Abstract
A case of neonatal Bartter syndrome is reported. The baby born pre-term following a pregnancy complicated by polyhydramnios, presented at 7 months of age with failure to thrive, gastroenteritis and facial dysmorphisms. An unusual feature was the absence of the classical biochemical abnormality of hypochloremic alkalosis early in the course of the disease. Metabolic acidosis was the initial manifestation at 5 weeks of age. Awareness of this presentation is important to avoid delay in diagnosis and treatment.
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References
Shah MH, Batwar OD, Parulekar SV. Recurrent hydramnios as a result of Fetal Bartter’s Syndrome. (A case report).J Postgrad Med 1991; 37: 119–120.
Juan Rodriguez-Soriano. Bartter and related syndromes: The puzzle is almost solved.Pediatr Nephrol 1998; 12 : 315–327.
Seybeth HW, Roscher W, Schweer H, Kuhl PG, Mehls O, Scharer K. Congenital hypokalemia with hypercalciuria in preterm infants; a hyperprostaglandnuric tubular syndrome different from Bartter Syndrome.J Pediatr 1985; 107: 694–701.
Seyberth HW, Koniger SJ, Rascher W, Kuhl PG, Schweer H. Role of Prostaglandins in Hyperprostaglandin E Syndrome and in selected renal tubular disorders.Pediatr Nephrol 1987; 1: 491–497.
Proesmans W. Bartter Syndrome and its Neonatal Variant.Eur J Pediatr 1997; 156: 669–679.
Reinalter S, Devlieger H, Proesmans W. Neonatal Bartter Syndrome: Spontaneous resolution of all signs and symptoms.Pediatr Nephrol 1998; 12: 186–188.
Vargas-Poussou R, Feldmann D, Vollmer M, Konrad M, Kelly L, Vanden Heuvel LPet al. Novel Molecular variants of the NA-K-2C1 cotransporter gene are responsible for antenatal Bartter syndrome.Am J Hum Genet 1998; 62: 1332–1340.
Madrigal G, Sabario P, Mora F, Rincon G, Guay-Woodford LM. Bartter Syndrome in Costa Rica: a description of 20 cases.Pediatr Nephrol 1997; 11 : 296–301.
Mackie FE, Hodson EM, Roy LP, Knigh JF, Neonatal Bartter Syndrome-Use of indomethacin in the newborn period and prevention of growth failure.Pediatr Nephrol 1996; 10: 756–758.
Ammenti A, Montali S. “Neonatal variant” of Bartter syndrome presenting with acidosis.Pediatr Nephrol 1996; 10: 79–80.
Landau D, Shalev H, Ohaly M, Carmi R. Infantile variant of, Bartter Syndrome and sensorineural deafness: a new autosomal recessive disorder.Am J Med Genet 1995; 59: 454–459.
Proesmans W, Massa G, Vander Schueren-Lodeweyckx M. Growth from Birth to Adulthood with the Neonatal form of Bartter Syndrome.Pediatr Nephrol 1988; 2: 205–209.
Di Pietro, Proverbio MR, Tammaro V, Riccio E, Santoro C, Sarnelli Cet al. Fetal polyuria and decrease of electrolytes in amniotic fluid as principal markers of Bartter syndrome.Pediatr Med Chir 1997; 19: 267–268.
Matsushita Y, Suzuki Y, Oya N, Kajiura S, Okajma K, Venturaet al. Biochemical examination of mother’s urine is useful for prenatal diagnosis of Bartter’s Syndrome.Prenat Diagn 1999; 19(7): 671–673.
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Muranjan, M.N., Kantharia, V.C., Bavdekar, S.B. et al. Neonatal Bartter syndrome. Indian J Pediatr 69, 105–107 (2002). https://doi.org/10.1007/BF02723788
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DOI: https://doi.org/10.1007/BF02723788