Abstract
Recent research has found that people with Irritable Bowel Syndrome (IBS) and those with Inflammatory Bowel Disease (IBD) show a relative deficit in verbal IQ, compared to their own performance IQ, and the IQ of a healthy comparison group. It has been suggested that the elevated prevalence of left-handedness shown in previous studies investigating people with IBD is due to compromised left-hemisphere development. This may be associated with a decrement in certain cognitive functions such as verbal IQ. A shift in brain dominance from left to right has been found in many atopic and immunological diseases as well as in autonomic dysfunctions. It was uncertain whether this would apply to people with IBS, a functional disorder in which the cause or causes remain unclear. Therefore, the aim of this preliminary study was to investigate whether people with IBS have an increased prevalence of left-handedness. It was found that there was an association between IBS and left-handedness, showing that further research on this association both in IBS and other functional disorders (as well as on the similarities between IBS and IBD) is warranted.
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Andreou, G., Krommydas, G., Gourgoulianis, K.I., Karapetsas, A., & Molyvdas, P.A. (2002). Handedness, asthma and allergic disorders: Is there an association?Psychology, Health & Medicine 7(1), 53–59.
Attree, E.A., Dancey, C.P., Keeling, D., & Wilson, C. (2003). Cognitive function in people with chronic illness: Inflammatory bowel disease and irritable bowel syndrome.Applied Neuropsychology 10, 96–104.
Bryden, M.P., McManus, I.C. & Steenhuis, R.E. (1991). Handedness is not related to self-reported disease incidence.Cortex, 27, 6 5–611.
Bryden, M.P., McManus, I.C., & Bulman-Fleming, M.B. (1994). Evaluating the empirical support for the Geschwind-Behan-Galaburda model of cerebral lateralization.Brain and Cognition, 26, 103–167.
Chadwick, V.S., Chen, W., Shu, D., Paulus, B., Bethwaite, P., Tie, A., & Wilson, I. (2002). Activation of the mucosal immune system in irritable bowel syndrome.Gastroenterology, 122, 1778–1783.
Cornell, E. & McManus, I.C., (1992). Differential survey response rates in right and left-handers.British Journal of Psychology, 83, 39–43.
De Giorgio, R., Guerrini, S., Barbara, G., Stanghellini, V., De Ponti, F., Corinaldesi, R., Moses, P.L., Sharkey, K.A., & Mawe, G.M. (2004). Inflammatory neuropathies of the enteric nervous system.Gastroenterology, 126, 1872–1883.
Gilbert, A.N. & Wysocki, C.J. (1992). Hand preference and age in the United States.Neuropsychologia, 30, 601–608.
Holtmann, G., Siffert, W., Haag, S., Mueller, N., Langkafel, M., Senf, W., Zotz, R., & Talley, N.J. (2004). G-protein beta 3 subunit 825 CC genotype is associated with unexplained (functional) dyspepsia.Gastroenterology, 126(4), 971–979.
Kaynar, H. & Dane, S. (2003). Prevalence of left-handedness among patients with different respiratory diseases.International Journal of Neuroscience, 113(10), 1371–1377.
Kennedy, T.M. & Jones, R.H. (2000) Epidemiology of cholecystectomy and Irritable Bowel Syndrome in a UK population.British Journal of Surgery, 87(12), 1658–1663.
Lane, R.D. & Jennings, J.R. (1995). Hemispheric asymmetry, autonomic asymmetry, and the problem of sudden cardiac death. In: Davidson, R.J. & Hugdahl, K. (eds)Brain Asymmetry. Cambridge, M.A.: The MIT Press.
McManus, I.C. (2002).Right hand, left hand: The origins of asymmetry in brains, bodies, atoms and cultures. London, Weidenfeld & Nicholson, p. 151.
Morris, D.L., Montgomery, S.M., Galloway, M.L., Pounder, R.E., & Wakefield, A.J. (2001). Inflammatory bowel disease and laterality: Is left handedness a risk?Gut, 49, 199–202.
O’Sullivan, M., Clayton, N., Breslin, N.P., Harman, I., Bountra, C., Mclaren, A., & O’Morain, C.A. (2000). Increased mast cells in the irritable bowel syndrome.Neurogastroenterol. Mot. 12, 449–457.
Persson, G. & Ahlbom, A. (1987). Relative risk is a relevant measure of association of left handedness with Inflammatory Bowel Disease.Neuropsychologia, 26(5), 737–738.
Quigley, E.M.M. (2004). Functional Gastrointestinal Disease: Has the genomic era arrived?Gastroenterology, 126, 1193–1195.
Phillips, S.F. (1996).The Irritable Bowel Syndrome. Paper presented at Therapeutic Challenges of Irritable Bowel Syndrome Conference, 19–20 February, London.
Saito, Y.K., Schoenfeld, P., & Locke, III, G.R. (2002). The epidemiology of Irritable Bowel Syndrome in North America: A systematic review.The American Journal of Gastroenterology, 97(8), 1910–1915.
Searleman, A. & Fugagli, A.K. (1987). Suspected autoimmune disorders and left-handedness: Evidence from individuals with diabetes, Crohn’s Disease and Ulcerative Colitis.Neuropsychologia, 25(2), 367–374.
Spiller, R.C. (2003). Postinfectious irritable bowel syndrome.Gastroenterology, 124, 1662–1671.
Talley, N.J., Boyce, P.M., & Jones N. (1997). Predictors of health care seeking for irritable bowel syndrome: A population based study.Gut, 41, 394–398.
Tonnessen, F.E., Lokken, A., Hoien, T., & Lundberg, I. (1993). Dyslexia, left-handedness, and immune disorders.Archives of Neurology, 50, 411–416.
Waldie, K.E., Hausmann, M., Milne, B.J., & Poulton, R. (2002). Migraine and cognitive function: A life-course study.Neurology, 59, 904–908.
Warrington, E.K., James, M., & Maciejewski, C. (1986). The WAIS as a lateralising and localising diagnostic instrument.Neuropsychologia, 24, 223–39.
Wittling, W. (1995). Brain asymmetry in the control of autonomic-physiologic activity. In: Davidson, R.J. & Hugdahl, K. (eds)Brain Asymmetry. Cambridge, M.A.: The MIT Press.
Wechsler D. (1992).WISC III (UK) manual. Harcourt Brace & Company.
The Psychological Corporation (1999).Wechsler Abbreviated Scale of Intelligence, San Antonio, TX.
Whelan, W. (1998). Effects of sex and lesion locus on measures of intelligence.Journal of Consulting and Clinical Psychology, 56, 633–635.
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Dancey, C.P., Attree, E.A., Bàrdos, G. et al. Is there a link between irritable bowel syndrome and left-handedness?: An exploratory study. Integr. psych. behav. 40, 55–59 (2005). https://doi.org/10.1007/BF02734189
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DOI: https://doi.org/10.1007/BF02734189