Abstract
The validity of the Verbal Autopsy (VA) in death due to acute respiratory infection (ARI), Was tested in 36 children who died by any acute infectious disease as stated by the necropsy diagnosis, at two public hospitals in Mexico City; the illness started at home. Clinical data obtained through VA were compared with diagnoses of necropsies, which were considered as “gold standard”. The presence of dyspnoea for more than one day showed sensitivity of 0.69 and Specificity of 0.74, while history of coughing showed a sensitivity of 0.61 and a specificity of 0.73. Combination of both clinical data improved specificity (0.83), but decreased sensitivity (0.54). Additional sources of diagnosis (a panel of assessors, the clinical record and the death certificate), also showed good sensitivity (0.69–0.77) and specificity (0.74–7.8). Focus on history of dyspnea and/or cough in children with an infectious syndrome should be emphasized, as a useful epidemiologic tool to determine children’s mortality due to ARI in areas where diagnosis resources are constrained.
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References
Gray RH, Smith G, Barss P.The use of verbal autopsy methods to determine selected causes of death in children. The Johns Hopkins University. School of Hygiene and Public Health. Institute for International Programmes’. Baltimore, Occasional Paper 1990, No. 10, pp. 7–11.
Mtango EDE, Neuvians D. Acute respiratory infections in children under five years. Control project in Bagamoyo District, Tanzania.Trans R Soc Trop Med Hyg 1986; 80:851–858.
Gutierrez G, Reyes H, Martinez H, Tome P, Guiscafre H. Study of the diseasehealth seeking-Death process: Another use of the verbal autopsy.Int J Epidemiol 1994; 23:427–428.
Weekly Epidemiological Record.WHO 1993; 68:353–360.
Kalter HD, Gray RH, Black RE, Gultiano SA. Validation of postmortem interviews to ascertain selected causes of death in children.In J Epidemiol 1990; 19: 380–386.
Quigley MA, Armstrong JRM, Snow RW, Algorithms for verbal autopsies: A validation study in Kenyan children.Bull WHO 1996; 74 :147–154.
Tome P, Reyes H, Guiscafre H, Martinez H, Rodriguez L, Gutierrez G. Sobrediagnóstico de infección respiratoria y diarrea aguda en muertes de niños en Tlaxcala, Mexico. Analisis comparativo entre certificados de defuncion y “autopsias verbales:Bol Med Hosp Infant (Mex) 1994; 51: 159–166.
Tome P, Reyes H, Rodriguez L, Guiscafre H, Gutierrez G. Muerte por diarrea aguda en ninos: un estudio de factores pronosticos.Salud Publiai Mex 1996; 38 :227–235.
Snow RW, Armstrong RM, Forster D,et al. Childhood deaths in Africa ; uses and limitations of verbal autopsies.Lancet 1992; 340:351–355
Pacque-Maragolis S, Pacque M, Pukuly Z, Boateng J, Taylor HR-Application of the verbal autopsy during 3 clinical trial.Soc, Sci Med 1990; 31: 585–591.
Gray R. Verbal autopsy,Using interviews to determine muses of death in children. he Johns Hopkins University, School of Hygiene and Publie HealthInstitute for international Programmes. Baltimore, Occasional Paper No, 1991,14, pp. 20–23.
World Health Organization. Technical bases for the WHO recommendations pn the management of pneumonia in children at first level health facilities. Geneva 1991;WHO/AKI/91.20.
Todd JE, O’Dempsey TJD, Greenwood BM. The limitations of verbal autopsy in a malaria-endemic region.Ann Trop Paediatr 1994; 14: 31–36.
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Rodriguez, L., Reyes, H., Tome, P. et al. Validation of the verbal autopsy method to ascertain acute respiratory infection as cause of death. Indian J Pediatr 65, 579–584 (1998). https://doi.org/10.1007/BF02730899
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DOI: https://doi.org/10.1007/BF02730899