Skip to main content
SpringerLink
Log in

Urinary calcium to creatinin ratio in children

  • Clinical Brief
  • Published:
The Indian Journal of Pediatrics Aims and scope Submit manuscript

Abstract

Due to difficulty of 24hr urine collection in children for detection of hypercalciura, random urine calcium to creatinin ratio (U Ca/Cr) has been used for screening hypercalciuria. The purpose of this study was to determine normal U Ca/Cr ratio in primary school age children in North of Iran. This study was performed on 590 healthy school-age children, aged between 7–11 years. Early morning random urine samples from all children were analyzed for calcium and creatinine. Mean value and 95th percentile for U Ca/Cr ratio were 0.155 ±0.095 and 0.36, respectively. A negative correlation observed between age and U Ca/Cr ratio was R=-0.101, P=0.014. With regard to variations in U Ca/Cr ratio among different studies, it is recommended to determine this ratio in every geographic area.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Spitzer A, Chensy RW. Role of the kidney in mineral metabolism. In Edelman C Jr, Bernstein J, Meadow SRet al, eds.Pediatrics Kidney Disease. 2nd edn. Little Brown and Company, 1992; 147–184

  2. Moxey-Mims MM, Stapleton FB. Hypercalciuria and nephrocalcinosis in children.Curr Opin Pediatr 1993; 5: 186–190.

    Article  PubMed  CAS  Google Scholar 

  3. Stapleton FB. Idiopatic hypercalciuria: association with isolated hamaturia and risk for urolithiasis in children. The Southwest Pediatric Nephrology Study Group.Kidney Int 1990; 37: 807–811.

    Article  PubMed  CAS  Google Scholar 

  4. Sargent JD, Stukel TA, Kresel J. Normal values for random urinary calcium to creatinin ratios in infancy.J Pediatr 1993; 123: 393–397.

    Article  PubMed  CAS  Google Scholar 

  5. Matos V, Van Melle G, Boulat Oet al. Urinary phosphate/ creatinin, calcium /creatinin and magnesium/creatinin ratios in a healthy pediatric population.J Pediatr 1997; 131: 252–257.

    Article  PubMed  CAS  Google Scholar 

  6. Esbjorner E, Jones IL. Urinary calcium excretion in Swedish children.Acta Pediatr 1995; 34: 156–159.

    Google Scholar 

  7. Reusz GS, Dobos M, Byrd Det al. Urinary calcium and oxalate excretion in children 1995; 9: 39–44

    CAS  Google Scholar 

  8. Lorentz K. Improved determination of serum calcium with 2-cresolphthalein Complexone.Clin Chem Acta 1982; 126; 327–334.

    Article  CAS  Google Scholar 

  9. Kaufman JM, Martin LG, Seegmiller JE. Urine uric acid to creatinin ratio, a screening test for inherited disorders of purine metabolism.J Pediatr 1968; 4: 583–592.

    Google Scholar 

  10. Ginsbery JM, Chang BS, Matarese RAet al. Use of single voided urine samples to estimate proteinuria.N Eng J Med 1993; 309: 1543–1546.

    Article  Google Scholar 

  11. Chen YH, Lee AJ, Chen CHet al. Urinary mineral excretion among normal Taiwanese children.Pediatr Nephrol 1994; 8: 36–39.

    Article  PubMed  CAS  Google Scholar 

  12. Sweid HA, Bagga A, Vasvani Met al. Urinary excretion of minerals, oxalate and uric acid in north Indian children.Pediatr Nephrol 1997; 11: 189–192.

    Article  PubMed  CAS  Google Scholar 

  13. Juuti M, Heinonen P, Alhava EN. Seasonal variation in urinary excretion of calcium, oxalate, magnesium, and phosphate on free and standard diet in men with urolithiasis.Scan J Urol Nephrol 1981; 15: 137–141.

    Article  CAS  Google Scholar 

  14. Safarinejad MR. Urinary mineral excretion in healthy Iranian children.Pediatr Nephrol 2003: 18: 140–144.

    Article  PubMed  Google Scholar 

  15. Caren O, Akin M, Akturk Z. Normal urinary/ creatinin ratios in Turkish children.Indian Pediatrics 2003; 40: 884–887.

    Google Scholar 

  16. So NP, Osorio AV, Simon SDet al. Normal urinary calcium/creatinin ratios in African-American and Caucasian children.Pediatr Nephrol 2001; 16: 133–139.

    Article  PubMed  CAS  Google Scholar 

  17. Rath B, Aggarwal MK, Mishra TK, Talukdar B, Murthy NS, Kabi BC. Urinary calcium creatinine ratio and hypercalciuria.Indian Pediatr 1994; Mar; 31(3): 311–316.

    PubMed  CAS  Google Scholar 

  18. Vachvanichsanong P, Lebel L, Moore ES. Urinary calcium excretion in healthy Thai children.Pediatr Nephrol 2000; Aug; 14(8-9): 847–850.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Author notes

  1. Mahmmod Haji Aahmadi

    Present address: Department of Social Medicines and Health Babol Medical University, Iran

Authors and Affiliations

  1. Department of Pediatric Nephrology, Amirkola Children Hospital, Babol Medical University, 47317-41151, Iran

    Hadi Sorkhi

  2. Department of Social Medicines and Health Babol Medical University, Iran

    Hadi Sorkhi

Authors
  1. Hadi Sorkhi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Mahmmod Haji Aahmadi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Hadi Sorkhi.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sorkhi, H., Aahmadi, M.H. Urinary calcium to creatinin ratio in children. Indian J Pediatr 72, 1055–1056 (2005). https://doi.org/10.1007/BF02724412

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02724412

Key words

Search

Navigation