemiology of atopic diseases in Europe: a review.Allerg Clin Immunol News 1995; 7: 113–125.

    Google Scholar 

  10. Chandra RK. Food allergy. 1992 and beyond.Nutr Res 1992; 12: 93–99.

    Article  Google Scholar 

  11. Chandra RK. Five year follow-up high risk infants with family history of allergy who were exclusively breast fed or fed partial hydrolysate, soy and conventional cow’s milk formulae.J Ped Gastroent Nutr 1997; 24: 380–388.

    Article  CAS  Google Scholar 

  12. Socio-economic costs of allergic diseases. In : De Weck A, Proost Ph, eds.European Allerg White Paper: allergic diseases as a Public Health Problem Brussels : UCB Institute of Health, 1997.p. 98-112.

  13. Croner S, Kjellman N-IM. Development of atopic disease in relation to family history and cord blood IgE levels. Eleven year follow-up in 1654 children.Pediatr Allerg Immunol 1990; 1: 14–20.

    Article  Google Scholar 

  14. Zeiger RS, Heller S, Mellon MH, Forsythe AB, O’Connor RD, Hamburger RNet. al. Effect of combined maternal and infant food allergen avoidance on development of atopy in early infancy.J Allerg 1989; 84: 72–89.

    CAS  Google Scholar 

  15. Arshad SH, Matthews S, Grant C, Hide DW. Effect of allergen avoidance on development of allergic disorders in infancy.Lancet 1992; 339: 1493–1497.

    Article  PubMed  CAS  Google Scholar 

  16. Chandra RK, Singh GK, Shridhara B. Effect of feeding whey hydrolysate, soy and conventional cow milk formulas on incidence of atopic disease in high risk infants.Ann Allerg 1989; 63: 102–106.

    PubMed  CAS  Google Scholar 

  17. Chandra RK, Hamed A. Cumulative incidence of atopic disorders in high risk infants fed whey hydrolysate, soy and conventional cow milk formulas.Ann Allerg 1991; 67: 129–132.

    PubMed  CAS  Google Scholar 

  18. Vandenplas Y, Hauser B, Van den Borre C, Sacre L, Dab J. Effect of a whey hydrolysate prophylaxis of atopic disease.Ann Allerg 1992; 68: 419–423.

    PubMed  CAS  Google Scholar 

  19. Wilhems R, Duichateau J, Magrez P, Denis R, Casimir G. Influence of hypoallergenic milk formula on the incidence of early allergic manifestations in infants predisposed to atopic diseases.Ann Allerg 1993; 71: 147–150.

    Google Scholar 

  20. Marini A, Agosti M, Motta G, Lusardia C. Dietary prophylaxis in infants with high risk of atopic diseases.Riv Ital Pediatr 1990; 16: 391–398.

    Google Scholar 

  21. Saarinen U, Kajosaari M. Breastfeeding as prophylaxis against atopic disease: prospective follow-up study until 17 years old.Lancet 1995; 346: 1065–1069.

    Article  PubMed  CAS  Google Scholar 

  22. Chandra RK, Puri S, Hamed A. Influence of maternal diet during lactation and use of formula feeds on development of atopic eczema in high risk infants.Br Med J 1989; 299: 228–230.

    CAS  Google Scholar 

  23. Hattevig G, Kjellman B, Sigurs Net al. The effect of maternal avoidance of eggs, cow’s milk and fish during lactation on allergic manifestations in infants.Clin Allerg 1968; 19: 27–32.

    Article  Google Scholar 

  24. Bahna SL. Breast milk and special formulas in prevention of milk allergy. In Mestecky J, Blair B, Ogra PL, eds.Immunology of Milk and Neonate. New York, Plenum, 1991: 445–448.

    Google Scholar 

  25. Gruskay FL. Comparison of breast, cow and soy feedings in the prevention of onset of allergic disease.Clin Pediatr 1982; 21: 486–491.

    CAS  Google Scholar 

  26. Halken S, Hansen LG, Skamstrup K, Jacobsen HP, Estmann A, Engberg Aet al. Comparison of a partially hydrolysed infant formula with two extensively hydrolysed formulas for allergy prevention: a prospective randomised study.Ped All Immun 2000; 11: 149–161.

    Article  CAS  Google Scholar 

  27. Halken S, Host A, Hansen LG, Osterballe O. Effect of an allergy prevention programme on incidence of atopic symptoms in infancy.Allerg 1992; 47: 543–553.

    Google Scholar 

  28. Marini A, Agosti M, Motta G, Mosca F. Effects of a dietary and environmental prevention programme on the incidence of allergic symptoms in high atopic risk infants: three year’s follow up.Acta Pediatr Scand 1996; 85 (Suppl. 414): 1–22.

