Abstract
Lymphoma accounts for some 10% of childhood malignancy. Hodgkins disease is slightly less common than Non Hodgkins lymphoma, of which lymphoblastic, Burkitts and large cell anaplastic are the common subtypes. Accurate subtyping and staging are critical to ensure correct therapy is initiated. With current therapeutic strategies, almost all cases of Hodgkins and in excess of 70% of Non Hodgkins lymphomas can be cured.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Harris NL, Jaffe ES, Stein H,et al. A revised European-American classification of lymphoid neoplasms: A proposal from the International Lymphoma Study Group.Blood 1994; 84 (5): 1045–1047.
Armstrong AA, Shield L, Gallagher A, Jarrett RF. Lack of invovtement of known oncogenic DNA viruses in Epslein-Barr virus-negative Hodgkin’s disease.Brit J Cane 1998; 77 (7): 1045–1047.
Kanzler H; Kuppers R, Hansmann M-L, Rajewsky K. Hodgkin and ReedStemberg cells’in Hodgkin’s disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal centre B cells.J Exp Med 1996; 184 (4): 1495–1505.
Shankar AG, Shley S, Radford M. Barrett A, Wright D, PirVkerton CR. Does histology influence outcome in childhood Hodgkin’s disease? Results from the United Kingdom Children’s Cancer Study Group,J Clin Onc 1997; 15 (7): 2622–2630.
Kaplan HS, Rosenberg SA. The treatment of Hodgkin’s Disease.Med Clin North Am 1966; 50:1591–1610.
Windebank KP, Gilchrist GS. Hodgkin’s Disease.Pediatric Annds 1988; 17 (3): 204–223.
Carbone PP, Kaplan HS, Husshof K, Smithers DW, Tubiana M. Report of the committee on Hodgkin’s disease staging classification.Can Res 1971; 31 (11): 1860–1861.
DeVita VT, Serpick A, Carbone PP. Combination chemotherapy in the treatment of advanced Hodgkin’s Disease.Ann Int Med 1970; 73: 881–895.
McElwain TJ, Toy J, Smith E, Peckham MJ, Austin DE. A combination of chlorambucil, vinblastine, procarbazine and prednisolone for treatment of Hodgkin’;s disease.Br J Cane 1977; 36 (2): 276–280.
Bonadonna G, Zucali R. Monfardini S, DeLena M, Uslenghi C. Combination chemotherapy of Hodgkin’s disease with adriamycin, bleomycin, vinblastine, and imidazole carboxamide versus MOPP.Cancer 1975; 36: 252–259.
Barrett A, Crenn’an E, Barnes J, Martin J, Radford M, Treatment of clinical stage I Hodgkin’s disease by local radiation therapy alone.Cancer 1990; 66 (4): 670–674.
Vlachaki MT, Hagemeister FB, Fuller LM,et al. Long-term outcome of treatment for Ann Arbor Stage I Hodgkin’s disease: prognostic factors for survival and freedom from progression.Int. J Radiat Oncol Biol Phys 1997; 38 (3): 593–599.
Nathwani BW, Kim H, Rappaport H. Malignant lymphoma, lymphoblastic. Cancer 1976; 38:964–983.
Lukes RJ, Collins RD. New approaches to the classification of the lymphomata.Br J Cancer 1975; 31 (suppl II): 1–28.
Azizkhah RG, Dudgeon DL, Buck JR,et al. Life-threatening airway obstruction as a complication to, the management of mediastinal masses in children.J Fed Srug 1985; 20 (6): 816–822.
Murphy SB. Classification, staging and end result of treatment of childhood nonHodgkin’s lymphomas: dissimilarities form lymphomas in adults.Seminars in Oncology 1980; 7 (3): 332–339.
Anderson JR, Wilson JF, Jenkin DT,et al. Childhood non-Hodgkin’s lymphoma. The resutls of a randomized therapeutic trial comparing a 4-drug regimen (COMP) with a 10-rug regimen (LSA2-L2).N Engl J Med 1983; 308 (10): 559–565.
Eden OB, Hann I, Imeson J, Cotteril S, Gerrard M, Pinkerton CR. Treatment of Advanced stage T cell lymphoblastic lymphoma: Results of the United Kingdom Children’s Cancer Study Group (UKCCSG) protocol 8503.Br J Haem 1992; 82 (2): 310–316.
Windebank KT, Barrett AM, Leese D, Philpott C, Mayo G, Imeson J. Complications of central venous catheters in UKCCSG/PONF Centres 2nd Annual Spring Meeting of RCPCH. York 1998.
Patte C, Michon J, Frappaz D,et al. Therapy of Burkitt and other B-cell acute lymphoblastic leukaemia and lymphoma: Experience with the LMB protocols of the SFOP (French Paediatric Oncology Society) in children and adults.Bailliers Clinical Haematology; 1994; 7 (2): 339–348.