The Indian Journal of Pediatrics

, Volume 71, Issue 5, pp 437–440 | Cite as

Sengers disease: A rare association of hypertrophic cardiomyopathy and congenital cataracts

  • M. AtiqEmail author
  • S. Iqbal
  • S. Ibrahim
Clinical Brief


Hypertrophic cardiomyopathy is an uncommon childhood cardiac disease and can be primary or secondary. Several systemic diseases are known to be associated with this entity. Senger’s disease is a mitochondrial disorder causing congenital cataracts lactic acidosis and skeletal and cardiac myopathy. Diagnosis should be kept in mind when routine neonatal eye screening reveals absent red reflex. The authors report a case of Sengers disease and discuss the underlying pathogenetic mechanisms.

Key words

Hypertrophic cardiomypopathy Cataracts Sengers disease 


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Copyright information

© Dr. K C Chaudhuri Foundation 2004

Authors and Affiliations

  1. 1.Department of PediatricsThe Aga Khan University HospitalKarachiPakistan

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