    Google Scholar 

  29. Vandenplas Y, Hauser B, Van den Borre C, Sacre L, Dab I, Deneyer M. Effect of whey hydrolysate prophylaxis on atopic disease.Ann Allerg1992; 68: 419–423.

    PubMed  CAS  Google Scholar 

  30. Zeiger RS, Heller S. The development and prediction of atopy in high risk children: follow-up at age seven years in a prospective randomised study of combined maternal and infant food allergen avoidance.J Allerg Clin Immunol 1995; 95: 1179–1190.

    Article  CAS  Google Scholar 

  31. Baumgartner M, Brown CA, Exl BM, Secretin M-C, Van’t Hof M, Haschke F. Controlled trials investigating the use of one partially hydrolyzed whey formula for dietary prevention of atopic manifestations until 60 months of age: an overview using meta-analytical techniques.Nutr Res 1998; 18:1425–1442.

    Article  CAS  Google Scholar 

  32. Porch MC, Shahane AD, Leiva LE, Elston RC, Sorensen RU. Influence of breast milk, soy or two hydrolyzed formulae on the development of allergic manifestations in infants at risk.Nutr Res 1998; 18: 1413–1424.

    Article  CAS  Google Scholar 

  33. Chandra RK, Gill B, Kumari S. Food allergy.Ann Allerg 1993; 71: 495–502.

    PubMed  CAS  Google Scholar 

  34. Subcommittee on Nutrition and Allergic Disease. Infant formulas and allergic disease. Elks Village, Illinois:American Academy of Pediatrics, 1990.

  35. Kleinman RE, Bahna S, Powell GF, Sampson HA. Use of infant formulas in infants with cow milk allergy. A review and recommendations.Pediatr Allerg Immunol 1991; 2: 146–155.

    Article  Google Scholar 

  36. Businco L, Bruno G, Giampietro PG, Cantani A. Allergencity and nutritional adquacy of soy protein formulas.J Pediatr 1992; 121: 21–28.

    Google Scholar 

  37. Collin-Willaims C. Current status of hydrolysates in the prevention of allergy. In Chandra RK, ed.Nutrition and Immunology. St. John’s Newfoundland ARTS Biomedical, 1992; 379-390.

  38. Report of the Scientific Committee for Food on Infant Formulae claimed to be Hypoallergenic or Hypoantigenic. Brussels, 9.12.1991. Ec Reports Food Science and Techniques, 1991.

  39. AAP Committee on Nutrition (Baker SS, Coachran WJ, Greer FR, Heyman MB, Jacobson MS, Jaksic T, Krebs NF). Hypoallergenic Infant Formulas.Pediatrics 2000; 106: 346–349.

    Article  Google Scholar 

  40. Kjellman N-IM, Nilsson L. Is allergy revention realistic and beneficial?Pediatr Allerg Immunol 1999: 10 (Suppl 12): 11–17.

    CAS  Google Scholar 

  41. Host A, Koletzko B, Dreborg S, Muraro A, Wahn U, Aggett P.et al. Joint statement of ESPACI and ESPGHAN. Dietary products used in infants for treatment and prevention of food allergy.Arch Dis Child 1999; 81: 80–84.

    PubMed  CAS  Google Scholar 

  42. Oldaeus G, Anjou K, Bjorksten B, Moran JR, Kjellman N-IM. Extensively and partially hydrolysed infant formulae for allergy prophylaxis.Arch Dis Child 1997; 77: 4–10.

    Article  PubMed  CAS  Google Scholar 

  43. Chandra RK, Gill B, Kumari S. Food allergy and atopic disease.Clin Rev Allerg Immunol 1995; 13: 293–314.

    CAS  Google Scholar 

  44. Kerner JA. Use of infant formulas in preventing or postponing atopic manifestations.J Pediatr Gastroenterol Nutr 1997; 24: 442–446.

    Article  PubMed  Google Scholar 

  45. Exl BM. A review of recent developments in the use of moderately hydrolyzed whey formulae in infant nutrition.Nutr Res 2001; 21: 355–380.

    Article  CAS  Google Scholar 

  46. Chandra RK. Breast feeding, hydrolysate formulas and delayed introduction of selected foods in the prevention of food hypersensitivity and allergic disease.Nutr Res 2002; 22.

Download references

Author information

Authors and Affiliations

  1. Memorial University of Newfoundland, St. John’s, Newfoundland, Canada

    R. K. Chandra

Authors
  1. R. K. Chandra
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to R. K. Chandra.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chandra, R.K. Food allergy. Indian J Pediatr 69, 251–255 (2002). https://doi.org/10.1007/BF02734235

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02734235

Key words

Search

Navigation