Abstract
Secondary sex characteristics were evaluated in thalassemic children (41, boys and 30 girls), who were on regular transfusion therapy and were above 11 years of age. The results of this study indicate that the development of secondary sex characteristics in thalassemic children is markedly delayed as compared to their non-thalassemic siblings and to the expected development criteria. Delay in development of secondary sex characteristics appears to be secondary to chronic hypoxia and iron overload.
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George, A., Bhaduri, A. & Choudhry, V.P. Development of secondary sex characteristics in multitransfused thalassemic children. Indian J Pediatr 64, 855–859 (1997). https://doi.org/10.1007/BF02725511
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DOI: https://doi.org/10.1007/BF02725511