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Patent ductus arteriosus in preterm neonates

The Indian Journal of Pediatrics volume 68, pages 981–984 (2001)Cite this article

Abstract

Failure of the ductus arteriosus to close within 48–96 hours of postnatal age results in a left to right shunt across the ductus and overloading of the pulmonary circulation. This is more likely to happen in premature neonates with respiratory distress syndrome. Deterioration in the respiratory status on day 3–4 in a ventilated neonate and unexplained metabolic acidosis may be the earliest indicators of a patent ductus arteriosus (PDA). Indomethacin is the main stay of medical management of PDA in preterm neonates. Guidelines for administration of indomethacin have been described in the protocol. Restricted fluid therapy may be beneficial in the prevention of PDA in preterm neonates. Presence of PDA in a term neonate should be investigated to rule out an underlying congenital heart disease.

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Affiliations

  1. Additional Professor, Division of Neonatology, Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, 110029, New Delhi, India

    Rajiv Aggarwal, Anurag Bajpai &  Ashok K. Deorari

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  1. Rajiv Aggarwal
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  2. Anurag Bajpai
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  3. Ashok K. Deorari
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  4. Vinod K. Paul
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Correspondence to Ashok K. Deorari.

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Aggarwal, R., Bajpai, A., Deorari, A.K. et al. Patent ductus arteriosus in preterm neonates. Indian J Pediatr 68, 981–984 (2001). https://doi.org/10.1007/BF02722601

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  • DOI: https://doi.org/10.1007/BF02722601

Key words

  • Ductus arteriosus
  • Pulmonary circutation
  • Preterm Neonates