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Neuroplasticity in children

  • Symposium on Developmental and Behavioral Disorders-I
  • Published:
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Abstract

Research in the field of neurosciences and genetics has given us great insight into the understanding of learning and behavior and changes in the brain in resonse to experience. It is seen that brain is dynamically changing throughout life and is capable of tearing at any time. Critical periods of neuroplasticity for various streams of development are also beter understood. Technological advances in non invasive imaging techniques and advances in moleculoar genetics have helped us understand the basis of many developmental disorders which may help in planning effective intervention strategies.

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References

  1. Sarnat HB, Menkes JH. Neuroembrylogy, Genetic Programming and Malformations of the Nervous system. In Menkes JH, Sarnat HB, ed.Child Neurology. Lippincott Williams and Wilkins, 2000.

  2. Johnston MV. Nishimura A, Harum K, Pekar J, Blue ME. Sculpting the developing brain.Adv Pediatr 2001; 48:1–38.

    PubMed  CAS  Google Scholar 

  3. Boatman D, Freeman J, Vining Eet al. Language recovery after left hemispherectomy in children with late-onset seizures,Ann Neurol 1999; 46:579–586.

    CAS  Google Scholar 

  4. Raff MC, Barres BA, Burne JF, Coles HS, Ishizaki Y, Jacobson MD, Programmed cell death and the control of cell survival; lessons from the nervous system.Science 1993; 262:695–700.

    Article  PubMed  CAS  Google Scholar 

  5. Buonomano DV. Cortical plasticity from synapses to maps.Annu Rev Neurosci 1998; 21:149–183.

    Article  PubMed  CAS  Google Scholar 

  6. Malenka RC, Nicoll RA. Long-term potentiation-a decade of progress?Science 1999; 285:1870–1874.

    Article  PubMed  CAS  Google Scholar 

  7. Bliss TVP, Collingridge GL. A synaptic model of memory: Long term potentiation in the hippocampus.Nature 1993; 361: 31–39

    Article  PubMed  CAS  Google Scholar 

  8. Johnston MV. Clinical disorders of brain plasticity.Brain & Development 2004; 26:73–80.

    Article  Google Scholar 

  9. Chugani HT. Metabolic imaging: a window on brain development and plasticity.Neuroscientist 1999; 5:29–40.

    Article  Google Scholar 

  10. Schinder AF, Poo M-M. The neurotrophin hypothesis for synaptic plasticity.Trends Neurosci 2000; 23:639–645.

    Article  PubMed  CAS  Google Scholar 

  11. Vaegan TD. Critical period for deprivation for amblyopia in children.Trans Ophthalmol Soc UK 1979; 99:432–439.

    PubMed  CAS  Google Scholar 

  12. Sharma A, Dorman A, Dorman MF, Sphar AJ A sensitive period for the development of the central auditory system in children with cochlear implants; implications for age of implantation.Ear Hear 2002; 23: 532–539.

    Article  PubMed  Google Scholar 

  13. Harum KH, Alemi L, Johnston MV. Cognitive impairment in Coffin-Lowry syndrome correlates with reduced RSK2 activation.Neurology 2001; 56:207–214.

    PubMed  CAS  Google Scholar 

  14. Johnston MV, Jeon OH, Pevsner J, Blue ME, Naidu S. Neuro biology of Rett syndrome: a genetic disorder of synapse development.Brain Dev 2001; 23: S206–213.

    Article  PubMed  Google Scholar 

  15. Todd PK, Malter JS, Fragile X. Mental retardation protein in plasticity and disease.J Neurosci Res 2002; 70:623–630.

    Article  PubMed  CAS  Google Scholar 

  16. Johnston MV, Alem L, Harum KH. Learning, memory and transcription factors.Pediatr Res 2003:369–374.

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Authors and Affiliations

  1. Department of Developmental Pediatrics, Bangalore Children Hospital, Chitrapur Bhavan, 15th Cross, 8th Main, Malleswaram, 560046, Bangalore, India

    Nandini Mundkur

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  1. Nandini Mundkur
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Correspondence to Nandini Mundkur.

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Mundkur, N. Neuroplasticity in children. Indian J Pediatr 72, 855–857 (2005). https://doi.org/10.1007/BF02731115

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  • DOI: https://doi.org/10.1007/BF02731115

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