Skip to main content
SpringerLink
Log in

Sirenomelia with radial dysplasia

  • Clinical Brief
  • Published:
The Indian Journal of Pediatrics Aims and scope Submit manuscript

Abstract

Sirenomelia is a rare anomaly usually associated with other multiple malformations. In this communication the authors report a case of sirenomelia associated with multiple malformations, which include radial hypoplasia also. Though several theories have been proposed regarding the etiology of multiple malformation syndromes in the past, the recent theory of primary developmental defect during blastogenesis holds good in this case.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. McCoy MC, Chescheir NC, Kuller JA, Altman GC, Flannagan MC. A fetus with sirenomelia, omphalocele and meningomyelocele, but normal kidneys.Teratology 1994; 50: 168–171.

    Article  PubMed  CAS  Google Scholar 

  2. Kallen B, Castilla EE, Lancaster PA, Mutchinick O, Knudsen LB, Martinez-Frias ML, Mastroiacovo P, Robert E. The Cyclops and the mermaid: an epidemiological study of two types of rare malformation.J Med Genet 1992; 29: 30–35.

    Article  PubMed  CAS  Google Scholar 

  3. Buyse ML. Birth Defects Encyclopedia. Dover, center for birth defects information services, Inc. 1990; 1541–1542.

  4. Kulkarni ML, Sureshkumar C, Sindhur PS. Sirenomelia with spina bifida.Indian Pediatr 1994; 31: 51–55.

    PubMed  CAS  Google Scholar 

  5. Perez Aytes A, Montero L, Gomez J, Paya. A single aberrant umbilical artery in a fetus with severe caudal defects: sirenomelia or caudal dysgenesis.Am J Med Genet 1997; 69: 409–412.

    Article  Google Scholar 

  6. Stevenson RE, Jones KL, Phelan MC, Barr M, Clericuzio C, Harley RA, Benirschke K. Vascular steal: the pathogenetic mechanism producing sirenomelia and associated defects of the viscera and soft tissues.Pediatrics 1986; 78: 451–457.

    PubMed  CAS  Google Scholar 

  7. Egan JF, Petrovsky BM, Vintzileos AM, Rodis JF, Campbel WM. Combined pentology of Cantrell and sirenomelia: a case report with speculation about a common etiology.Am J Perinatol 1993; 10: 327–329.

    PubMed  CAS  Google Scholar 

  8. Adra A, Cordero D, Mejides A, Yasin S, Salman F, O’Sullivan MJ. Caudal regression syndrome: etiopathogenesis, prenatal diagnosis and perinatal management.Obstet Gynecol Surv 1994; 49: 508–516.

    Article  PubMed  CAS  Google Scholar 

  9. Martinez-Frias ML, Frias JL. Clinical and epidemiological study of blastogenetic anomalies and their relationship to different MCA patterns.Am J Med Genet 1997; 70: 11–15.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pediatrics, JJM Medical College, Davangere, 577004, Karnataka, India

    M. L. Kulkarni (Professor and H.O.D.), K. M. Abdul Manaf, D. G. Prasannakumar & Preethi M. Kulkarni

Authors
  1. M. L. Kulkarni
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. K. M. Abdul Manaf
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. D. G. Prasannakumar
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Preethi M. Kulkarni
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to M. L. Kulkarni.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kulkarni, M.L., Abdul Manaf, K.M., Prasannakumar, D.G. et al. Sirenomelia with radial dysplasia. Indian J Pediatr 71, 447–449 (2004). https://doi.org/10.1007/BF02725639

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02725639

Key words

Search

Navigation